BNTX vs REGN vs GILD Stock Comparison

BioNTech SE, Regeneron Pharmaceuticals and Gilead Sciences Prices as of Oct 27, 2026 Peers: Industry group
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BNTX BioNTech SE
$87.06 -11.6% 1M -17.9% 1Y
Market cap
$21.29B
P/E
–
Revenue (TTM)
$3.09B
Div. yield
–
Biotechnology Healthcare
GILD Gilead Sciences, Inc.
$159.08 +5.4% 1M +32.0% 1Y
Market cap
$198.21B
P/E
–
Revenue (TTM)
$30.46B
Div. yield
–
Biotechnology Healthcare
3 wins

Head to Head

9 decided of 12

Regeneron Pharmaceuticals leads on 6 of the 12 questions below (Regeneron Pharmaceuticals 6, Gilead Sciences 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBNTXREGNGILDLeader
Larger companyMarket capitalisation $21.29B $83.63B $198.21B GILD
Cheaper on earningsLower P/E, profitable companies only -10.8x 19.3x -61.2x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 14.3x — –
Faster revenue growthRevenue growth, trailing twelve months -1.1% +9.3% +5.5% REGN
More profitableNet margin, trailing twelve months -63.5% 27.9% -10.6% REGN
Better return on capitalReturn on invested capital -10.7% 9.6% -6.0% REGN
Less leveragedLower net debt / EBITDA 8.7x -1.4x 87.7x REGN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -17.9% +39.4% +32.0% REGN
Better 5-year returnAnnualised price return, 5 years -21.1%/yr +5.5%/yr +18.8%/yr GILD
Less volatileAnnualised volatility, 1 year 46.6% 32.8% 26.9% GILD
Higher overall scoreMean of the five percentile scores vs peers 64/100 72/100 61/100 REGN

Percentile Scorecard

BNTXREGNGILD

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBNTXREGNGILD
Valuation 91 #58 of 625 89 #71 of 625 90 #61 of 625
Growth 14 #520 of 602 42 #351 of 602 31 #416 of 602
Profitability 77 #129 of 551 90 #54 of 551 85 #83 of 551
Financial Health 89 #71 of 656 74 #172 of 656 21 #516 of 656
Shareholder Returns 51 #179 of 365 65 #129 of 365 77 #86 of 365
Overall 64 72 61
  • BNTX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • REGN ranked among 672 companies in Pharmaceuticals and Biotechnology
  • GILD ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBNTXREGNGILDSPY
1 month -11.6%+3.6%+5.4% -0.2%
3 months -5.8%+17.4%+18.4% +3.9%
6 months -14.7%+11.5%+23.1% +8.2%
Year to date -8.6%+5.7%+29.6% +12.9%
1 year -17.9%+39.4%+32.0% +12.3%
3 years -4.5%+5.3%+107.6% +87.4%
3 years, per year -1.5%+1.7%+27.6% +23.3%
5 years -69.3%+30.5%+136.2% +67.9%
5 years, per year -21.1%+5.5%+18.8% +10.9%
10 years —+123.4%+109.8% +261.1%
10 years, per year —+8.4%+7.7% +13.7%

Risk

MeasureBNTXREGNGILDSPY
Volatility, 1Y 46.6%32.8%26.9% 12.7%
Downside volatility, 1Y 46.5%30.0%24.0% 12.7%
Beta vs S&P 500, 1Y 0.950.470.30 1.00
Return / volatility, 1Y -0.381.201.19 0.97
Max drawdown, 5Y -78.4%-59.8%-29.4% -25.4%
From 52-week high -27.0%-4.2%0.0% -1.2%
52-week high $119.34$852.03$159.08 $779.14
52-week low $83.89$585.31$117.88 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBNTXREGNGILD
P/E now vs peer median -10.7xmedian 17.2x 19.4xmedian 17.2x -61.0xmedian 17.2x
P/S now vs peer median 7.1xmedian 9.0x 5.4xmedian 9.0x 6.5xmedian 9.0x
EV/EBITDA now vs peer median -5.7xmedian 16.3x 17.8xmedian 16.3x 838.3xmedian 16.3x
P/FCF now vs peer median 21.2xmedian 18.7x 22.3xmedian 18.7x 15.3xmedian 18.7x
P/B now vs peer median 1.1xmedian 2.2x 2.6xmedian 2.2x 16.7xmedian 2.2x
PEG now vs peer median 0.31median 0.33 7.29median 0.33 1.63median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBNTXREGNGILD
Revenue $3.09B $15.53B $30.46B
Gross profit $2.34B $13.18B $24.24B
Operating income -$2.33B $3.84B -$2.50B
Net income -$1.97B $4.33B -$3.24B
Free cash flow $1.04B $3.76B $12.94B
R&D $2.54B $6.28B $6.07B
EPS (diluted) $-8.13 $40.84 $-2.61
Cash & equivalents $11.13B $2.46B $3.18B
Total debt $102.80M $1.99B $26.25B
Shares (diluted) 241.70M 106.00M 1.24B
Enterprise value -$25.19B $49.83B $172.41B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBNTXREGNGILD
P/E -10.7x 19.4x -61.0x
P/FCF 21.2x 22.3x 15.3x
P/Operating cash flow 27.8x 17.9x 14.6x
P/S 7.1x 5.4x 6.5x
P/B 1.1x 2.6x 16.7x
P/Tangible book 1.1x 2.8x -89.6x
EV/EBITDA -5.7x 17.8x 838.3x
EV/EBIT -3.7x 20.3x -88.3x
EV/Revenue 2.8x 5.0x 7.2x
EV/FCF 8.4x 20.7x 17.0x
EV/Operating cash flow 11.0x 16.6x 16.3x
PEG (3Y EPS CAGR) 0.31 7.29 1.63

Growth

14 metrics
MetricBNTXREGNGILD
Revenue growth (1Y) -1.1% 9.3% 5.5%
Revenue CAGR (3Y) -31.0% 7.0% 3.6%
Gross profit growth (1Y) -6.4% 8.4% 6.9%
Gross profit CAGR (3Y) -34.2% 6.4% 3.7%
Operating income growth (1Y) -142.6% 0.1% -131.0%
Operating income CAGR (3Y) -33.8% -3.9% -31.9%
Net income growth (1Y) -417.0% -2.9% -151.3%
Net income CAGR (3Y) -34.6% 0.2% -37.3%
EPS growth (1Y) -393.7% -0.5% -151.8%
EPS CAGR (3Y) -34.9% 2.7% -37.5%
Operating cash flow growth (1Y) 142.8% -1.3% 37.3%
Operating cash flow CAGR (3Y) -56.6% -0.4% 12.5%
Free cash flow growth (1Y) 164.1% -2.4% 38.1%
Free cash flow CAGR (3Y) -53.1% -3.3% 13.2%

Profitability

14 metrics
MetricBNTXREGNGILD
Gross margin 75.5% 84.9% 79.6%
EBITDA margin -49.7% 28.1% 0.9%
Operating margin -75.2% 24.7% -8.2%
Pretax margin -61.4% 33.3% -6.4%
Net margin -63.5% 27.9% -10.6%
FCF margin 33.6% 24.2% 42.5%
Operating cash flow margin 25.6% 30.1% 44.5%
Return on equity -10.3% 13.7% -18.4%
Return on assets -9.0% 10.5% -6.1%
Return on invested capital -10.7% 9.6% -6.0%
Return on capital employed -9.9% 10.7% -6.0%
Asset turnover 0.1x 0.4x 0.6x
Cash conversion (OCF / net income) -0.4x 1.1x -4.2x
Stock comp / revenue 3.6% 6.4% 3.0%

Financial Health

11 metrics
MetricBNTXREGNGILD
Debt / assets 0.4% 4.8% 53.2%
Debt / equity 0.0x 0.1x 2.2x
Net debt / EBITDA 8.7x -1.4x 87.7x
Debt / FCF 0.1x 0.5x 2.0x
Liabilities / assets 12.7% 24.0% 76.0%
Equity / assets 87.3% 76.0% 24.0%
Interest coverage -41.1x 69.4x -2.5x
Current ratio 65.1x 3.3x 1.3x
Quick ratio 50.7x 2.6x 0.7x
Cash ratio 50.0x 1.4x 0.3x
Altman Z-score 6.31 7.33 3.74

Shareholder Returns

7 metrics
MetricBNTXREGNGILD
Dividend yield – 0.5% 2.0%
Net buyback yield -2.9% 3.0% 0.6%
Shareholder yield -2.9% 3.5% 2.6%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBNTXREGNGILD
Forward P/E – 14.3xFY2026 –
EPS, next fiscal year $-6.21FY2026 $57.08FY2026 $-0.39FY2026
EPS growth, next FY – +28.8%FY2026 -104.8%FY2026
EPS growth, the year after – +15.5% –
Revenue, next fiscal year $1.90BFY2026 $17.05BFY2026 $28.65BFY2026
Revenue growth, next FY -43.7%FY2026 +18.9%FY2026 -2.7%FY2026
Revenue growth, the year after +11.9% +13.0% +18.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBNTXREGNGILD
Held by institutions 19.4% 66.2% 89.6%
Institutions holding 281 1,325 2,290
Change in shares held, QoQ -1.2% +3.8% +5.1%
Institutions buying 136 604 1,113
Institutions selling 73 534 850
Buyers to sellers 1.86 1.13 1.31

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BNTXREGNGILD
BNTX 1.00 0.26 0.26
REGN 0.26 1.00 0.43
GILD 0.26 0.43 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, BNTX, REGN and GILD?

Gilead Sciences (GILD) is the largest by market capitalisation: BioNTech SE (BNTX) $21.29B, Regeneron Pharmaceuticals (REGN) $83.63B, Gilead Sciences (GILD) $198.21B.

Which company is growing faster?

Regeneron Pharmaceuticals (REGN) grew revenue fastest over the trailing twelve months: BioNTech SE (BNTX) -1.1%, Regeneron Pharmaceuticals (REGN) +9.3%, Gilead Sciences (GILD) +5.5%.

Which company is more profitable?

Regeneron Pharmaceuticals (REGN) has the highest net margin (BioNTech SE (BNTX) -63.5%, Regeneron Pharmaceuticals (REGN) 27.9%, Gilead Sciences (GILD) -10.6%). On return on invested capital, Regeneron Pharmaceuticals (REGN) leads (BioNTech SE (BNTX) -10.7%, Regeneron Pharmaceuticals (REGN) 9.6%, Gilead Sciences (GILD) -6.0%).

Which stock has performed better?

Over the past year Regeneron Pharmaceuticals (REGN) returned the most: BioNTech SE (BNTX) -17.9%, Regeneron Pharmaceuticals (REGN) +39.4%, Gilead Sciences (GILD) +32.0%. Over five years, Gilead Sciences (GILD) compounded fastest (BioNTech SE (BNTX) -21.1%/yr, Regeneron Pharmaceuticals (REGN) +5.5%/yr, Gilead Sciences (GILD) +18.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Gilead Sciences (GILD) has been the steadiest (BioNTech SE (BNTX) 46.6%, Regeneron Pharmaceuticals (REGN) 32.8%, Gilead Sciences (GILD) 26.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BNTX, REGN and GILD?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Regeneron Pharmaceuticals (REGN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.