BNTX vs MRNA vs ALNY Stock Comparison

BioNTech SE, Moderna and Alnylam Pharmaceuticals Prices as of Nov 5, 2026 Peers: Industry group
1 more company in this comparison (ARGX) Create a free account to keep reading and compare up to 10 companies.
BNTX BioNTech SE
$85.86 -10.3% 1M -17.0% 1Y
Market cap
$21.71B
P/E
–
Revenue (TTM)
$2.80B
Div. yield
–
Biotechnology Healthcare
2 wins
MRNA Moderna, Inc.
$241.46 +28.8% 1M +924.9% 1Y
Market cap
$96.34B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
3 wins

Head to Head

9 decided of 12

Alnylam Pharmaceuticals leads on 4 of the 12 questions below (Alnylam Pharmaceuticals 4, Moderna 3, BioNTech SE 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBNTXMRNAALNYLeader
Larger companyMarket capitalisation $21.71B $96.34B $20.97B MRNA
Cheaper on earningsLower P/E, profitable companies only -12.1x -30.5x 7.9x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 8.2x –
Faster revenue growthRevenue growth, trailing twelve months -20.8% -27.6% +60.8% ALNY
More profitableNet margin, trailing twelve months -61.4% -141.4% 52.8% ALNY
Better return on capitalReturn on invested capital -10.2% -43.3% — BNTX
Less leveragedLower net debt / EBITDA 12.2x 1.5x -3.1x ALNY
Higher dividend yieldTrailing dividend yield 0.00% — — –
Better 1-year returnPrice return, last 12 months -17.0% +924.9% -63.9% MRNA
Better 5-year returnAnnualised price return, 5 years -16.9%/yr +0.4%/yr -3.5%/yr MRNA
Less volatileAnnualised volatility, 1 year 47.1% 130.3% 58.5% BNTX
Higher overall scoreMean of the five percentile scores vs peers 61/100 57/100 82/100 ALNY

Percentile Scorecard

BNTXMRNAALNY

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBNTXMRNAALNY
Valuation 87 #85 of 634 69 #199 of 634 92 #54 of 634
Growth 10 #545 of 608 19 #495 of 608 99 #8 of 608
Profitability 73 #153 of 557 57 #241 of 557 90 #56 of 557
Financial Health 88 #79 of 654 53 #307 of 654 62 #250 of 654
Shareholder Returns 49 #208 of 403 86 #59 of 403 67 #135 of 403
Overall 61 57 82
  • BNTX ranked among 671 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 671 companies in Pharmaceuticals and Biotechnology
  • ALNY ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBNTXMRNAALNYSPY
1 month -10.3%+28.8%-30.0% -5.9%
3 months -5.8%+348.3%-27.5% -4.6%
6 months -7.7%+397.4%-47.1% +0.2%
Year to date -9.8%+718.8%-60.6% +7.5%
1 year -17.0%+924.9%-63.9% +8.2%
3 years -13.9%+235.0%-6.3% +68.3%
3 years, per year -4.9%+49.7%-2.1% +19.0%
5 years -60.4%+1.9%-16.3% +56.5%
5 years, per year -16.9%+0.4%-3.5% +9.4%
10 years ——+364.2% +251.5%
10 years, per year ——+16.6% +13.4%

Risk

MeasureBNTXMRNAALNYSPY
Volatility, 1Y 47.1%130.3%58.5% 13.6%
Downside volatility, 1Y 47.0%79.2%74.5% 14.2%
Beta vs S&P 500, 1Y 1.032.240.44 1.00
Return / volatility, 1Y -0.367.10-1.09 0.60
Max drawdown, 5Y -78.4%-93.9%-68.1% -25.4%
From 52-week high -28.1%-6.5%-66.9% -5.9%
52-week high $119.34$258.38$473.29 $779.14
52-week low $83.89$22.36$156.66 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBNTXMRNAALNY
P/E now vs peer median -12.1xmedian 17.8x -30.5xmedian 17.8x 7.9xmedian 17.8x
P/S now vs peer median 7.8xmedian 8.1x 43.2xmedian 8.1x 4.2xmedian 8.1x
EV/EBITDA now vs peer median -7.5xmedian 15.7x -29.8xmedian 15.7x 17.2xmedian 15.7x
P/FCF now vs peer median -788.2xmedian 21.0x -77.4xmedian 21.0x 26.0xmedian 21.0x
P/B now vs peer median 1.1xmedian 2.0x 14.2xmedian 2.0x 5.8xmedian 2.0x
PEG now vs peer median 0.32median 0.36 0.47median 0.36 0.09median 0.36

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBNTXMRNAALNY
Revenue $2.80B $2.23B $5.01B
Gross profit $2.10B $521.00M $3.88B
Operating income -$2.13B -$3.32B $977.59M
Net income -$1.72B -$3.15B $2.65B
Free cash flow -$27.55M -$1.24B $806.31M
R&D $2.74B $2.88B $1.56B
EPS (diluted) $-7.11 $-7.92 $19.16
Cash & equivalents $11.57B $1.72B $1.75B
Total debt $123.50M $591.00M $361.53M
Shares (diluted) 241.70M 398.00M 138.28M
Enterprise value -$37.80B $75.70B $8.16B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBNTXMRNAALNY
P/E -12.1x -30.5x 7.9x
P/FCF -788.2x -77.4x 26.0x
P/Operating cash flow -80.5x -89.8x 21.9x
P/S 7.8x 43.2x 4.2x
P/B 1.1x 14.2x 5.8x
P/Tangible book 1.1x 14.2x 5.8x
EV/EBITDA -7.5x -29.8x 17.2x
EV/EBIT -3.9x -27.6x 18.2x
EV/Revenue 3.0x 41.2x 3.5x
EV/FCF -301.6x -73.8x 22.0x
EV/Operating cash flow -30.8x -85.6x 18.6x
PEG (3Y EPS CAGR) 0.32 0.47 0.09

Growth

14 metrics
MetricBNTXMRNAALNY
Revenue growth (1Y) -20.8% -27.6% 60.8%
Revenue CAGR (3Y) -25.9% -40.6% 42.7%
Gross profit growth (1Y) -28.3% -67.8% 49.6%
Gross profit CAGR (3Y) -30.5% -56.0% 37.8%
Operating income growth (1Y) -107.5% -1.4% 269.3%
Operating income CAGR (3Y) -37.6% -103.9% 68.2%
Net income growth (1Y) -172.4% -8.5% 2,137%
Net income CAGR (3Y) -37.6% -66.4% 93.1%
EPS growth (1Y) -164.3% -5.8% 2,122%
EPS CAGR (3Y) -38.0% -65.1% 90.7%
Operating cash flow growth (1Y) -13.4% 60.2% 351.6%
Operating cash flow CAGR (3Y) -27.0% -68.1% 685.4%
Free cash flow growth (1Y) 35.2% 64.4% 382.3%
Free cash flow CAGR (3Y) -26.1% -18.2% 141.7%

Profitability

14 metrics
MetricBNTXMRNAALNY
Gross margin 74.9% 23.4% 77.4%
EBITDA margin -39.3% -138.2% 20.6%
Operating margin -76.0% -149.0% 19.5%
Pretax margin -59.7% -138.6% 15.6%
Net margin -61.4% -141.4% 52.8%
FCF margin -1.0% -55.8% 16.1%
Operating cash flow margin -9.6% -48.2% 19.1%
Return on equity -9.4% -44.5% 106.9%
Return on assets -8.2% -28.1% 39.1%
Return on invested capital -10.2% -43.3% –
Return on capital employed -9.3% -38.2% 20.7%
Asset turnover 0.1x 0.2x 0.7x
Cash conversion (OCF / net income) 0.2x 0.3x 0.4x
Stock comp / revenue 3.6% 20.7% 6.1%

Financial Health

11 metrics
MetricBNTXMRNAALNY
Debt / assets 0.5% 5.4% 4.5%
Debt / equity 0.0x 0.1x 0.1x
Net debt / EBITDA 12.2x 1.5x -3.1x
Debt / FCF -4.5x -0.5x 0.4x
Liabilities / assets 12.2% 38.3% 54.9%
Equity / assets 87.8% 61.7% 45.1%
Interest coverage -57.9x – 3.2x
Current ratio 64.2x 2.3x 2.5x
Quick ratio 51.6x 2.0x 2.3x
Cash ratio 48.8x 2.0x 1.7x
Altman Z-score 6.56 13.98 3.62

Shareholder Returns

7 metrics
MetricBNTXMRNAALNY
Dividend yield – – –
Net buyback yield -3.7% -0.1% -0.5%
Shareholder yield -3.7% -0.1% -0.5%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBNTXMRNAALNY
Forward P/E – – 8.2xFY2026
EPS, next fiscal year $-6.13FY2026 $-8.02FY2026 $19.15FY2026
EPS growth, next FY – – +721.9%FY2026
EPS growth, the year after – – -56.0%
Revenue, next fiscal year $1.94BFY2026 $2.04BFY2026 $5.65BFY2026
Revenue growth, next FY -42.4%FY2026 +5.1%FY2026 +52.2%FY2026
Revenue growth, the year after +13.5% +26.8% +23.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBNTXMRNAALNY
Held by institutions 19.4% 80.2% 99.7%
Institutions holding 283 786 788
Change in shares held, QoQ -1.2% +3.4% +3.8%
Institutions buying 136 403 412
Institutions selling 73 239 279
Buyers to sellers 1.86 1.69 1.48

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BNTXMRNAALNY
BNTX 1.00 0.60 0.21
MRNA 0.60 1.00 0.18
ALNY 0.21 0.18 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, BNTX, MRNA and ALNY?

Moderna (MRNA) is the largest by market capitalisation: BioNTech SE (BNTX) $21.71B, Moderna (MRNA) $96.34B, Alnylam Pharmaceuticals (ALNY) $20.97B.

Which company is growing faster?

Alnylam Pharmaceuticals (ALNY) grew revenue fastest over the trailing twelve months: BioNTech SE (BNTX) -20.8%, Moderna (MRNA) -27.6%, Alnylam Pharmaceuticals (ALNY) +60.8%.

Which company is more profitable?

Alnylam Pharmaceuticals (ALNY) has the highest net margin (BioNTech SE (BNTX) -61.4%, Moderna (MRNA) -141.4%, Alnylam Pharmaceuticals (ALNY) 52.8%). On return on invested capital, BioNTech SE (BNTX) leads (BioNTech SE (BNTX) -10.2%, Moderna (MRNA) -43.3%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: BioNTech SE (BNTX) -17.0%, Moderna (MRNA) +924.9%, Alnylam Pharmaceuticals (ALNY) -63.9%. Over five years, Moderna (MRNA) compounded fastest (BioNTech SE (BNTX) -16.9%/yr, Moderna (MRNA) +0.4%/yr, Alnylam Pharmaceuticals (ALNY) -3.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, BioNTech SE (BNTX) has been the steadiest (BioNTech SE (BNTX) 47.1%, Moderna (MRNA) 130.3%, Alnylam Pharmaceuticals (ALNY) 58.5%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BNTX, MRNA and ALNY?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Alnylam Pharmaceuticals (ALNY) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.