BEAM vs SLDB vs CRSP Stock Comparison

Beam Therapeutics, Solid Biosciences and CRISPR Therapeutics AG Prices as of Oct 29, 2026 Peers: Industry group
1 more company in this comparison (VCEL) Create a free account to keep reading and compare up to 10 companies.
BEAM Beam Therapeutics Inc.
$28.84 +17.6% 1M +16.4% 1Y
Market cap
$2.80B
P/E
–
Revenue (TTM)
$156.04M
Div. yield
–
Gene and Cell Therapy Healthcare
5 wins
SLDB Solid Biosciences Inc.
$6.39 -10.8% 1M +16.4% 1Y
Market cap
$870.75M
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
CRSP CRISPR Therapeutics AG
$54.26 -3.1% 1M -13.3% 1Y
Market cap
$4.94B
P/E
–
Revenue (TTM)
$13.39M
Div. yield
–
Gene and Cell Therapy Healthcare
3 wins

Head to Head

8 decided of 12

Beam Therapeutics leads on 5 of the 12 questions below (Beam Therapeutics 5, CRISPR Therapeutics AG 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBEAMSLDBCRSPLeader
Larger companyMarket capitalisation $2.80B $870.75M $4.94B CRSP
Cheaper on earningsLower P/E, profitable companies only -32.7x -4.2x -10.9x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months +158.9% — -64.8% BEAM
More profitableNet margin, trailing twelve months -54.7% — -3,368.7% BEAM
Better return on capitalReturn on invested capital — — -22.6% –
Less leveragedLower net debt / EBITDA 3.0x — 3.4x BEAM
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +16.4% +16.4% -13.3% BEAM
Better 5-year returnAnnualised price return, 5 years -20.1%/yr -26.8%/yr -9.9%/yr CRSP
Less volatileAnnualised volatility, 1 year 70.4% 78.2% 57.3% CRSP
Higher overall scoreMean of the five percentile scores vs peers 70/100 42/100 45/100 BEAM

Percentile Scorecard

BEAMSLDBCRSP

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBEAMSLDBCRSP
Valuation 57 #269 of 624 35 #408 of 624 51 #308 of 624
Growth 77 #138 of 601 20 #484 of 601 32 #412 of 601
Profitability 64 #193 of 541 50 #273 of 541 32 #367 of 541
Financial Health 81 #122 of 647 88 #77 of 647 71 #188 of 647
Shareholder Returns 68 #116 of 359 19 #292 of 359 38 #222 of 359
Overall 70 42 45
  • BEAM ranked among 671 companies in Pharmaceuticals and Biotechnology
  • SLDB ranked among 671 companies in Pharmaceuticals and Biotechnology
  • CRSP ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBEAMSLDBCRSPSPY
1 month +17.6%-10.8%-3.1% +0.7%
3 months +8.9%-24.7%+12.0% +3.7%
6 months -4.9%-12.0%+3.7% +7.1%
Year to date +4.0%+13.3%+3.5% +12.8%
1 year +16.4%+16.4%-13.3% +11.9%
3 years +50.9%+208.7%+39.4% +85.2%
3 years, per year +14.7%+45.6%+11.7% +22.8%
5 years -67.5%-79.0%-40.6% +67.6%
5 years, per year -20.1%-26.8%-9.9% +10.9%
10 years ——+224.1% +262.0%
10 years, per year ——+12.5% +13.7%

Risk

MeasureBEAMSLDBCRSPSPY
Volatility, 1Y 70.4%78.2%57.3% 12.7%
Downside volatility, 1Y 63.6%76.3%53.8% 12.6%
Beta vs S&P 500, 1Y 2.092.131.84 1.00
Return / volatility, 1Y 0.230.21-0.23 0.94
Max drawdown, 5Y -85.3%-94.9%-67.7% -25.4%
From 52-week high -23.9%-42.7%-15.2% -1.2%
52-week high $37.92$11.15$63.99 $779.14
52-week low $20.60$3.93$44.34 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBEAMSLDBCRSP
P/E now vs peer median -35.2xmedian 17.8x -4.4xmedian 17.8x -11.6xmedian 17.8x
P/S now vs peer median 19.1xmedian 9.1x —median 9.1x 391.6xmedian 9.1x
EV/EBITDA now vs peer median -5.4xmedian 15.0x -2.6xmedian 15.0x -6.7xmedian 15.0x
P/FCF now vs peer median -8.0xmedian 21.7x -4.9xmedian 21.7x -14.1xmedian 21.7x
P/B now vs peer median 2.8xmedian 2.2x 2.5xmedian 2.2x 3.0xmedian 2.2x
PEG now vs peer median -0.83median 0.35 -0.14median 0.35 -3.01median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBEAMSLDBCRSP
Revenue $156.04M – $13.39M
Operating income -$378.02M -$212.15M -$534.34M
Net income -$86.52M -$207.10M -$451.14M
Free cash flow -$372.77M -$187.82M -$371.33M
R&D $408.66M $167.40M $278.15M
EPS (diluted) $-0.82 $-1.44 $-4.67
Cash & equivalents $219.83M $159.39M $291.34M
Total debt $100.26M – $586.20M
Shares (diluted) 104.33M 143.69M 96.51M
Enterprise value -$1.89B -$311.60M -$3.76B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBEAMSLDBCRSP
P/E -35.2x -4.4x -11.6x
P/FCF -8.0x -4.9x -14.1x
P/Operating cash flow -8.3x -4.9x -14.2x
P/S 19.1x – 391.6x
P/B 2.8x 2.5x 3.0x
P/Tangible book 2.8x 2.5x 3.0x
EV/EBITDA -5.4x -2.6x -6.7x
EV/EBIT -5.1x -2.5x -6.5x
EV/Revenue 12.3x – 258.9x
EV/FCF -5.2x -2.9x -9.3x
EV/Operating cash flow -5.4x -2.9x -9.4x
PEG (3Y EPS CAGR) -0.83 -0.14 -3.01

Growth

14 metrics
MetricBEAMSLDBCRSP
Revenue growth (1Y) 158.9% – -64.8%
Revenue CAGR (3Y) 24.9% – -57.1%
Gross profit growth (1Y) – – –
Gross profit CAGR (3Y) – – –
Operating income growth (1Y) 15.2% -35.3% 3.3%
Operating income CAGR (3Y) 0.3% -22.8% -4.1%
Net income growth (1Y) 78.2% -34.4% 3.6%
Net income CAGR (3Y) 35.8% -31.9% -2.7%
EPS growth (1Y) 79.0% 11.9% 13.0%
EPS CAGR (3Y) 42.4% 32.0% 3.9%
Operating cash flow growth (1Y) -4.2% -52.4% -13.8%
Operating cash flow CAGR (3Y) -2.0% -19.2% -2.5%
Free cash flow growth (1Y) -4.8% -52.3% -14.1%
Free cash flow CAGR (3Y) 0.7% -18.4% -0.9%

Profitability

14 metrics
MetricBEAMSLDBCRSP
Gross margin – – –
EBITDA margin -228.0% – -3,850%
Operating margin -242.3% – -3,990%
Pretax margin -54.4% – -3,346%
Net margin -54.7% – -3,369%
FCF margin -238.9% – -2,773%
Operating cash flow margin -230.3% – -2,760%
Return on equity -7.6% -55.4% -25.3%
Return on assets -5.9% -49.1% -16.8%
Return on invested capital – – -22.6%
Return on capital employed -27.9% -54.0% -20.9%
Asset turnover 0.1x – 0.0x
Cash conversion (OCF / net income) 4.2x 0.9x 0.8x
Stock comp / revenue 52.2% – 510.2%

Financial Health

11 metrics
MetricBEAMSLDBCRSP
Debt / assets 7.2% – 22.1%
Debt / equity 0.1x – 0.3x
Net debt / EBITDA 3.0x – 3.4x
Debt / FCF -0.3x – -1.6x
Liabilities / assets 23.0% 11.1% 34.1%
Equity / assets 77.0% 88.9% 65.9%
Interest coverage – – –
Current ratio 14.6x 13.8x 17.8x
Quick ratio 14.3x 13.2x 17.8x
Cash ratio 14.3x 13.2x 17.8x
Altman Z-score 3.85 – 2.69

Shareholder Returns

7 metrics
MetricBEAMSLDBCRSP
Dividend yield – – –
Net buyback yield -0.5% -26.2% -8.1%
Shareholder yield -0.5% -26.2% -8.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBEAMSLDBCRSP
EPS, next fiscal year $-4.22FY2026 $-1.63FY2026 $-4.10FY2026
Revenue, next fiscal year $49.46MFY2026 $0.00FY2026 $38.73MFY2026
Revenue growth, next FY -64.6%FY2026 – +1,003.4%FY2026
Revenue growth, the year after +23.6% – +266.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBEAMSLDBCRSP
Held by institutions 100.0% 79.7% 78.9%
Institutions holding 277 157 519
Change in shares held, QoQ +1.0% +18.9% -1.0%
Institutions buying 154 101 238
Institutions selling 75 37 139
Buyers to sellers 2.05 2.73 1.71

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BEAMSLDBCRSP
BEAM 1.00 0.53 0.76
SLDB 0.53 1.00 0.50
CRSP 0.76 0.50 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, BEAM, SLDB and CRSP?

CRISPR Therapeutics AG (CRSP) is the largest by market capitalisation: Beam Therapeutics (BEAM) $2.80B, Solid Biosciences (SLDB) $870.75M, CRISPR Therapeutics AG (CRSP) $4.94B.

Which company is growing faster?

Beam Therapeutics (BEAM) grew revenue fastest over the trailing twelve months: Beam Therapeutics (BEAM) +158.9%, CRISPR Therapeutics AG (CRSP) -64.8%.

Which company is more profitable?

Beam Therapeutics (BEAM) has the highest net margin (Beam Therapeutics (BEAM) -54.7%, CRISPR Therapeutics AG (CRSP) -3,368.7%).

Which stock has performed better?

Over the past year Beam Therapeutics (BEAM) returned the most: Beam Therapeutics (BEAM) +16.4%, Solid Biosciences (SLDB) +16.4%, CRISPR Therapeutics AG (CRSP) -13.3%. Over five years, CRISPR Therapeutics AG (CRSP) compounded fastest (Beam Therapeutics (BEAM) -20.1%/yr, Solid Biosciences (SLDB) -26.8%/yr, CRISPR Therapeutics AG (CRSP) -9.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, CRISPR Therapeutics AG (CRSP) has been the steadiest (Beam Therapeutics (BEAM) 70.4%, Solid Biosciences (SLDB) 78.2%, CRISPR Therapeutics AG (CRSP) 57.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BEAM, SLDB and CRSP?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Beam Therapeutics (BEAM) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.