BEAM vs LEGN vs SRPT Stock Comparison

Beam Therapeutics, Legend Biotech and Sarepta Therapeutics Prices as of Nov 4, 2026 Peers: Industry group
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BEAM Beam Therapeutics Inc.
$27.79 +8.3% 1M +22.2% 1Y
Market cap
$2.74B
P/E
–
Revenue (TTM)
$146.64M
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins
LEGN Legend Biotech Corp
$22.77 +21.3% 1M -29.0% 1Y
Market cap
$4.35B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
5 wins

Head to Head

9 decided of 12

Legend Biotech leads on 5 of the 12 questions below (Legend Biotech 5, Beam Therapeutics 2, Sarepta Therapeutics 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBEAMLEGNSRPTLeader
Larger companyMarket capitalisation $2.74B $4.35B $1.91B LEGN
Cheaper on earningsLower P/E, profitable companies only -25.3x -47.5x -16.4x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 6.6x –
Faster revenue growthRevenue growth, trailing twelve months +163.3% +59.5% -20.4% BEAM
More profitableNet margin, trailing twelve months -73.9% -7.2% -5.9% SRPT
Better return on capitalReturn on invested capital — -4.2% -6.1% LEGN
Less leveragedLower net debt / EBITDA 2.5x -130.2x -0.6x LEGN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +22.2% -29.0% +17.2% BEAM
Better 5-year returnAnnualised price return, 5 years -20.9%/yr -14.1%/yr -26.6%/yr LEGN
Less volatileAnnualised volatility, 1 year 70.4% 72.7% 69.7% SRPT
Higher overall scoreMean of the five percentile scores vs peers 67/100 74/100 67/100 LEGN

Percentile Scorecard

BEAMLEGNSRPT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBEAMLEGNSRPT
Valuation 54 #291 of 634 88 #77 of 634 96 #26 of 634
Growth 74 #161 of 607 97 #21 of 607 63 #223 of 607
Profitability 64 #204 of 557 80 #110 of 557 80 #113 of 557
Financial Health 79 #141 of 654 60 #263 of 654 34 #434 of 654
Shareholder Returns 66 #135 of 400 44 #223 of 400 61 #158 of 400
Overall 67 74 67
  • BEAM ranked among 671 companies in Pharmaceuticals and Biotechnology
  • LEGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • SRPT ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBEAMLEGNSRPTSPY
1 month +8.3%+21.3%+8.6% -1.0%
3 months +2.7%+19.5%+19.2% -0.4%
6 months -14.1%-21.4%-17.5% +4.5%
Year to date +0.3%+4.7%-11.8% +12.4%
1 year +22.2%-29.0%+17.2% +13.6%
3 years +13.5%-65.5%-75.7% +76.4%
3 years, per year +4.3%-29.9%-37.6% +20.8%
5 years -69.0%-53.3%-78.6% +63.7%
5 years, per year -20.9%-14.1%-26.6% +10.4%
10 years ——-51.6% +267.7%
10 years, per year ——-7.0% +13.9%

Risk

MeasureBEAMLEGNSRPTSPY
Volatility, 1Y 70.4%72.7%69.7% 12.8%
Downside volatility, 1Y 63.7%62.9%63.2% 12.7%
Beta vs S&P 500, 1Y 2.100.531.78 1.00
Return / volatility, 1Y 0.32-0.400.25 1.06
Max drawdown, 5Y -85.3%-78.2%-92.7% -25.4%
From 52-week high -26.7%-37.2%-20.3% -1.6%
52-week high $37.92$36.28$23.83 $779.14
52-week low $20.60$16.65$14.86 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBEAMLEGNSRPT
P/E now vs peer median -26.9xmedian 18.0x -45.8xmedian 18.0x -17.1xmedian 18.0x
P/S now vs peer median 19.6xmedian 9.1x 3.3xmedian 9.1x 1.0xmedian 9.1x
EV/EBITDA now vs peer median -5.2xmedian 16.2x 927.8xmedian 16.2x -21.0xmedian 16.2x
P/FCF now vs peer median -7.2xmedian 21.7x -65.0xmedian 21.7x 24.5xmedian 21.7x
P/B now vs peer median 3.0xmedian 2.2x 3.4xmedian 2.2x 1.3xmedian 2.2x
PEG now vs peer median -0.74median 0.38 -0.97median 0.38 -0.33median 0.38

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBEAMLEGNSRPT
Revenue $146.64M $1.27B $1.97B
Gross profit – $727.10M $1.17B
Operating income -$392.54M -$55.25M -$143.25M
Net income -$108.35M -$80.39M -$136.73M
Free cash flow -$398.24M -$64.60M $81.85M
R&D $409.01M $396.15M $789.44M
EPS (diluted) $-1.03 $-0.50 $-1.11
Cash & equivalents $213.27M $672.90M $571.15M
Total debt $100.36M $156.40M $847.62M
Shares (diluted) 104.70M 184.32M 105.43M
Enterprise value -$1.91B $1.85B -$1.32B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBEAMLEGNSRPT
P/E -26.9x -45.8x -17.1x
P/FCF -7.2x -65.0x 24.5x
P/Operating cash flow -7.4x -46.9x 18.1x
P/S 19.6x 3.3x 1.0x
P/B 3.0x 3.4x 1.3x
P/Tangible book 3.0x 3.4x 1.3x
EV/EBITDA -5.2x 927.8x -21.0x
EV/EBIT -4.9x -66.6x -14.4x
EV/Revenue 13.2x 2.9x 1.0x
EV/FCF -4.9x -57.0x 25.2x
EV/Operating cash flow -5.0x -41.2x 18.6x
PEG (3Y EPS CAGR) -0.74 -0.97 -0.33

Growth

14 metrics
MetricBEAMLEGNSRPT
Revenue growth (1Y) 163.3% 59.5% -20.4%
Revenue CAGR (3Y) 21.6% 97.6% 25.3%
Gross profit growth (1Y) – 42.4% -40.7%
Gross profit CAGR (3Y) – 147.5% 10.6%
Operating income growth (1Y) 15.8% 75.3% -15,270%
Operating income CAGR (3Y) 0.5% 49.1% 34.5%
Net income growth (1Y) 73.8% 75.3% -135.9%
Net income CAGR (3Y) 29.8% 46.7% 46.8%
EPS growth (1Y) 74.3% 72.0% -215.7%
EPS CAGR (3Y) 36.1% 47.0% 52.3%
Operating cash flow growth (1Y) -14.9% 67.5% 136.9%
Operating cash flow CAGR (3Y) -3.2% 37.1% 30.6%
Free cash flow growth (1Y) -13.0% 77.8% 118.1%
Free cash flow CAGR (3Y) -0.5% 44.5% 29.1%

Profitability

14 metrics
MetricBEAMLEGNSRPT
Gross margin – 57.2% 59.1%
EBITDA margin -252.4% 0.3% -5.0%
Operating margin -267.7% -4.3% -7.3%
Pretax margin -73.2% -4.4% -6.6%
Net margin -73.9% -7.2% -5.9%
FCF margin -271.6% -5.1% 4.1%
Operating cash flow margin -265.0% -7.0% 5.6%
Return on equity -10.6% -8.3% -9.0%
Return on assets -8.1% -5.5% -4.3%
Return on invested capital – -4.2% -6.1%
Return on capital employed -31.5% -4.3% -5.3%
Asset turnover 0.1x 0.8x 0.6x
Cash conversion (OCF / net income) 3.6x 1.1x -0.8x
Stock comp / revenue 52.7% 5.2% 6.3%

Financial Health

11 metrics
MetricBEAMLEGNSRPT
Debt / assets 7.9% 8.9% 26.6%
Debt / equity 0.1x 0.1x 0.6x
Net debt / EBITDA 2.5x -130.2x -0.6x
Debt / FCF -0.3x -2.4x 10.4x
Liabilities / assets 24.9% 29.8% 52.1%
Equity / assets 75.1% 70.2% 47.9%
Interest coverage – -4.8x –
Current ratio 13.0x 3.0x 4.4x
Quick ratio 12.7x 1.7x 2.4x
Cash ratio 12.7x 1.7x 1.6x
Altman Z-score 3.27 7.00 -0.15

Shareholder Returns

7 metrics
MetricBEAMLEGNSRPT
Dividend yield – – –
Net buyback yield -0.5% -5.1% -1.1%
Shareholder yield -0.5% -5.1% -1.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBEAMLEGNSRPT
Forward P/E – – 6.6xFY2026
EPS, next fiscal year $-4.22FY2026 $-0.04FY2026 $2.88FY2026
EPS growth, the year after – – -88.5%
Revenue, next fiscal year $49.46MFY2026 $1.37BFY2026 $1.76BFY2026
Revenue growth, next FY -64.6%FY2026 +32.9%FY2026 -20.1%FY2026
Revenue growth, the year after +23.6% +35.9% -21.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBEAMLEGNSRPT
Held by institutions 100.0% 55.9% 100.0%
Institutions holding 277 218 326
Change in shares held, QoQ +1.0% +7.3% +4.5%
Institutions buying 154 117 148
Institutions selling 75 78 117
Buyers to sellers 2.05 1.50 1.26

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BEAMLEGNSRPT
BEAM 1.00 0.10 0.37
LEGN 0.10 1.00 0.11
SRPT 0.37 0.11 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, BEAM, LEGN and SRPT?

Legend Biotech (LEGN) is the largest by market capitalisation: Beam Therapeutics (BEAM) $2.74B, Legend Biotech (LEGN) $4.35B, Sarepta Therapeutics (SRPT) $1.91B.

Which company is growing faster?

Beam Therapeutics (BEAM) grew revenue fastest over the trailing twelve months: Beam Therapeutics (BEAM) +163.3%, Legend Biotech (LEGN) +59.5%, Sarepta Therapeutics (SRPT) -20.4%.

Which company is more profitable?

Sarepta Therapeutics (SRPT) has the highest net margin (Beam Therapeutics (BEAM) -73.9%, Legend Biotech (LEGN) -7.2%, Sarepta Therapeutics (SRPT) -5.9%). On return on invested capital, Legend Biotech (LEGN) leads (Legend Biotech (LEGN) -4.2%, Sarepta Therapeutics (SRPT) -6.1%).

Which stock has performed better?

Over the past year Beam Therapeutics (BEAM) returned the most: Beam Therapeutics (BEAM) +22.2%, Legend Biotech (LEGN) -29.0%, Sarepta Therapeutics (SRPT) +17.2%. Over five years, Legend Biotech (LEGN) compounded fastest (Beam Therapeutics (BEAM) -20.9%/yr, Legend Biotech (LEGN) -14.1%/yr, Sarepta Therapeutics (SRPT) -26.6%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Sarepta Therapeutics (SRPT) has been the steadiest (Beam Therapeutics (BEAM) 70.4%, Legend Biotech (LEGN) 72.7%, Sarepta Therapeutics (SRPT) 69.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BEAM, LEGN and SRPT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Legend Biotech (LEGN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.