AZN vs RGC vs AUPH Stock Comparison

Astrazeneca, Regencell Bioscience Holdings and Aurinia Pharmaceuticals Prices as of Oct 29, 2026 Peers: Industry group
AZN Astrazeneca Plc
$174.51 +6.3% 1M +6.1% 1Y
Market cap
$270.49B
P/E
25.9x
Revenue (TTM)
$58.67B
Div. yield
1.37%
Pharmaceuticals Healthcare
3 wins

Head to Head

9 decided of 12

Aurinia Pharmaceuticals leads on 5 of the 12 questions below (Aurinia Pharmaceuticals 5, Astrazeneca 3, Regencell Bioscience Holdings 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAZNRGCAUPHLeader
Larger companyMarket capitalisation $270.49B $3.40B $2.29B AZN
Cheaper on earningsLower P/E, profitable companies only 25.9x -290.0x 7.1x AUPH
Cheaper on forward earningsLower price / next fiscal year consensus EPS 17.5x — 17.9x AZN
Faster revenue growthRevenue growth, trailing twelve months +9.4% — +19.8% AUPH
More profitableNet margin, trailing twelve months 17.8% — 100.8% AUPH
Better return on capitalReturn on invested capital 23.3% — — –
Less leveragedLower net debt / EBITDA 1.4x — — –
Higher dividend yieldTrailing dividend yield 1.37% 0.00% — –
Better 1-year returnPrice return, last 12 months +6.1% -58.7% +40.8% AUPH
Better 5-year returnAnnualised price return, 5 years +6.9%/yr +81.0%/yr -12.3%/yr RGC
Less volatileAnnualised volatility, 1 year 27.5% 142.7% 37.0% AZN
Higher overall scoreMean of the five percentile scores vs peers 71/100 — 90/100 AUPH

Percentile Scorecard

AZNRGCAUPH

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAZNRGCAUPH
Valuation 85 #96 of 624 38 #388 of 624 93 #44 of 624
Growth 70 #183 of 601 – 96 #25 of 601
Profitability 94 #33 of 541 – 97 #16 of 541
Financial Health 36 #415 of 647 90 #67 of 647 74 #172 of 647
Shareholder Returns 70 #110 of 359 – 92 #31 of 359
Overall 71 – 90
  • AZN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • RGC ranked among 671 companies in Pharmaceuticals and Biotechnology
  • AUPH ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAZNRGCAUPHSPY
1 month +6.3%+10.6%+4.8% +0.7%
3 months +1.8%+15.5%+14.7% +3.7%
6 months -6.9%-76.5%+11.8% +7.1%
Year to date -5.1%-67.3%+7.9% +12.8%
1 year +6.1%-58.7%+40.8% +11.9%
3 years +38.6%+1,564.6%+134.1% +85.2%
3 years, per year +11.5%+155.5%+32.8% +22.8%
5 years +39.9%+1,841.1%-48.0% +67.6%
5 years, per year +6.9%+81.0%-12.3% +10.9%
10 years +205.1%—+432.8% +262.0%
10 years, per year +11.8%—+18.2% +13.7%

Risk

MeasureAZNRGCAUPHSPY
Volatility, 1Y 27.5%142.7%37.0% 12.7%
Downside volatility, 1Y 27.2%134.5%33.7% 12.6%
Beta vs S&P 500, 1Y 0.211.500.54 1.00
Return / volatility, 1Y 0.22-0.411.10 0.94
Max drawdown, 5Y -27.9%-93.9%-87.4% -25.4%
From 52-week high -16.7%-87.0%-7.6% -1.2%
52-week high $209.48$52.88$18.62 $779.14
52-week low $155.60$4.78$12.12 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAZNRGCAUPH
P/E now vs peer median 25.9xmedian 17.8x -290.0xmedian 17.8x 7.1xmedian 17.8x
P/S now vs peer median 4.6xmedian 9.1x —median 9.1x 7.3xmedian 9.1x
EV/EBITDA now vs peer median 14.7xmedian 15.0x —median 15.0x 10.8xmedian 15.0x
P/FCF now vs peer median 25.4xmedian 21.7x -442.0xmedian 21.7x 13.1xmedian 21.7x
P/B now vs peer median 5.4xmedian 2.2x 254.8xmedian 2.2x 3.7xmedian 2.2x
PEG now vs peer median 1.35median 0.35 —median 0.35 0.08median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAZNRGCAUPH
Revenue $58.67B – $311.51M
Gross profit $50.25B – $281.47M
Operating income $13.97B – $150.75M
Net income $10.45B – $314.11M
Free cash flow $10.67B – $175.07M
R&D $15.07B – $39.85M
EPS (diluted) $6.69 – $2.35
Cash & equivalents $4.90B $14.19M $179.83M
Total debt $32.35B $21.88K –
Shares (diluted) 1.56B 494.60M 133.53M
Enterprise value $244.25B $3.37B $715.62M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAZNRGCAUPH
P/E 25.9x -290.0x 7.1x
P/FCF 25.4x -442.0x 13.1x
P/Operating cash flow 19.7x – 13.1x
P/S 4.6x – 7.3x
P/B 5.4x 254.8x 3.7x
P/Tangible book 21.4x 254.8x 3.7x
EV/EBITDA 14.7x – 10.8x
EV/EBIT 21.3x – 12.2x
EV/Revenue 5.1x – 5.9x
EV/FCF 27.9x – 10.5x
EV/Operating cash flow 21.7x – 10.5x
PEG (3Y EPS CAGR) 1.35 – 0.08

Growth

14 metrics
MetricAZNRGCAUPH
Revenue growth (1Y) 9.4% – 19.8%
Revenue CAGR (3Y) 10.6% – 24.8%
Gross profit growth (1Y) 9.3% – 20.9%
Gross profit CAGR (3Y) 13.1% – 22.2%
Operating income growth (1Y) 23.4% – 189.8%
Operating income CAGR (3Y) 23.9% – 56.2%
Net income growth (1Y) 25.9% – 418.0%
Net income CAGR (3Y) 19.2% – 84.9%
EPS growth (1Y) 26.0% – 433.5%
EPS CAGR (3Y) 19.2% – 87.7%
Operating cash flow growth (1Y) 2.3% – 89.1%
Operating cash flow CAGR (3Y) 13.7% – 86.1%
Free cash flow growth (1Y) -4.5% – 89.4%
Free cash flow CAGR (3Y) 8.5% – 85.3%

Profitability

14 metrics
MetricAZNRGCAUPH
Gross margin 85.6% – 90.4%
EBITDA margin 34.6% – 54.6%
Operating margin 23.8% – 48.4%
Pretax margin 21.5% – 51.5%
Net margin 17.8% – 100.8%
FCF margin 18.2% – 56.2%
Operating cash flow margin 23.3% – 56.3%
Return on equity 21.4% – 53.1%
Return on assets 9.1% – 41.4%
Return on invested capital 23.3% – –
Return on capital employed 16.8% – 22.9%
Asset turnover 0.5x – 0.4x
Cash conversion (OCF / net income) 1.3x – 0.6x
Stock comp / revenue – – 4.7%

Financial Health

11 metrics
MetricAZNRGCAUPH
Debt / assets 27.9% 0.1% –
Debt / equity 0.6x 0.0x –
Net debt / EBITDA 1.4x – –
Debt / FCF 3.0x – –
Liabilities / assets 56.5% 9.4% 22.4%
Equity / assets 43.5% 90.6% 77.6%
Interest coverage 15.9x – 36.7x
Current ratio 0.9x 10.8x 5.4x
Quick ratio 0.7x 10.7x 4.8x
Cash ratio 0.2x 10.7x 4.4x
Altman Z-score 3.50 – 8.41

Shareholder Returns

7 metrics
MetricAZNRGCAUPH
Dividend yield 1.4% – –
Net buyback yield 0.0% – 0.9%
Shareholder yield 1.4% 0.0% 0.9%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAZNRGCAUPH
Forward P/E 17.5xFY2026 – 17.9xFY2026
EPS, next fiscal year $10.00FY2026 – $0.96FY2026
EPS growth, next FY +9.2%FY2026 – -53.6%FY2026
EPS growth, the year after +6.1% – +14.6%
Revenue, next fiscal year $59.02BFY2026 – $348.13MFY2026
Revenue growth, next FY +0.5%FY2026 – +23.0%FY2026
Revenue growth, the year after +8.0% – +6.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAZNRGCAUPH
Held by institutions 52.1% 0.3% 58.7%
Institutions holding 1,497 36 281
Change in shares held, QoQ +7.8% +117.0% +5.4%
Institutions buying 809 28 156
Institutions selling 468 5 79
Buyers to sellers 1.73 5.60 1.97

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AZNRGCAUPH
AZN 1.00 0.04 0.22
RGC 0.04 1.00 0.06
AUPH 0.22 0.06 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, AZN, RGC and AUPH?

Astrazeneca (AZN) is the largest by market capitalisation: Astrazeneca (AZN) $270.49B, Regencell Bioscience Holdings (RGC) $3.40B, Aurinia Pharmaceuticals (AUPH) $2.29B.

Which stock is cheaper, AZN, RGC and AUPH?

Aurinia Pharmaceuticals (AUPH) trades on the lowest price-to-earnings ratio (Astrazeneca (AZN) 25.9x, Regencell Bioscience Holdings (RGC) -290.0x, Aurinia Pharmaceuticals (AUPH) 7.1x). On next year's consensus earnings, Astrazeneca (AZN) is cheapest (Astrazeneca (AZN) 17.5x, Aurinia Pharmaceuticals (AUPH) 17.9x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Aurinia Pharmaceuticals (AUPH) grew revenue fastest over the trailing twelve months: Astrazeneca (AZN) +9.4%, Aurinia Pharmaceuticals (AUPH) +19.8%.

Which company is more profitable?

Aurinia Pharmaceuticals (AUPH) has the highest net margin (Astrazeneca (AZN) 17.8%, Aurinia Pharmaceuticals (AUPH) 100.8%).

Which stock has performed better?

Over the past year Aurinia Pharmaceuticals (AUPH) returned the most: Astrazeneca (AZN) +6.1%, Regencell Bioscience Holdings (RGC) -58.7%, Aurinia Pharmaceuticals (AUPH) +40.8%. Over five years, Regencell Bioscience Holdings (RGC) compounded fastest (Astrazeneca (AZN) +6.9%/yr, Regencell Bioscience Holdings (RGC) +81.0%/yr, Aurinia Pharmaceuticals (AUPH) -12.3%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Astrazeneca (AZN) 1.37%, Regencell Bioscience Holdings (RGC) 0.00%. Regencell Bioscience Holdings (RGC) and Aurinia Pharmaceuticals (AUPH) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Astrazeneca (AZN) has been the steadiest (Astrazeneca (AZN) 27.5%, Regencell Bioscience Holdings (RGC) 142.7%, Aurinia Pharmaceuticals (AUPH) 37.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, AZN, RGC and AUPH?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Aurinia Pharmaceuticals (AUPH) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.