AZN vs MRK Stock Comparison

Astrazeneca and Merck Prices as of Oct 23, 2026 Peers: Industry group
AZN Astrazeneca Plc
$171.47 +5.0% 1M +2.8% 1Y
Market cap
$266.58B
P/E
25.5x
Revenue (TTM)
$58.67B
Div. yield
–
Pharmaceuticals Healthcare
8 wins
MRK Merck & Co., Inc.
$145.28 -1.9% 1M +66.6% 1Y
Market cap
$346.73B
P/E
109.3x
Revenue (TTM)
$66.57B
Div. yield
0.02%
Pharmaceuticals Healthcare
3 wins

Head to Head

11 decided of 12

Astrazeneca leads on 8 of the 12 questions below (Astrazeneca 8, Merck 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAZNMRKLeader
Larger companyMarket capitalisation $266.58B $346.73B MRK
Cheaper on earningsLower P/E, profitable companies only 25.5x 109.3x AZN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 17.1x 58.3x AZN
Faster revenue growthRevenue growth, trailing twelve months +9.4% +4.6% AZN
More profitableNet margin, trailing twelve months 17.8% 4.8% AZN
Better return on capitalReturn on invested capital 23.3% 3.6% AZN
Less leveragedLower net debt / EBITDA 1.4x 3.6x AZN
Higher dividend yieldTrailing dividend yield 0.00% 0.02% –
Better 1-year returnPrice return, last 12 months +2.8% +66.6% MRK
Better 5-year returnAnnualised price return, 5 years +6.8%/yr +12.4%/yr MRK
Less volatileAnnualised volatility, 1 year 27.4% 29.4% AZN
Higher overall scoreMean of the five percentile scores vs peers 70/100 61/100 AZN

Percentile Scorecard

AZNMRK

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAZNMRK
Valuation 85 #94 of 624 79 #134 of 624
Growth 69 #185 of 603 36 #387 of 603
Profitability 94 #34 of 555 91 #53 of 555
Financial Health 36 #424 of 657 20 #528 of 657
Shareholder Returns 68 #120 of 370 81 #71 of 370
Overall 70 61
  • AZN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • MRK ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAZNMRKSPY
1 month +5.0%-1.9% -1.0%
3 months +1.4%+10.8% +2.9%
6 months -9.6%+29.8% +6.4%
Year to date -6.7%+38.0% +11.4%
1 year +2.8%+66.6% +13.1%
3 years +32.8%+41.0% +79.4%
3 years, per year +9.9%+12.1% +21.5%
5 years +38.8%+79.0% +67.7%
5 years, per year +6.8%+12.4% +10.9%
10 years +179.1%+137.4% +255.2%
10 years, per year +10.8%+9.0% +13.5%

Risk

MeasureAZNMRKSPY
Volatility, 1Y 27.4%29.4% 12.7%
Downside volatility, 1Y 27.2%24.2% 12.7%
Beta vs S&P 500, 1Y 0.220.13 1.00
Return / volatility, 1Y 0.102.27 1.03
Max drawdown, 5Y -27.9%-44.7% -25.4%
From 52-week high -18.1%-7.1% -2.5%
52-week high $209.48$156.45 $779.14
52-week low $155.60$82.49 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAZNMRK
P/E now vs peer median 25.4xmedian 17.2x 113.1xmedian 17.2x
P/S now vs peer median 4.5xmedian 8.8x 5.4xmedian 8.8x
EV/EBITDA now vs peer median 14.4xmedian 16.0x 30.9xmedian 16.0x
P/FCF now vs peer median 24.9xmedian 17.8x 22.3xmedian 17.8x
P/B now vs peer median 5.3xmedian 2.1x 8.5xmedian 2.1x
PEG now vs peer median 1.33median 0.32 71.19median 0.32

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAZNMRK
Revenue $58.67B $66.57B
Gross profit $50.25B $48.57B
Operating income $13.97B $6.38B
Net income $10.45B $3.17B
Free cash flow $10.67B $16.06B
R&D $15.07B $30.45B
EPS (diluted) $6.69 $1.28
Cash & equivalents $4.90B $6.85B
Total debt $106.76B $193.74B
Shares (diluted) 1.56B 2.47B
Enterprise value $240.27B $301.10B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAZNMRK
P/E 25.4x 113.1x
P/FCF 24.9x 22.3x
P/Operating cash flow 19.4x 18.0x
P/S 4.5x 5.4x
P/B 5.3x 8.5x
P/Tangible book 21.0x 21.1x
EV/EBITDA 14.4x 30.9x
EV/EBIT 21.0x 63.5x
EV/Revenue 5.0x 6.1x
EV/FCF 27.5x 25.2x
EV/Operating cash flow 21.4x 20.3x
PEG (3Y EPS CAGR) 1.33 71.19

Growth

14 metrics
MetricAZNMRK
Revenue growth (1Y) 9.4% 4.6%
Revenue CAGR (3Y) 10.6% 4.5%
Gross profit growth (1Y) 9.3% -0.3%
Gross profit CAGR (3Y) 13.1% 4.5%
Operating income growth (1Y) 23.4% -66.6%
Operating income CAGR (3Y) 23.9% 1.9%
Net income growth (1Y) 25.9% -80.7%
Net income CAGR (3Y) 19.2% 0.5%
EPS growth (1Y) 26.0% -80.3%
EPS CAGR (3Y) 19.2% 1.6%
Operating cash flow growth (1Y) 2.3% 7.7%
Operating cash flow CAGR (3Y) 13.7% 9.8%
Free cash flow growth (1Y) -4.5% 9.1%
Free cash flow CAGR (3Y) 8.5% 14.0%

Profitability

14 metrics
MetricAZNMRK
Gross margin 85.6% 73.0%
EBITDA margin 34.6% 19.7%
Operating margin 23.8% 9.6%
Pretax margin 21.5% 8.9%
Net margin 17.8% 4.8%
FCF margin 18.2% 24.1%
Operating cash flow margin 23.3% 30.0%
Return on equity 21.4% 7.2%
Return on assets 9.1% 2.5%
Return on invested capital 23.3% 3.6%
Return on capital employed 16.8% 6.3%
Asset turnover 0.5x 0.5x
Cash conversion (OCF / net income) 1.3x 6.3x
Stock comp / revenue – 1.3%

Financial Health

11 metrics
MetricAZNMRK
Debt / assets 27.9% 41.5%
Debt / equity 0.6x 1.3x
Net debt / EBITDA 1.4x 3.6x
Debt / FCF 3.0x 3.4x
Liabilities / assets 56.5% 67.7%
Equity / assets 43.5% 32.3%
Interest coverage 15.9x –
Current ratio 0.9x 1.3x
Quick ratio 0.7x 0.7x
Cash ratio 0.2x 0.3x
Altman Z-score 3.46 3.89

Shareholder Returns

7 metrics
MetricAZNMRK
Dividend yield 1.4% 2.3%
Net buyback yield 0.0% 1.1%
Shareholder yield 1.4% 3.4%
Payout ratio (earnings) – 261.8%
Payout ratio (FCF) – 51.7%
Dividend growth (1Y) – 3.3%
Dividend CAGR (3Y) – 4.7%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAZNMRK
Forward P/E 17.1xFY2026 58.3xFY2026
EPS, next fiscal year $10.00FY2026 $2.49FY2026
EPS growth, next FY +9.2%FY2026 -72.3%FY2026
EPS growth, the year after +6.2% +257.4%
Revenue, next fiscal year $59.09BFY2026 $69.45BFY2026
Revenue growth, next FY +0.6%FY2026 +6.8%FY2026
Revenue growth, the year after +7.7% -3.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAZNMRK
Held by institutions 52.1% 79.9%
Institutions holding 1,496 3,794
Change in shares held, QoQ +7.8% +2.6%
Institutions buying 808 1,840
Institutions selling 468 1,464
Buyers to sellers 1.73 1.26

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AZNMRK
AZN 1.00 0.50
MRK 0.50 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, AZN and MRK?

Merck (MRK) is the largest by market capitalisation: Astrazeneca (AZN) $266.58B, Merck (MRK) $346.73B.

Which stock is cheaper, AZN and MRK?

Astrazeneca (AZN) trades on the lowest price-to-earnings ratio (Astrazeneca (AZN) 25.5x, Merck (MRK) 109.3x). On next year's consensus earnings, Astrazeneca (AZN) is cheapest (Astrazeneca (AZN) 17.1x, Merck (MRK) 58.3x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Astrazeneca (AZN) grew revenue fastest over the trailing twelve months: Astrazeneca (AZN) +9.4%, Merck (MRK) +4.6%.

Which company is more profitable?

Astrazeneca (AZN) has the highest net margin (Astrazeneca (AZN) 17.8%, Merck (MRK) 4.8%). On return on invested capital, Astrazeneca (AZN) leads (Astrazeneca (AZN) 23.3%, Merck (MRK) 3.6%).

Which stock has performed better?

Over the past year Merck (MRK) returned the most: Astrazeneca (AZN) +2.8%, Merck (MRK) +66.6%. Over five years, Merck (MRK) compounded fastest (Astrazeneca (AZN) +6.8%/yr, Merck (MRK) +12.4%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Astrazeneca (AZN) 0.00%, Merck (MRK) 0.02%. Astrazeneca (AZN) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Astrazeneca (AZN) has been the steadiest (Astrazeneca (AZN) 27.4%, Merck (MRK) 29.4%). Volatility measures how widely the price swings, not the risk of the business.

Do AZN and MRK move together?

Their daily returns over the past year have a correlation of 0.50, a moderate positive relationship. Holding both diversifies more than two closely linked stocks would.

Which is the better stock, AZN and MRK?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Astrazeneca (AZN) leads on 8. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.