AZN vs OGN vs PFE Stock Comparison

Astrazeneca, Organon and Pfizer Prices as of Oct 26, 2026 Peers: Industry group
AZN Astrazeneca Plc
$172.00 +3.2% 1M +3.3% 1Y
Market cap
$263.55B
P/E
25.2x
Revenue (TTM)
$58.67B
Div. yield
–
Pharmaceuticals Healthcare
7 wins
OGN Organon & Co.
$13.76 +0.2% 1M +50.2% 1Y
Market cap
$3.61B
P/E
17.3x
Revenue (TTM)
$6.13B
Div. yield
–
Pharmaceuticals Healthcare
3 wins
PFE Pfizer Inc
$29.79 +3.9% 1M +20.3% 1Y
Market cap
$169.97B
P/E
39.2x
Revenue (TTM)
$63.70B
Div. yield
0.06%
Pharmaceuticals Healthcare
1 win

Head to Head

11 decided of 12

Astrazeneca leads on 7 of the 12 questions below (Astrazeneca 7, Organon 3, Pfizer 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAZNOGNPFELeader
Larger companyMarket capitalisation $263.55B $3.61B $169.97B AZN
Cheaper on earningsLower P/E, profitable companies only 25.2x 17.3x 39.2x OGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 17.2x 3.9x 10.5x OGN
Faster revenue growthRevenue growth, trailing twelve months +9.4% -2.5% -0.2% AZN
More profitableNet margin, trailing twelve months 17.8% 3.4% 6.8% AZN
Better return on capitalReturn on invested capital 23.3% 5.0% 13.4% AZN
Less leveragedLower net debt / EBITDA 1.4x 5.0x 1.9x AZN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.06% –
Better 1-year returnPrice return, last 12 months +3.3% +50.2% +20.3% OGN
Better 5-year returnAnnualised price return, 5 years +6.8%/yr -17.4%/yr -7.1%/yr AZN
Less volatileAnnualised volatility, 1 year 27.4% 56.9% 21.7% PFE
Higher overall scoreMean of the five percentile scores vs peers 71/100 55/100 65/100 AZN

Percentile Scorecard

AZNOGNPFE

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAZNOGNPFE
Valuation 85 #96 of 626 99 #10 of 626 94 #37 of 626
Growth 70 #185 of 604 23 #467 of 604 23 #466 of 604
Profitability 94 #35 of 555 87 #71 of 555 92 #46 of 555
Financial Health 36 #421 of 658 17 #549 of 658 24 #502 of 658
Shareholder Returns 70 #112 of 368 49 #189 of 368 91 #35 of 368
Overall 71 55 65
  • AZN ranked among 673 companies in Pharmaceuticals and Biotechnology
  • OGN ranked among 673 companies in Pharmaceuticals and Biotechnology
  • PFE ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAZNOGNPFESPY
1 month +3.2%+0.2%+3.9% -0.8%
3 months +1.4%+1.7%+20.8% +3.5%
6 months -8.3%+4.6%+11.2% +7.0%
Year to date -6.5%+91.9%+19.6% +12.2%
1 year +3.3%+50.2%+20.3% +13.0%
3 years +39.0%-8.0%-1.1% +86.3%
3 years, per year +11.6%-2.8%-0.4% +23.1%
5 years +39.2%-61.5%-30.7% +68.6%
5 years, per year +6.8%-17.4%-7.1% +11.0%
10 years +190.6%—-8.1% +258.0%
10 years, per year +11.3%—-0.8% +13.6%

Risk

MeasureAZNOGNPFESPY
Volatility, 1Y 27.4%56.9%21.7% 12.7%
Downside volatility, 1Y 27.3%39.4%21.1% 12.7%
Beta vs S&P 500, 1Y 0.220.760.23 1.00
Return / volatility, 1Y 0.120.880.94 1.02
Max drawdown, 5Y -27.9%-85.5%-64.8% -25.4%
From 52-week high -17.9%-0.4%-2.0% -1.8%
52-week high $209.48$13.81$30.41 $779.14
52-week low $155.60$5.70$23.67 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAZNOGNPFE
P/E now vs peer median 25.5xmedian 17.1x 17.3xmedian 17.1x 39.2xmedian 17.1x
P/S now vs peer median 4.5xmedian 8.8x 0.6xmedian 8.8x 2.7xmedian 8.8x
EV/EBITDA now vs peer median 14.5xmedian 17.1x 7.5xmedian 17.1x 8.2xmedian 17.1x
P/FCF now vs peer median 25.0xmedian 18.0x 6.4xmedian 18.0x 15.5xmedian 18.0x
P/B now vs peer median 5.3xmedian 2.1x 3.6xmedian 2.1x 2.0xmedian 2.1x
PEG now vs peer median 1.33median 0.31 -0.48median 0.31 -0.95median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAZNOGNPFE
Revenue $58.67B $6.13B $63.70B
Gross profit $50.25B $3.23B $46.61B
Operating income $13.97B $1.13B $20.39B
Net income $10.45B $209.00M $4.36B
Free cash flow $10.67B $567.00M $10.99B
R&D $15.07B $358.00M $11.05B
EPS (diluted) $6.69 $0.77 $0.76
Cash & equivalents $4.90B $1.13B $976.00M
Total debt $106.76B $8.55B $63.19B
Shares (diluted) 1.56B 270.45M 5.70B
Enterprise value $237.24B $115.59M $116.62B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAZNOGNPFE
P/E 25.5x 17.3x 39.2x
P/FCF 25.0x 6.4x 15.5x
P/Operating cash flow 19.5x 4.9x 12.7x
P/S 4.5x 0.6x 2.7x
P/B 5.3x 3.6x 2.0x
P/Tangible book 21.1x -34.1x 4.4x
EV/EBITDA 14.5x 7.5x 8.2x
EV/EBIT 21.0x 9.8x 10.9x
EV/Revenue 5.0x 1.8x 3.5x
EV/FCF 27.6x 19.5x 20.1x
EV/Operating cash flow 21.5x 15.0x 16.5x
PEG (3Y EPS CAGR) 1.33 -0.48 -0.95

Growth

14 metrics
MetricAZNOGNPFE
Revenue growth (1Y) 9.4% -2.5% -0.2%
Revenue CAGR (3Y) 10.6% -0.2% -7.0%
Gross profit growth (1Y) 9.3% -8.7% 1.2%
Gross profit CAGR (3Y) 13.1% -5.3% -5.6%
Operating income growth (1Y) 23.4% -9.3% 1.5%
Operating income CAGR (3Y) 23.9% -8.1% -9.9%
Net income growth (1Y) 25.9% -70.1% -59.6%
Net income CAGR (3Y) 19.2% -34.8% -41.3%
EPS growth (1Y) 26.0% -71.3% -59.7%
EPS CAGR (3Y) 19.2% -36.0% -41.3%
Operating cash flow growth (1Y) 2.3% -10.8% -11.8%
Operating cash flow CAGR (3Y) 13.7% 0.5% -2.7%
Free cash flow growth (1Y) -4.5% -13.8% -11.7%
Free cash flow CAGR (3Y) 8.5% 5.0% 1.0%

Profitability

14 metrics
MetricAZNOGNPFE
Gross margin 85.6% 52.7% 73.2%
EBITDA margin 34.6% 24.2% 42.4%
Operating margin 23.8% 18.4% 32.0%
Pretax margin 21.5% 8.0% 6.6%
Net margin 17.8% 3.4% 6.8%
FCF margin 18.2% 9.3% 17.2%
Operating cash flow margin 23.3% 12.0% 21.0%
Return on equity 21.4% 21.9% 5.0%
Return on assets 9.1% 1.6% 2.1%
Return on invested capital 23.3% 5.0% 13.4%
Return on capital employed 16.8% 10.8% 11.9%
Asset turnover 0.5x 0.5x 0.3x
Cash conversion (OCF / net income) 1.3x 3.5x 3.1x
Stock comp / revenue – 1.2% 1.5%

Financial Health

11 metrics
MetricAZNOGNPFE
Debt / assets 27.9% 64.9% 31.4%
Debt / equity 0.6x 8.5x 0.7x
Net debt / EBITDA 1.4x 5.0x 1.9x
Debt / FCF 3.0x 15.1x 5.8x
Liabilities / assets 56.5% 92.4% 57.5%
Equity / assets 43.5% 7.6% 42.5%
Interest coverage 15.9x 2.4x –
Current ratio 0.9x 2.0x 1.3x
Quick ratio 0.7x 1.0x 0.7x
Cash ratio 0.2x 0.4x 0.4x
Altman Z-score 3.46 1.30 2.36

Shareholder Returns

7 metrics
MetricAZNOGNPFE
Dividend yield 1.4% 0.6% 5.8%
Net buyback yield 0.0% – –
Shareholder yield 1.4% 0.6% 5.8%
Payout ratio (earnings) – – 224.5%
Payout ratio (FCF) – – 89.1%
Dividend growth (1Y) – – 1.5%
Dividend CAGR (3Y) – – 2.4%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAZNOGNPFE
Forward P/E 17.2xFY2026 3.9xFY2026 10.5xFY2026
EPS, next fiscal year $10.00FY2026 $3.56FY2026 $2.85FY2026
EPS growth, next FY +9.2%FY2026 -2.7%FY2026 -11.5%FY2026
EPS growth, the year after +6.1% 0.0% -4.6%
Revenue, next fiscal year $59.02BFY2026 $5.89BFY2026 $60.59BFY2026
Revenue growth, next FY +0.5%FY2026 -5.3%FY2026 -3.2%FY2026
Revenue growth, the year after +8.0% +3.0% +3.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAZNOGNPFE
Held by institutions 52.1% 84.3% 66.9%
Institutions holding 1,496 631 2,835
Change in shares held, QoQ +7.8% +10.8% +2.0%
Institutions buying 808 244 1,324
Institutions selling 468 186 1,204
Buyers to sellers 1.73 1.31 1.10

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AZNOGNPFE
AZN 1.00 0.06 0.42
OGN 0.06 1.00 0.06
PFE 0.42 0.06 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, AZN, OGN and PFE?

Astrazeneca (AZN) is the largest by market capitalisation: Astrazeneca (AZN) $263.55B, Organon (OGN) $3.61B, Pfizer (PFE) $169.97B.

Which stock is cheaper, AZN, OGN and PFE?

Organon (OGN) trades on the lowest price-to-earnings ratio (Astrazeneca (AZN) 25.2x, Organon (OGN) 17.3x, Pfizer (PFE) 39.2x). On next year's consensus earnings, Organon (OGN) is cheapest (Astrazeneca (AZN) 17.2x, Organon (OGN) 3.9x, Pfizer (PFE) 10.5x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Astrazeneca (AZN) grew revenue fastest over the trailing twelve months: Astrazeneca (AZN) +9.4%, Organon (OGN) -2.5%, Pfizer (PFE) -0.2%.

Which company is more profitable?

Astrazeneca (AZN) has the highest net margin (Astrazeneca (AZN) 17.8%, Organon (OGN) 3.4%, Pfizer (PFE) 6.8%). On return on invested capital, Astrazeneca (AZN) leads (Astrazeneca (AZN) 23.3%, Organon (OGN) 5.0%, Pfizer (PFE) 13.4%).

Which stock has performed better?

Over the past year Organon (OGN) returned the most: Astrazeneca (AZN) +3.3%, Organon (OGN) +50.2%, Pfizer (PFE) +20.3%. Over five years, Astrazeneca (AZN) compounded fastest (Astrazeneca (AZN) +6.8%/yr, Organon (OGN) -17.4%/yr, Pfizer (PFE) -7.1%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Astrazeneca (AZN) 0.00%, Organon (OGN) 0.00%, Pfizer (PFE) 0.06%. Astrazeneca (AZN) and Organon (OGN) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Pfizer (PFE) has been the steadiest (Astrazeneca (AZN) 27.4%, Organon (OGN) 56.9%, Pfizer (PFE) 21.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, AZN, OGN and PFE?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Astrazeneca (AZN) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.