AZN vs AUPH vs NUVB Stock Comparison

Astrazeneca, Aurinia Pharmaceuticals and Nuvation Bio Prices as of Oct 27, 2026 Peers: Industry group
AZN Astrazeneca Plc
$170.02 +2.1% 1M +1.1% 1Y
Market cap
$263.53B
P/E
25.2x
Revenue (TTM)
$58.67B
Div. yield
1.41%
Pharmaceuticals Healthcare
5 wins
NUVB Nuvation Bio Inc.
$4.54 -20.6% 1M -9.9% 1Y
Market cap
$1.57B
P/E
–
Revenue (TTM)
$169.90M
Div. yield
–
Pharmaceuticals Healthcare
1 win

Head to Head

10 decided of 12

Astrazeneca leads on 5 of the 12 questions below (Astrazeneca 5, Aurinia Pharmaceuticals 4, Nuvation Bio 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAZNAUPHNUVBLeader
Larger companyMarket capitalisation $263.53B $2.29B $1.57B AZN
Cheaper on earningsLower P/E, profitable companies only 25.2x 7.1x -10.6x AUPH
Cheaper on forward earningsLower price / next fiscal year consensus EPS 17.0x 18.0x — AZN
Faster revenue growthRevenue growth, trailing twelve months +9.4% +19.8% +1,083.6% NUVB
More profitableNet margin, trailing twelve months 17.8% 100.8% -88.2% AUPH
Better return on capitalReturn on invested capital 23.3% — — –
Less leveragedLower net debt / EBITDA 1.4x — 4.9x AZN
Higher dividend yieldTrailing dividend yield 1.41% — — –
Better 1-year returnPrice return, last 12 months +1.1% +40.4% -9.9% AUPH
Better 5-year returnAnnualised price return, 5 years +6.5%/yr -10.5%/yr -13.7%/yr AZN
Less volatileAnnualised volatility, 1 year 27.4% 37.3% 79.1% AZN
Higher overall scoreMean of the five percentile scores vs peers 71/100 90/100 63/100 AUPH

Percentile Scorecard

AZNAUPHNUVB

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAZNAUPHNUVB
Valuation 86 #91 of 625 93 #46 of 625 59 #256 of 625
Growth 70 #183 of 602 96 #25 of 602 61 #236 of 602
Profitability 94 #34 of 551 97 #17 of 551 65 #192 of 551
Financial Health 36 #420 of 656 74 #174 of 656 67 #218 of 656
Shareholder Returns 70 #111 of 365 92 #31 of 365 64 #131 of 365
Overall 71 90 63
  • AZN ranked among 672 companies in Pharmaceuticals and Biotechnology
  • AUPH ranked among 672 companies in Pharmaceuticals and Biotechnology
  • NUVB ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAZNAUPHNUVBSPY
1 month +2.1%+4.9%-20.6% -0.2%
3 months -1.4%+15.3%-32.2% +3.9%
6 months -8.9%+7.5%-0.4% +8.2%
Year to date -7.5%+8.2%-49.3% +12.9%
1 year +1.1%+40.4%-9.9% +12.3%
3 years +37.4%+139.9%+345.1% +87.4%
3 years, per year +11.2%+33.9%+64.6% +23.3%
5 years +36.7%-42.4%-52.2% +67.9%
5 years, per year +6.5%-10.5%-13.7% +10.9%
10 years +197.9%+444.2%— +261.1%
10 years, per year +11.5%+18.5%— +13.7%

Risk

MeasureAZNAUPHNUVBSPY
Volatility, 1Y 27.4%37.3%79.1% 12.7%
Downside volatility, 1Y 27.2%34.0%76.7% 12.7%
Beta vs S&P 500, 1Y 0.210.541.64 1.00
Return / volatility, 1Y 0.041.08-0.13 0.97
Max drawdown, 5Y -27.9%-87.6%-90.4% -25.4%
From 52-week high -18.8%-7.4%-52.4% -1.2%
52-week high $209.48$18.62$9.54 $779.14
52-week low $155.60$12.12$4.05 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAZNAUPHNUVB
P/E now vs peer median 25.2xmedian 17.2x 7.1xmedian 17.2x -10.6xmedian 17.2x
P/S now vs peer median 4.5xmedian 9.0x 7.4xmedian 9.0x 9.3xmedian 9.0x
EV/EBITDA now vs peer median 14.3xmedian 16.3x 10.9xmedian 16.3x -6.8xmedian 16.3x
P/FCF now vs peer median 24.7xmedian 18.7x 13.1xmedian 18.7x -12.2xmedian 18.7x
P/B now vs peer median 5.2xmedian 2.2x 3.7xmedian 2.2x 6.2xmedian 2.2x
PEG now vs peer median 1.31median 0.33 0.08median 0.33 8.07median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAZNAUPHNUVB
Revenue $58.67B $311.51M $169.90M
Gross profit $50.25B $281.47M –
Operating income $13.97B $150.75M -$137.63M
Net income $10.45B $314.11M -$149.83M
Free cash flow $10.67B $175.07M -$128.93M
R&D $15.07B $39.85M $128.85M
EPS (diluted) $6.69 $2.35 $-0.43
Cash & equivalents $4.90B $179.83M $258.60M
Total debt $32.35B – $5.89M
Shares (diluted) 1.56B 133.53M 348.77M
Enterprise value $237.29B $720.93M -$699.81M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAZNAUPHNUVB
P/E 25.2x 7.1x -10.6x
P/FCF 24.7x 13.1x -12.2x
P/Operating cash flow 19.2x 13.1x -13.1x
P/S 4.5x 7.4x 9.3x
P/B 5.2x 3.7x 6.2x
P/Tangible book 20.8x 3.7x 6.5x
EV/EBITDA 14.3x 10.9x -6.8x
EV/EBIT 20.8x 12.3x -6.7x
EV/Revenue 5.0x 5.9x 5.4x
EV/FCF 27.3x 10.6x -7.1x
EV/Operating cash flow 21.2x 10.6x -7.6x
PEG (3Y EPS CAGR) 1.31 0.08 8.07

Growth

14 metrics
MetricAZNAUPHNUVB
Revenue growth (1Y) 9.4% 19.8% 1,084%
Revenue CAGR (3Y) 10.6% 24.8% –
Gross profit growth (1Y) 9.3% 20.9% –
Gross profit CAGR (3Y) 13.1% 22.2% –
Operating income growth (1Y) 23.4% 189.8% 38.7%
Operating income CAGR (3Y) 23.9% 56.2% -9.0%
Net income growth (1Y) 25.9% 418.0% 26.2%
Net income CAGR (3Y) 19.2% 84.9% -18.3%
EPS growth (1Y) 26.0% 433.5% 27.9%
EPS CAGR (3Y) 19.2% 87.7% -1.3%
Operating cash flow growth (1Y) 2.3% 89.1% 28.3%
Operating cash flow CAGR (3Y) 13.7% 86.1% -14.1%
Free cash flow growth (1Y) -4.5% 89.4% 23.5%
Free cash flow CAGR (3Y) 8.5% 85.3% -16.6%

Profitability

14 metrics
MetricAZNAUPHNUVB
Gross margin 85.6% 90.4% –
EBITDA margin 34.6% 54.6% -79.0%
Operating margin 23.8% 48.4% -81.0%
Pretax margin 21.5% 51.5% -88.2%
Net margin 17.8% 100.8% -88.2%
FCF margin 18.2% 56.2% -75.9%
Operating cash flow margin 23.3% 56.3% -70.9%
Return on equity 21.4% 53.1% -52.3%
Return on assets 9.1% 41.4% -22.1%
Return on invested capital 23.3% – –
Return on capital employed 16.8% 22.9% -23.3%
Asset turnover 0.5x 0.4x 0.3x
Cash conversion (OCF / net income) 1.3x 0.6x 0.8x
Stock comp / revenue – 4.7% 20.9%

Financial Health

11 metrics
MetricAZNAUPHNUVB
Debt / assets 27.9% – 0.8%
Debt / equity 0.6x – 0.0x
Net debt / EBITDA 1.4x – 4.9x
Debt / FCF 3.0x – 0.0x
Liabilities / assets 56.5% 22.4% 65.9%
Equity / assets 43.5% 77.6% 34.1%
Interest coverage 15.9x 36.7x -5.2x
Current ratio 0.9x 5.4x 8.4x
Quick ratio 0.7x 4.8x 7.9x
Cash ratio 0.2x 4.4x 7.6x
Altman Z-score 3.43 8.42 0.37

Shareholder Returns

7 metrics
MetricAZNAUPHNUVB
Dividend yield 1.4% – –
Net buyback yield 0.0% 0.9% -0.7%
Shareholder yield 1.4% 0.9% -0.7%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAZNAUPHNUVB
Forward P/E 17.0xFY2026 18.0xFY2026 –
EPS, next fiscal year $10.00FY2026 $0.96FY2026 $-0.38FY2026
EPS growth, next FY +9.2%FY2026 -53.6%FY2026 –
EPS growth, the year after +6.1% +14.6% –
Revenue, next fiscal year $59.02BFY2026 $348.13MFY2026 $187.51MFY2026
Revenue growth, next FY +0.5%FY2026 +23.0%FY2026 +198.1%FY2026
Revenue growth, the year after +8.0% +6.9% +52.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAZNAUPHNUVB
Held by institutions 52.1% 58.7% 66.6%
Institutions holding 1,496 280 238
Change in shares held, QoQ +7.8% +5.4% +5.7%
Institutions buying 808 156 148
Institutions selling 468 78 50
Buyers to sellers 1.73 2.00 2.96

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AZNAUPHNUVB
AZN 1.00 0.23 0.15
AUPH 0.23 1.00 0.19
NUVB 0.15 0.19 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, AZN, AUPH and NUVB?

Astrazeneca (AZN) is the largest by market capitalisation: Astrazeneca (AZN) $263.53B, Aurinia Pharmaceuticals (AUPH) $2.29B, Nuvation Bio (NUVB) $1.57B.

Which stock is cheaper, AZN, AUPH and NUVB?

Aurinia Pharmaceuticals (AUPH) trades on the lowest price-to-earnings ratio (Astrazeneca (AZN) 25.2x, Aurinia Pharmaceuticals (AUPH) 7.1x, Nuvation Bio (NUVB) -10.6x). On next year's consensus earnings, Astrazeneca (AZN) is cheapest (Astrazeneca (AZN) 17.0x, Aurinia Pharmaceuticals (AUPH) 18.0x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Nuvation Bio (NUVB) grew revenue fastest over the trailing twelve months: Astrazeneca (AZN) +9.4%, Aurinia Pharmaceuticals (AUPH) +19.8%, Nuvation Bio (NUVB) +1,083.6%.

Which company is more profitable?

Aurinia Pharmaceuticals (AUPH) has the highest net margin (Astrazeneca (AZN) 17.8%, Aurinia Pharmaceuticals (AUPH) 100.8%, Nuvation Bio (NUVB) -88.2%).

Which stock has performed better?

Over the past year Aurinia Pharmaceuticals (AUPH) returned the most: Astrazeneca (AZN) +1.1%, Aurinia Pharmaceuticals (AUPH) +40.4%, Nuvation Bio (NUVB) -9.9%. Over five years, Astrazeneca (AZN) compounded fastest (Astrazeneca (AZN) +6.5%/yr, Aurinia Pharmaceuticals (AUPH) -10.5%/yr, Nuvation Bio (NUVB) -13.7%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Astrazeneca (AZN) 1.41%. Aurinia Pharmaceuticals (AUPH) and Nuvation Bio (NUVB) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Astrazeneca (AZN) has been the steadiest (Astrazeneca (AZN) 27.4%, Aurinia Pharmaceuticals (AUPH) 37.3%, Nuvation Bio (NUVB) 79.1%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, AZN, AUPH and NUVB?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Astrazeneca (AZN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.