ARQT vs REGN vs MRNA Stock Comparison

Arcutis Biotherapeutics, Regeneron Pharmaceuticals and Moderna Prices as of Oct 28, 2026 Peers: Industry group
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MRNA Moderna, Inc.
$214.16 +8.6% 1M +744.8% 1Y
Market cap
$86.61B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
2 wins

Head to Head

11 decided of 12

Regeneron Pharmaceuticals leads on 5 of the 12 questions below (Regeneron Pharmaceuticals 5, Arcutis Biotherapeutics 4, Moderna 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionARQTREGNMRNALeader
Larger companyMarket capitalisation $4.15B $83.74B $86.61B MRNA
Cheaper on earningsLower P/E, profitable companies only 145.6x 19.3x -27.5x REGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 62.9x 14.2x — REGN
Faster revenue growthRevenue growth, trailing twelve months +76.1% +9.3% -27.6% ARQT
More profitableNet margin, trailing twelve months 6.1% 27.9% -141.4% REGN
Better return on capitalReturn on invested capital 10.6% 9.6% -43.3% ARQT
Less leveragedLower net debt / EBITDA — -1.4x 1.5x REGN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +26.1% +24.3% +744.8% MRNA
Better 5-year returnAnnualised price return, 5 years +8.2%/yr +4.9%/yr -9.1%/yr ARQT
Less volatileAnnualised volatility, 1 year 51.3% 30.9% 130.6% REGN
Higher overall scoreMean of the five percentile scores vs peers 76/100 72/100 57/100 ARQT

Percentile Scorecard

ARQTREGNMRNA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisARQTREGNMRNA
Valuation 70 #188 of 625 89 #70 of 625 69 #192 of 625
Growth 96 #28 of 602 42 #352 of 602 19 #488 of 602
Profitability 89 #60 of 549 90 #54 of 549 57 #235 of 549
Financial Health 47 #347 of 654 74 #173 of 654 55 #298 of 654
Shareholder Returns 77 #87 of 367 65 #129 of 367 85 #57 of 367
Overall 76 72 57
  • ARQT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • REGN ranked among 672 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodARQTREGNMRNASPY
1 month +15.1%+8.1%+8.6% +0.9%
3 months +12.9%+16.9%+293.0% +5.9%
6 months +40.6%+18.5%+368.4% +8.5%
Year to date +8.3%+5.4%+626.2% +13.3%
1 year +26.1%+24.3%+744.8% +12.4%
3 years +1,246.9%+4.9%+197.8% +88.1%
3 years, per year +138.1%+1.6%+43.9% +23.5%
5 years +48.5%+27.1%-38.0% +68.2%
5 years, per year +8.2%+4.9%-9.1% +11.0%
10 years —+128.6%— +263.4%
10 years, per year —+8.6%— +13.8%

Risk

MeasureARQTREGNMRNASPY
Volatility, 1Y 51.3%30.9%130.6% 12.7%
Downside volatility, 1Y 49.1%29.9%79.5% 12.7%
Beta vs S&P 500, 1Y 1.050.452.16 1.00
Return / volatility, 1Y 0.510.795.70 0.98
Max drawdown, 5Y -93.2%-59.8%-93.9% -25.4%
From 52-week high -4.2%-4.5%-12.9% -0.9%
52-week high $32.82$852.03$245.81 $779.14
52-week low $19.50$600.66$22.36 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleARQTREGNMRNA
P/E now vs peer median 143.9xmedian 17.4x 19.3xmedian 17.4x -27.1xmedian 17.4x
P/S now vs peer median 8.5xmedian 9.1x 5.4xmedian 9.1x 38.4xmedian 9.1x
EV/EBITDA now vs peer median —median 17.1x 17.7xmedian 17.1x -26.3xmedian 17.1x
P/FCF now vs peer median 100.9xmedian 19.0x 22.2xmedian 19.0x -68.7xmedian 19.0x
P/B now vs peer median 17.9xmedian 2.2x 2.6xmedian 2.2x 12.6xmedian 2.2x
PEG now vs peer median 5.37median 0.34 7.26median 0.34 0.42median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsARQTREGNMRNA
Revenue $463.98M $15.53B $2.23B
Gross profit $422.89M $13.18B $521.00M
Operating income $34.25M $3.84B -$3.32B
Net income $28.52M $4.33B -$3.15B
Free cash flow $39.15M $3.76B -$1.24B
R&D $91.04M $6.28B $2.88B
EPS (diluted) $0.21 $40.84 $-7.92
Cash & equivalents – $2.46B $1.72B
Total debt $108.90M $1.99B $591.00M
Shares (diluted) 135.90M 106.00M 398.00M
Enterprise value $3.44B $49.94B $65.96B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricARQTREGNMRNA
P/E 143.9x 19.3x -27.1x
P/FCF 100.9x 22.2x -68.7x
P/Operating cash flow 100.5x 17.9x -79.6x
P/S 8.5x 5.4x 38.4x
P/B 17.9x 2.6x 12.6x
P/Tangible book 19.1x 2.7x 12.6x
EV/EBITDA – 17.7x -26.3x
EV/EBIT 112.5x 20.2x -24.4x
EV/Revenue 8.3x 5.0x 36.3x
EV/FCF 98.4x 20.6x -65.0x
EV/Operating cash flow 98.1x 16.6x -75.4x
PEG (3Y EPS CAGR) 5.37 7.26 0.42

Growth

14 metrics
MetricARQTREGNMRNA
Revenue growth (1Y) 76.1% 9.3% -27.6%
Revenue CAGR (3Y) 241.4% 7.0% -40.6%
Gross profit growth (1Y) 80.2% 8.4% -67.8%
Gross profit CAGR (3Y) 256.4% 6.4% -56.0%
Operating income growth (1Y) 139.9% 0.1% -1.4%
Operating income CAGR (3Y) 28.2% -3.9% -103.9%
Net income growth (1Y) 130.6% -2.9% -8.5%
Net income CAGR (3Y) 27.8% 0.2% -66.4%
EPS growth (1Y) 128.6% -0.5% -5.8%
EPS CAGR (3Y) 26.8% 2.7% -65.1%
Operating cash flow growth (1Y) 160.0% -1.3% 60.2%
Operating cash flow CAGR (3Y) 28.8% -0.4% -68.1%
Free cash flow growth (1Y) 159.0% -2.4% 64.4%
Free cash flow CAGR (3Y) 28.8% -3.3% -18.2%

Profitability

14 metrics
MetricARQTREGNMRNA
Gross margin 91.1% 84.9% 23.4%
EBITDA margin – 28.1% -138.2%
Operating margin 7.4% 24.7% -149.0%
Pretax margin 6.3% 33.3% -138.6%
Net margin 6.1% 27.9% -141.4%
FCF margin 8.4% 24.2% -55.8%
Operating cash flow margin 8.5% 30.1% -48.2%
Return on equity 13.9% 13.7% -44.5%
Return on assets 6.0% 10.5% -28.1%
Return on invested capital 10.6% 9.6% -43.3%
Return on capital employed 10.9% 10.7% -38.2%
Asset turnover 1.0x 0.4x 0.2x
Cash conversion (OCF / net income) 1.4x 1.1x 0.3x
Stock comp / revenue 9.4% 6.4% 20.7%

Financial Health

11 metrics
MetricARQTREGNMRNA
Debt / assets 22.3% 4.8% 5.4%
Debt / equity 0.5x 0.1x 0.1x
Net debt / EBITDA – -1.4x 1.5x
Debt / FCF 2.8x 0.5x -0.5x
Liabilities / assets 54.8% 24.0% 38.3%
Equity / assets 45.2% 76.0% 61.7%
Interest coverage 2.5x 69.4x –
Current ratio 2.9x 3.3x 2.3x
Quick ratio 2.2x 2.6x 2.0x
Cash ratio 1.3x 1.4x 2.0x
Altman Z-score 7.53 7.32 12.42

Shareholder Returns

7 metrics
MetricARQTREGNMRNA
Dividend yield – 0.5% –
Net buyback yield -0.2% 3.0% -0.1%
Shareholder yield -0.2% 3.5% -0.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusARQTREGNMRNA
Forward P/E 62.9xFY2026 14.2xFY2026 –
EPS, next fiscal year $0.50FY2026 $57.08FY2026 $-8.02FY2026
EPS growth, next FY – +28.8%FY2026 –
EPS growth, the year after +152.0% +15.5% –
Revenue, next fiscal year $565.04MFY2026 $17.05BFY2026 $2.04BFY2026
Revenue growth, next FY +50.2%FY2026 +18.9%FY2026 +5.1%FY2026
Revenue growth, the year after +17.0% +13.0% +26.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersARQTREGNMRNA
Held by institutions 100.0% 66.2% 80.2%
Institutions holding 271 1,325 784
Change in shares held, QoQ -0.4% +3.8% +3.4%
Institutions buying 138 604 402
Institutions selling 98 534 238
Buyers to sellers 1.41 1.13 1.69

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ARQTREGNMRNA
ARQT 1.00 0.27 0.18
REGN 0.27 1.00 0.26
MRNA 0.18 0.26 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ARQT, REGN and MRNA?

Moderna (MRNA) is the largest by market capitalisation: Arcutis Biotherapeutics (ARQT) $4.15B, Regeneron Pharmaceuticals (REGN) $83.74B, Moderna (MRNA) $86.61B.

Which stock is cheaper, ARQT, REGN and MRNA?

Regeneron Pharmaceuticals (REGN) trades on the lowest price-to-earnings ratio (Arcutis Biotherapeutics (ARQT) 145.6x, Regeneron Pharmaceuticals (REGN) 19.3x, Moderna (MRNA) -27.5x). On next year's consensus earnings, Regeneron Pharmaceuticals (REGN) is cheapest (Arcutis Biotherapeutics (ARQT) 62.9x, Regeneron Pharmaceuticals (REGN) 14.2x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Arcutis Biotherapeutics (ARQT) grew revenue fastest over the trailing twelve months: Arcutis Biotherapeutics (ARQT) +76.1%, Regeneron Pharmaceuticals (REGN) +9.3%, Moderna (MRNA) -27.6%.

Which company is more profitable?

Regeneron Pharmaceuticals (REGN) has the highest net margin (Arcutis Biotherapeutics (ARQT) 6.1%, Regeneron Pharmaceuticals (REGN) 27.9%, Moderna (MRNA) -141.4%). On return on invested capital, Arcutis Biotherapeutics (ARQT) leads (Arcutis Biotherapeutics (ARQT) 10.6%, Regeneron Pharmaceuticals (REGN) 9.6%, Moderna (MRNA) -43.3%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: Arcutis Biotherapeutics (ARQT) +26.1%, Regeneron Pharmaceuticals (REGN) +24.3%, Moderna (MRNA) +744.8%. Over five years, Arcutis Biotherapeutics (ARQT) compounded fastest (Arcutis Biotherapeutics (ARQT) +8.2%/yr, Regeneron Pharmaceuticals (REGN) +4.9%/yr, Moderna (MRNA) -9.1%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Regeneron Pharmaceuticals (REGN) has been the steadiest (Arcutis Biotherapeutics (ARQT) 51.3%, Regeneron Pharmaceuticals (REGN) 30.9%, Moderna (MRNA) 130.6%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ARQT, REGN and MRNA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Regeneron Pharmaceuticals (REGN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.