ARGX vs AMGN vs REGN Stock Comparison

Argenx Se, Amgen and Regeneron Pharmaceuticals Prices as of Nov 4, 2026 Peers: Industry group
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ARGX Argenx Se
$931.38 +2.0% 1M +12.0% 1Y
Market cap
$57.64B
P/E
30.4x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
4 wins
AMGN Amgen Inc
$478.48 +18.7% 1M +61.3% 1Y
Market cap
$258.67B
P/E
29.6x
Revenue (TTM)
$38.10B
Div. yield
2.08%
Biotechnology Healthcare
5 wins

Head to Head

12 decided of 12

Amgen leads on 5 of the 12 questions below (Amgen 5, Argenx Se 4, Regeneron Pharmaceuticals 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionARGXAMGNREGNLeader
Larger companyMarket capitalisation $57.64B $258.67B $94.65B AMGN
Cheaper on earningsLower P/E, profitable companies only 30.4x 29.6x 19.6x REGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 30.4x 21.9x 16.3x REGN
Faster revenue growthRevenue growth, trailing twelve months +61.5% +9.1% +18.6% ARGX
More profitableNet margin, trailing twelve months 32.3% 23.0% 28.5% ARGX
Better return on capitalReturn on invested capital — 14.3% 11.9% AMGN
Less leveragedLower net debt / EBITDA — 2.7x -1.4x REGN
Higher dividend yieldTrailing dividend yield — 2.08% 0.40% AMGN
Better 1-year returnPrice return, last 12 months +12.0% +61.3% +48.2% AMGN
Better 5-year returnAnnualised price return, 5 years +23.8%/yr +17.5%/yr +8.8%/yr ARGX
Less volatileAnnualised volatility, 1 year 37.2% 29.9% 33.7% AMGN
Higher overall scoreMean of the five percentile scores vs peers 92/100 66/100 74/100 ARGX

Percentile Scorecard

ARGXAMGNREGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisARGXAMGNREGN
Valuation 83 #109 of 634 85 #99 of 634 90 #67 of 634
Growth 95 #34 of 607 61 #238 of 607 52 #292 of 607
Profitability 98 #12 of 557 95 #31 of 557 91 #50 of 557
Financial Health – 22 #511 of 654 74 #170 of 654
Shareholder Returns – 66 #136 of 400 63 #147 of 400
Overall 92 66 74
  • ARGX ranked among 671 companies in Pharmaceuticals and Biotechnology
  • AMGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • REGN ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodARGXAMGNREGNSPY
1 month +2.0%+18.7%+28.0% -1.0%
3 months +7.3%+17.3%+21.1% -0.4%
6 months +15.3%+44.5%+29.1% +4.5%
Year to date +10.8%+46.2%+20.6% +12.4%
1 year +12.0%+61.3%+48.2% +13.6%
3 years +86.3%+77.3%+13.9% +76.4%
3 years, per year +23.1%+21.1%+4.4% +20.8%
5 years +190.2%+123.8%+52.2% +63.7%
5 years, per year +23.8%+17.5%+8.8% +10.4%
10 years —+253.4%+172.6% +267.7%
10 years, per year —+13.5%+10.6% +13.9%

Risk

MeasureARGXAMGNREGNSPY
Volatility, 1Y 37.2%29.9%33.7% 12.8%
Downside volatility, 1Y 34.8%27.9%30.7% 12.7%
Beta vs S&P 500, 1Y 0.430.460.23 1.00
Return / volatility, 1Y 0.322.051.43 1.06
Max drawdown, 5Y -38.2%-26.7%-59.8% -25.4%
From 52-week high -12.0%0.0%-4.4% -1.6%
52-week high $1,058.90$478.48$973.36 $779.14
52-week low $663.93$296.70$600.66 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleARGXAMGNREGN
P/E now vs peer median 30.4xmedian 18.0x 29.6xmedian 18.0x 19.6xmedian 18.0x
P/S now vs peer median 9.9xmedian 9.1x 6.8xmedian 9.1x 5.6xmedian 9.1x
EV/EBITDA now vs peer median —median 16.2x 18.8xmedian 16.2x 16.2xmedian 16.2x
P/FCF now vs peer median —median 21.7x 25.4xmedian 21.7x 24.7xmedian 21.7x
P/B now vs peer median —median 2.2x 22.1xmedian 2.2x 2.8xmedian 2.2x
PEG now vs peer median 0.29median 0.38 11.15median 0.38 2.18median 0.38

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsARGXAMGNREGN
Revenue $5.82B $38.10B $16.90B
Gross profit $5.24B $26.48B $14.49B
Operating income $1.74B $11.43B $4.86B
Net income $1.88B $8.74B $4.82B
Free cash flow – $10.18B $3.83B
R&D $1.80B $7.63B $6.60B
EPS (diluted) $28.43 $16.07 $45.62
Cash & equivalents – $13.99B $3.66B
Total debt – $57.30B $1.99B
Shares (diluted) 66.03M 544.00M 105.60M
Enterprise value $57.64B $214.07B $59.99B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricARGXAMGNREGN
P/E 30.4x 29.6x 19.6x
P/FCF – 25.4x 24.7x
P/Operating cash flow – 20.7x 19.5x
P/S 9.9x 6.8x 5.6x
P/B – 22.1x 2.8x
P/Tangible book – -29.4x 2.9x
EV/EBITDA – 18.8x 16.2x
EV/EBIT 33.1x 26.4x 18.0x
EV/Revenue 9.9x 7.9x 5.2x
EV/FCF – 29.7x 22.8x
EV/Operating cash flow – 24.2x 18.0x
PEG (3Y EPS CAGR) 0.29 11.15 2.18

Growth

14 metrics
MetricARGXAMGNREGN
Revenue growth (1Y) 61.5% 9.1% 18.6%
Revenue CAGR (3Y) 80.5% 12.7% 8.9%
Gross profit growth (1Y) 62.2% 17.6% 19.1%
Gross profit CAGR (3Y) 80.0% 10.3% 8.8%
Operating income growth (1Y) 120.6% 39.5% 31.9%
Operating income CAGR (3Y) 85.1% 6.4% 4.8%
Net income growth (1Y) 22.5% 32.1% 5.2%
Net income CAGR (3Y) 115.5% 3.1% 6.5%
EPS growth (1Y) 20.9% 31.4% 6.8%
EPS CAGR (3Y) 104.8% 2.7% 9.0%
Operating cash flow growth (1Y) – 3.9% -4.4%
Operating cash flow CAGR (3Y) – 4.9% -2.5%
Free cash flow growth (1Y) – -4.1% -9.4%
Free cash flow CAGR (3Y) – 1.7% -6.0%

Profitability

14 metrics
MetricARGXAMGNREGN
Gross margin 90.0% 69.5% 85.8%
EBITDA margin – 42.2% 31.8%
Operating margin 29.9% 30.0% 28.8%
Pretax margin 32.6% 27.0% 33.7%
Net margin 32.3% 23.0% 28.5%
FCF margin – 26.7% 22.6%
Operating cash flow margin – 32.8% 28.7%
Return on equity – 83.8% 14.8%
Return on assets – 9.3% 11.2%
Return on invested capital – 14.3% 11.9%
Return on capital employed – 16.7% 13.2%
Asset turnover – 0.4x 0.4x
Cash conversion (OCF / net income) – 1.4x 1.0x
Stock comp / revenue – 1.3% 6.0%

Financial Health

11 metrics
MetricARGXAMGNREGN
Debt / assets – 59.9% 4.5%
Debt / equity – 4.9x 0.1x
Net debt / EBITDA – 2.7x -1.4x
Debt / FCF – 5.6x 0.5x
Liabilities / assets – 87.8% 24.6%
Equity / assets – 12.2% 75.4%
Interest coverage 10,120x 4.3x 104.2x
Current ratio – 1.4x 3.4x
Quick ratio – 0.9x 2.7x
Cash ratio – 0.5x 1.5x
Altman Z-score – 2.43 7.59

Shareholder Returns

7 metrics
MetricARGXAMGNREGN
Dividend yield – 2.1% 0.4%
Net buyback yield – – 2.1%
Shareholder yield – 2.1% 2.5%
Payout ratio (earnings) – 60.4% –
Payout ratio (FCF) – 51.9% –
Dividend growth (1Y) – 6.3% –
Dividend CAGR (3Y) – 6.7% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusARGXAMGNREGN
Forward P/E 30.4xFY2026 21.9xFY2026 16.3xFY2026
EPS, next fiscal year $30.63FY2026 $21.81FY2026 $57.08FY2026
EPS growth, next FY +56.5%FY2026 -0.1%FY2026 +28.8%FY2026
EPS growth, the year after +26.9% +7.2% +15.5%
Revenue, next fiscal year $6.08BFY2026 $41.51BFY2026 $17.05BFY2026
Revenue growth, next FY +43.1%FY2026 +12.9%FY2026 +18.9%FY2026
Revenue growth, the year after +22.9% +2.3% +13.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersARGXAMGNREGN
Held by institutions 46.1% 82.7% 66.2%
Institutions holding 506 3,163 1,329
Change in shares held, QoQ -2.0% +4.5% +3.8%
Institutions buying 264 1,452 607
Institutions selling 162 1,219 534
Buyers to sellers 1.63 1.19 1.14

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ARGXAMGNREGN
ARGX 1.00 0.33 0.19
AMGN 0.33 1.00 0.46
REGN 0.19 0.46 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ARGX, AMGN and REGN?

Amgen (AMGN) is the largest by market capitalisation: Argenx Se (ARGX) $57.64B, Amgen (AMGN) $258.67B, Regeneron Pharmaceuticals (REGN) $94.65B.

Which stock is cheaper, ARGX, AMGN and REGN?

Regeneron Pharmaceuticals (REGN) trades on the lowest price-to-earnings ratio (Argenx Se (ARGX) 30.4x, Amgen (AMGN) 29.6x, Regeneron Pharmaceuticals (REGN) 19.6x). On next year's consensus earnings, Regeneron Pharmaceuticals (REGN) is cheapest (Argenx Se (ARGX) 30.4x, Amgen (AMGN) 21.9x, Regeneron Pharmaceuticals (REGN) 16.3x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Argenx Se (ARGX) +61.5%, Amgen (AMGN) +9.1%, Regeneron Pharmaceuticals (REGN) +18.6%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Argenx Se (ARGX) 32.3%, Amgen (AMGN) 23.0%, Regeneron Pharmaceuticals (REGN) 28.5%). On return on invested capital, Amgen (AMGN) leads (Amgen (AMGN) 14.3%, Regeneron Pharmaceuticals (REGN) 11.9%).

Which stock has performed better?

Over the past year Amgen (AMGN) returned the most: Argenx Se (ARGX) +12.0%, Amgen (AMGN) +61.3%, Regeneron Pharmaceuticals (REGN) +48.2%. Over five years, Argenx Se (ARGX) compounded fastest (Argenx Se (ARGX) +23.8%/yr, Amgen (AMGN) +17.5%/yr, Regeneron Pharmaceuticals (REGN) +8.8%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Amgen (AMGN) has the highest dividend yield: Amgen (AMGN) 2.08%, Regeneron Pharmaceuticals (REGN) 0.40%. Argenx Se (ARGX) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Amgen (AMGN) has been the steadiest (Argenx Se (ARGX) 37.2%, Amgen (AMGN) 29.9%, Regeneron Pharmaceuticals (REGN) 33.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ARGX, AMGN and REGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amgen (AMGN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.