ARGX vs AMGN vs GILD Stock Comparison

Argenx Se, Amgen and Gilead Sciences Prices as of Nov 3, 2026 Peers: Industry group
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ARGX Argenx Se
$901.12 -2.0% 1M +9.1% 1Y
Market cap
$56.85B
P/E
30.3x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
4 wins
AMGN Amgen Inc
$461.26 +14.4% 1M +55.7% 1Y
Market cap
$257.73B
P/E
29.5x
Revenue (TTM)
$38.10B
Div. yield
0.02%
Biotechnology Healthcare
6 wins
GILD Gilead Sciences, Inc.
$167.47 +15.7% 1M +37.2% 1Y
Market cap
$217.04B
P/E
–
Revenue (TTM)
$30.99B
Div. yield
–
Biotechnology Healthcare
1 win

Head to Head

11 decided of 12

Amgen leads on 6 of the 12 questions below (Amgen 6, Argenx Se 4, Gilead Sciences 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionARGXAMGNGILDLeader
Larger companyMarket capitalisation $56.85B $257.73B $217.04B AMGN
Cheaper on earningsLower P/E, profitable companies only 30.3x 29.5x -56.2x AMGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 29.4x 21.1x — AMGN
Faster revenue growthRevenue growth, trailing twelve months +61.5% +9.1% +6.5% ARGX
More profitableNet margin, trailing twelve months 32.3% 23.0% -12.5% ARGX
Better return on capitalReturn on invested capital — 14.3% -6.1% AMGN
Less leveragedLower net debt / EBITDA — 2.7x 43.8x AMGN
Higher dividend yieldTrailing dividend yield 0.00% 0.02% 0.00% –
Better 1-year returnPrice return, last 12 months +9.1% +55.7% +37.2% AMGN
Better 5-year returnAnnualised price return, 5 years +22.2%/yr +16.5%/yr +20.3%/yr ARGX
Less volatileAnnualised volatility, 1 year 37.1% 29.7% 27.3% GILD
Higher overall scoreMean of the five percentile scores vs peers 92/100 66/100 61/100 ARGX

Percentile Scorecard

ARGXAMGNGILD

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisARGXAMGNGILD
Valuation 83 #106 of 634 85 #99 of 634 90 #64 of 634
Growth 95 #33 of 607 61 #237 of 607 34 #399 of 607
Profitability 98 #12 of 557 95 #30 of 557 84 #90 of 557
Financial Health – 22 #510 of 654 23 #502 of 654
Shareholder Returns – 66 #136 of 401 74 #106 of 401
Overall 92 66 61
  • ARGX ranked among 671 companies in Pharmaceuticals and Biotechnology
  • AMGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • GILD ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodARGXAMGNGILDSPY
1 month -2.0%+14.4%+15.7% -2.0%
3 months +6.7%+18.3%+23.8% -2.2%
6 months +13.4%+39.9%+25.5% +4.2%
Year to date +7.2%+40.9%+36.4% +10.6%
1 year +9.1%+55.7%+37.2% +10.4%
3 years +80.2%+70.9%+105.3% +73.6%
3 years, per year +21.7%+19.6%+27.1% +20.2%
5 years +172.5%+114.6%+151.9% +61.6%
5 years, per year +22.2%+16.5%+20.3% +10.1%
10 years —+241.1%+133.4% +261.3%
10 years, per year —+13.1%+8.8% +13.7%

Risk

MeasureARGXAMGNGILDSPY
Volatility, 1Y 37.1%29.7%27.3% 12.8%
Downside volatility, 1Y 34.8%27.9%23.9% 12.8%
Beta vs S&P 500, 1Y 0.400.430.24 1.00
Return / volatility, 1Y 0.241.881.36 0.81
Max drawdown, 5Y -38.2%-26.7%-29.4% -25.4%
From 52-week high -14.9%-1.0%-2.5% -3.2%
52-week high $1,058.90$466.01$171.68 $779.14
52-week low $663.93$296.30$118.15 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleARGXAMGNGILD
P/E now vs peer median 29.4xmedian 18.4x 28.5xmedian 18.4x -53.8xmedian 18.4x
P/S now vs peer median 9.6xmedian 9.0x 6.5xmedian 9.0x 6.7xmedian 9.0x
EV/EBITDA now vs peer median —median 16.0x 18.2xmedian 16.0x 503.6xmedian 16.0x
P/FCF now vs peer median —median 21.8x 24.5xmedian 21.8x 15.1xmedian 21.8x
P/B now vs peer median —median 2.1x 21.3xmedian 2.1x 15.9xmedian 2.1x
PEG now vs peer median 0.28median 0.37 10.75median 0.37 1.40median 0.37

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsARGXAMGNGILD
Revenue $5.82B $38.10B $30.99B
Gross profit $5.24B $26.48B $24.77B
Operating income $1.74B $11.43B -$2.36B
Net income $1.88B $8.74B -$3.86B
Free cash flow – $10.18B $13.78B
R&D $1.80B $7.63B $6.33B
EPS (diluted) $28.43 $16.07 $-3.09
Cash & equivalents – $13.99B $6.44B
Total debt – $57.30B $26.23B
Shares (diluted) 66.03M 544.00M 1.25B
Enterprise value $56.85B $213.13B $192.15B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricARGXAMGNGILD
P/E 29.4x 28.5x -53.8x
P/FCF – 24.5x 15.1x
P/Operating cash flow – 20.0x 14.4x
P/S 9.6x 6.5x 6.7x
P/B – 21.3x 15.9x
P/Tangible book – -28.3x -541.2x
EV/EBITDA – 18.2x 503.6x
EV/EBIT 32.0x 25.6x -96.4x
EV/Revenue 9.6x 7.7x 7.3x
EV/FCF – 28.8x 16.5x
EV/Operating cash flow – 23.5x 15.7x
PEG (3Y EPS CAGR) 0.28 10.75 1.40

Growth

14 metrics
MetricARGXAMGNGILD
Revenue growth (1Y) 61.5% 9.1% 6.5%
Revenue CAGR (3Y) 80.5% 12.7% 4.2%
Gross profit growth (1Y) 62.2% 17.6% 8.2%
Gross profit CAGR (3Y) 80.0% 10.3% 4.7%
Operating income growth (1Y) 120.6% 39.5% -122.5%
Operating income CAGR (3Y) 85.1% 6.4% -31.7%
Net income growth (1Y) 22.5% 32.1% -147.6%
Net income CAGR (3Y) 115.5% 3.1% -38.5%
EPS growth (1Y) 20.9% 31.4% -147.7%
EPS CAGR (3Y) 104.8% 2.7% -38.6%
Operating cash flow growth (1Y) – 3.9% 49.8%
Operating cash flow CAGR (3Y) – 4.9% 19.9%
Free cash flow growth (1Y) – -4.1% 50.4%
Free cash flow CAGR (3Y) – 1.7% 20.6%

Profitability

14 metrics
MetricARGXAMGNGILD
Gross margin 90.0% 69.5% 79.9%
EBITDA margin – 42.2% 1.5%
Operating margin 29.9% 30.0% -7.6%
Pretax margin 32.6% 27.0% -8.2%
Net margin 32.3% 23.0% -12.5%
FCF margin – 26.7% 44.5%
Operating cash flow margin – 32.8% 46.7%
Return on equity – 83.8% -31.2%
Return on assets – 9.3% -7.7%
Return on invested capital – 14.3% -6.1%
Return on capital employed – 16.7% -6.2%
Asset turnover – 0.4x 0.6x
Cash conversion (OCF / net income) – 1.4x -3.7x
Stock comp / revenue – 1.3% 2.9%

Financial Health

11 metrics
MetricARGXAMGNGILD
Debt / assets – 59.9% 51.0%
Debt / equity – 4.9x 2.0x
Net debt / EBITDA – 2.7x 43.8x
Debt / FCF – 5.6x 1.9x
Liabilities / assets – 87.8% 74.6%
Equity / assets – 12.2% 25.4%
Interest coverage 10,120x 4.3x -2.3x
Current ratio – 1.4x 1.4x
Quick ratio – 0.9x 1.0x
Cash ratio – 0.5x 0.5x
Altman Z-score – 2.37 3.89

Shareholder Returns

7 metrics
MetricARGXAMGNGILD
Dividend yield – 2.2% 1.9%
Net buyback yield – – 0.5%
Shareholder yield – 2.2% 2.5%
Payout ratio (earnings) – 60.4% –
Payout ratio (FCF) – 51.9% –
Dividend growth (1Y) – 6.3% –
Dividend CAGR (3Y) – 6.7% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusARGXAMGNGILD
Forward P/E 29.4xFY2026 21.1xFY2026 –
EPS, next fiscal year $30.63FY2026 $21.81FY2026 $-0.39FY2026
EPS growth, next FY +56.5%FY2026 -0.1%FY2026 -104.8%FY2026
EPS growth, the year after +26.9% +7.2% –
Revenue, next fiscal year $6.08BFY2026 $41.51BFY2026 $28.65BFY2026
Revenue growth, next FY +43.1%FY2026 +12.9%FY2026 -2.7%FY2026
Revenue growth, the year after +22.9% +2.3% +18.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersARGXAMGNGILD
Held by institutions 46.1% 82.7% 89.6%
Institutions holding 506 3,163 2,293
Change in shares held, QoQ -2.0% +4.5% +5.1%
Institutions buying 264 1,452 1,113
Institutions selling 162 1,219 853
Buyers to sellers 1.63 1.19 1.30

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ARGXAMGNGILD
ARGX 1.00 0.32 0.24
AMGN 0.32 1.00 0.54
GILD 0.24 0.54 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ARGX, AMGN and GILD?

Amgen (AMGN) is the largest by market capitalisation: Argenx Se (ARGX) $56.85B, Amgen (AMGN) $257.73B, Gilead Sciences (GILD) $217.04B.

Which stock is cheaper, ARGX, AMGN and GILD?

Amgen (AMGN) trades on the lowest price-to-earnings ratio (Argenx Se (ARGX) 30.3x, Amgen (AMGN) 29.5x, Gilead Sciences (GILD) -56.2x). On next year's consensus earnings, Amgen (AMGN) is cheapest (Argenx Se (ARGX) 29.4x, Amgen (AMGN) 21.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Argenx Se (ARGX) +61.5%, Amgen (AMGN) +9.1%, Gilead Sciences (GILD) +6.5%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Argenx Se (ARGX) 32.3%, Amgen (AMGN) 23.0%, Gilead Sciences (GILD) -12.5%). On return on invested capital, Amgen (AMGN) leads (Amgen (AMGN) 14.3%, Gilead Sciences (GILD) -6.1%).

Which stock has performed better?

Over the past year Amgen (AMGN) returned the most: Argenx Se (ARGX) +9.1%, Amgen (AMGN) +55.7%, Gilead Sciences (GILD) +37.2%. Over five years, Argenx Se (ARGX) compounded fastest (Argenx Se (ARGX) +22.2%/yr, Amgen (AMGN) +16.5%/yr, Gilead Sciences (GILD) +20.3%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Argenx Se (ARGX) 0.00%, Amgen (AMGN) 0.02%, Gilead Sciences (GILD) 0.00%. Argenx Se (ARGX) and Gilead Sciences (GILD) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Gilead Sciences (GILD) has been the steadiest (Argenx Se (ARGX) 37.1%, Amgen (AMGN) 29.7%, Gilead Sciences (GILD) 27.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ARGX, AMGN and GILD?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amgen (AMGN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.