ARGX vs AMGN vs BNTX Stock Comparison

Argenx Se, Amgen and BioNTech SE Prices as of Nov 4, 2026 Peers: Industry group
1 more company in this comparison (MRNA) Create a free account to keep reading and compare up to 10 companies.
ARGX Argenx Se
$931.38 +2.0% 1M +12.0% 1Y
Market cap
$57.64B
P/E
30.4x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
4 wins
AMGN Amgen Inc
$478.48 +18.7% 1M +61.3% 1Y
Market cap
$258.67B
P/E
29.6x
Revenue (TTM)
$38.10B
Div. yield
2.08%
Biotechnology Healthcare
7 wins
BNTX BioNTech SE
$90.70 -7.1% 1M -13.5% 1Y
Market cap
$22.94B
P/E
–
Revenue (TTM)
$2.80B
Div. yield
–
Biotechnology Healthcare

Head to Head

11 decided of 12

Amgen leads on 7 of the 12 questions below (Amgen 7, Argenx Se 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionARGXAMGNBNTXLeader
Larger companyMarket capitalisation $57.64B $258.67B $22.94B AMGN
Cheaper on earningsLower P/E, profitable companies only 30.4x 29.6x -12.7x AMGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 30.4x 21.9x — AMGN
Faster revenue growthRevenue growth, trailing twelve months +61.5% +9.1% -20.8% ARGX
More profitableNet margin, trailing twelve months 32.3% 23.0% -61.4% ARGX
Better return on capitalReturn on invested capital — 14.3% -10.2% AMGN
Less leveragedLower net debt / EBITDA — 2.7x 12.2x AMGN
Higher dividend yieldTrailing dividend yield — 2.08% 0.00% –
Better 1-year returnPrice return, last 12 months +12.0% +61.3% -13.5% AMGN
Better 5-year returnAnnualised price return, 5 years +23.8%/yr +17.5%/yr -16.0%/yr ARGX
Less volatileAnnualised volatility, 1 year 37.2% 29.9% 46.8% AMGN
Higher overall scoreMean of the five percentile scores vs peers 92/100 66/100 62/100 ARGX

Percentile Scorecard

ARGXAMGNBNTX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisARGXAMGNBNTX
Valuation 83 #109 of 634 85 #99 of 634 87 #82 of 634
Growth 95 #34 of 607 61 #238 of 607 10 #546 of 607
Profitability 98 #12 of 557 95 #31 of 557 73 #150 of 557
Financial Health – 22 #511 of 654 88 #81 of 654
Shareholder Returns – 66 #136 of 400 49 #203 of 400
Overall 92 66 62
  • ARGX ranked among 671 companies in Pharmaceuticals and Biotechnology
  • AMGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • BNTX ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodARGXAMGNBNTXSPY
1 month +2.0%+18.7%-7.1% -1.0%
3 months +7.3%+17.3%-1.6% -0.4%
6 months +15.3%+44.5%-4.8% +4.5%
Year to date +10.8%+46.2%-4.7% +12.4%
1 year +12.0%+61.3%-13.5% +13.6%
3 years +86.3%+77.3%-5.3% +76.4%
3 years, per year +23.1%+21.1%-1.8% +20.8%
5 years +190.2%+123.8%-58.1% +63.7%
5 years, per year +23.8%+17.5%-16.0% +10.4%
10 years —+253.4%— +267.7%
10 years, per year —+13.5%— +13.9%

Risk

MeasureARGXAMGNBNTXSPY
Volatility, 1Y 37.2%29.9%46.8% 12.8%
Downside volatility, 1Y 34.8%27.9%46.4% 12.7%
Beta vs S&P 500, 1Y 0.430.461.00 1.00
Return / volatility, 1Y 0.322.05-0.29 1.06
Max drawdown, 5Y -38.2%-26.7%-78.4% -25.4%
From 52-week high -12.0%0.0%-24.0% -1.6%
52-week high $1,058.90$478.48$119.34 $779.14
52-week low $663.93$296.70$83.89 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleARGXAMGNBNTX
P/E now vs peer median 30.4xmedian 18.0x 29.6xmedian 18.0x -12.7xmedian 18.0x
P/S now vs peer median 9.9xmedian 9.1x 6.8xmedian 9.1x 8.2xmedian 9.1x
EV/EBITDA now vs peer median —median 16.2x 18.8xmedian 16.2x -8.7xmedian 16.2x
P/FCF now vs peer median —median 21.7x 25.4xmedian 21.7x -832.6xmedian 21.7x
P/B now vs peer median —median 2.2x 22.1xmedian 2.2x 1.1xmedian 2.2x
PEG now vs peer median 0.29median 0.38 11.15median 0.38 0.34median 0.38

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsARGXAMGNBNTX
Revenue $5.82B $38.10B $2.80B
Gross profit $5.24B $26.48B $2.10B
Operating income $1.74B $11.43B -$2.13B
Net income $1.88B $8.74B -$1.72B
Free cash flow – $10.18B -$27.55M
R&D $1.80B $7.63B $2.74B
EPS (diluted) $28.43 $16.07 $-7.11
Cash & equivalents – $13.99B $11.57B
Total debt – $57.30B $123.50M
Shares (diluted) 66.03M 544.00M 241.70M
Enterprise value $57.64B $214.07B -$36.57B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricARGXAMGNBNTX
P/E 30.4x 29.6x -12.7x
P/FCF – 25.4x -832.6x
P/Operating cash flow – 20.7x -85.0x
P/S 9.9x 6.8x 8.2x
P/B – 22.1x 1.1x
P/Tangible book – -29.4x 1.1x
EV/EBITDA – 18.8x -8.7x
EV/EBIT 33.1x 26.4x -4.5x
EV/Revenue 9.9x 7.9x 3.4x
EV/FCF – 29.7x -346.0x
EV/Operating cash flow – 24.2x -35.3x
PEG (3Y EPS CAGR) 0.29 11.15 0.34

Growth

14 metrics
MetricARGXAMGNBNTX
Revenue growth (1Y) 61.5% 9.1% -20.8%
Revenue CAGR (3Y) 80.5% 12.7% -25.9%
Gross profit growth (1Y) 62.2% 17.6% -28.3%
Gross profit CAGR (3Y) 80.0% 10.3% -30.5%
Operating income growth (1Y) 120.6% 39.5% -107.5%
Operating income CAGR (3Y) 85.1% 6.4% -37.6%
Net income growth (1Y) 22.5% 32.1% -172.4%
Net income CAGR (3Y) 115.5% 3.1% -37.6%
EPS growth (1Y) 20.9% 31.4% -164.3%
EPS CAGR (3Y) 104.8% 2.7% -38.0%
Operating cash flow growth (1Y) – 3.9% -13.4%
Operating cash flow CAGR (3Y) – 4.9% -27.0%
Free cash flow growth (1Y) – -4.1% 35.2%
Free cash flow CAGR (3Y) – 1.7% -26.1%

Profitability

14 metrics
MetricARGXAMGNBNTX
Gross margin 90.0% 69.5% 74.9%
EBITDA margin – 42.2% -39.3%
Operating margin 29.9% 30.0% -76.0%
Pretax margin 32.6% 27.0% -59.7%
Net margin 32.3% 23.0% -61.4%
FCF margin – 26.7% -1.0%
Operating cash flow margin – 32.8% -9.6%
Return on equity – 83.8% -9.4%
Return on assets – 9.3% -8.2%
Return on invested capital – 14.3% -10.2%
Return on capital employed – 16.7% -9.3%
Asset turnover – 0.4x 0.1x
Cash conversion (OCF / net income) – 1.4x 0.2x
Stock comp / revenue – 1.3% 3.6%

Financial Health

11 metrics
MetricARGXAMGNBNTX
Debt / assets – 59.9% 0.5%
Debt / equity – 4.9x 0.0x
Net debt / EBITDA – 2.7x 12.2x
Debt / FCF – 5.6x -4.5x
Liabilities / assets – 87.8% 12.2%
Equity / assets – 12.2% 87.8%
Interest coverage 10,120x 4.3x -57.9x
Current ratio – 1.4x 64.2x
Quick ratio – 0.9x 51.6x
Cash ratio – 0.5x 48.8x
Altman Z-score – 2.43 6.83

Shareholder Returns

7 metrics
MetricARGXAMGNBNTX
Dividend yield – 2.1% –
Net buyback yield – – -3.5%
Shareholder yield – 2.1% -3.5%
Payout ratio (earnings) – 60.4% –
Payout ratio (FCF) – 51.9% –
Dividend growth (1Y) – 6.3% –
Dividend CAGR (3Y) – 6.7% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusARGXAMGNBNTX
Forward P/E 30.4xFY2026 21.9xFY2026 –
EPS, next fiscal year $30.63FY2026 $21.81FY2026 $-6.21FY2026
EPS growth, next FY +56.5%FY2026 -0.1%FY2026 –
EPS growth, the year after +26.9% +7.2% –
Revenue, next fiscal year $6.08BFY2026 $41.51BFY2026 $1.90BFY2026
Revenue growth, next FY +43.1%FY2026 +12.9%FY2026 -43.7%FY2026
Revenue growth, the year after +22.9% +2.3% +11.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersARGXAMGNBNTX
Held by institutions 46.1% 82.7% 19.4%
Institutions holding 506 3,163 283
Change in shares held, QoQ -2.0% +4.5% -1.2%
Institutions buying 264 1,452 136
Institutions selling 162 1,219 73
Buyers to sellers 1.63 1.19 1.86

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ARGXAMGNBNTX
ARGX 1.00 0.33 0.24
AMGN 0.33 1.00 0.36
BNTX 0.24 0.36 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ARGX, AMGN and BNTX?

Amgen (AMGN) is the largest by market capitalisation: Argenx Se (ARGX) $57.64B, Amgen (AMGN) $258.67B, BioNTech SE (BNTX) $22.94B.

Which stock is cheaper, ARGX, AMGN and BNTX?

Amgen (AMGN) trades on the lowest price-to-earnings ratio (Argenx Se (ARGX) 30.4x, Amgen (AMGN) 29.6x, BioNTech SE (BNTX) -12.7x). On next year's consensus earnings, Amgen (AMGN) is cheapest (Argenx Se (ARGX) 30.4x, Amgen (AMGN) 21.9x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Argenx Se (ARGX) +61.5%, Amgen (AMGN) +9.1%, BioNTech SE (BNTX) -20.8%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Argenx Se (ARGX) 32.3%, Amgen (AMGN) 23.0%, BioNTech SE (BNTX) -61.4%). On return on invested capital, Amgen (AMGN) leads (Amgen (AMGN) 14.3%, BioNTech SE (BNTX) -10.2%).

Which stock has performed better?

Over the past year Amgen (AMGN) returned the most: Argenx Se (ARGX) +12.0%, Amgen (AMGN) +61.3%, BioNTech SE (BNTX) -13.5%. Over five years, Argenx Se (ARGX) compounded fastest (Argenx Se (ARGX) +23.8%/yr, Amgen (AMGN) +17.5%/yr, BioNTech SE (BNTX) -16.0%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Amgen (AMGN) 2.08%, BioNTech SE (BNTX) 0.00%. Argenx Se (ARGX) and BioNTech SE (BNTX) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Amgen (AMGN) has been the steadiest (Argenx Se (ARGX) 37.2%, Amgen (AMGN) 29.9%, BioNTech SE (BNTX) 46.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ARGX, AMGN and BNTX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amgen (AMGN) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.