AMGN vs MRNA vs GILD Stock Comparison

Amgen, Moderna and Gilead Sciences Prices as of Oct 23, 2026 Peers: Industry group
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AMGN Amgen Inc
$439.26 +8.2% 1M +50.0% 1Y
Market cap
$240.04B
P/E
27.5x
Revenue (TTM)
$38.10B
Div. yield
0.02%
Biotechnology Healthcare
5 wins
MRNA Moderna, Inc.
$200.10 +9.9% 1M +662.3% 1Y
Market cap
$79.24B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
2 wins
GILD Gilead Sciences, Inc.
$156.04 +3.1% 1M +29.2% 1Y
Market cap
$197.28B
P/E
–
Revenue (TTM)
$30.46B
Div. yield
–
Biotechnology Healthcare
2 wins

Head to Head

9 decided of 12

Amgen leads on 5 of the 12 questions below (Amgen 5, Moderna 2, Gilead Sciences 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAMGNMRNAGILDLeader
Larger companyMarket capitalisation $240.04B $79.24B $197.28B AMGN
Cheaper on earningsLower P/E, profitable companies only 27.5x -25.1x -60.9x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 20.1x — — –
Faster revenue growthRevenue growth, trailing twelve months +9.1% -27.6% +5.5% AMGN
More profitableNet margin, trailing twelve months 23.0% -141.4% -10.6% AMGN
Better return on capitalReturn on invested capital 14.3% -43.3% -6.0% AMGN
Less leveragedLower net debt / EBITDA 2.7x 1.5x 87.7x MRNA
Higher dividend yieldTrailing dividend yield 0.02% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +50.0% +662.3% +29.2% MRNA
Better 5-year returnAnnualised price return, 5 years +16.0%/yr -9.3%/yr +18.4%/yr GILD
Less volatileAnnualised volatility, 1 year 29.6% 130.7% 26.9% GILD
Higher overall scoreMean of the five percentile scores vs peers 66/100 57/100 61/100 AMGN

Percentile Scorecard

AMGNMRNAGILD

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAMGNMRNAGILD
Valuation 85 #92 of 624 69 #196 of 624 90 #62 of 624
Growth 62 #231 of 603 18 #494 of 603 31 #419 of 603
Profitability 94 #32 of 555 57 #242 of 555 85 #84 of 555
Financial Health 22 #512 of 657 55 #299 of 657 21 #518 of 657
Shareholder Returns 68 #118 of 370 85 #58 of 370 77 #86 of 370
Overall 66 57 61
  • AMGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 671 companies in Pharmaceuticals and Biotechnology
  • GILD ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAMGNMRNAGILDSPY
1 month +8.2%+9.9%+3.1% -1.0%
3 months +16.8%+270.1%+20.7% +2.9%
6 months +27.5%+294.4%+19.7% +6.4%
Year to date +34.2%+578.5%+27.1% +11.4%
1 year +50.0%+662.3%+29.2% +13.1%
3 years +59.1%+150.9%+99.7% +79.4%
3 years, per year +16.7%+35.9%+25.9% +21.5%
5 years +109.9%-38.7%+132.1% +67.7%
5 years, per year +16.0%-9.3%+18.4% +10.9%
10 years +177.1%—+110.0% +255.2%
10 years, per year +10.7%—+7.7% +13.5%

Risk

MeasureAMGNMRNAGILDSPY
Volatility, 1Y 29.6%130.7%26.9% 12.7%
Downside volatility, 1Y 27.6%79.5%23.9% 12.7%
Beta vs S&P 500, 1Y 0.442.120.29 1.00
Return / volatility, 1Y 1.695.071.09 1.03
Max drawdown, 5Y -26.7%-93.9%-29.4% -25.4%
From 52-week high -1.8%-18.6%-0.8% -2.5%
52-week high $447.28$245.81$157.37 $779.14
52-week low $291.16$22.36$117.88 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAMGNMRNAGILD
P/E now vs peer median 27.1xmedian 17.2x -25.3xmedian 17.2x -59.9xmedian 17.2x
P/S now vs peer median 6.2xmedian 8.8x 35.8xmedian 8.8x 6.4xmedian 8.8x
EV/EBITDA now vs peer median 17.4xmedian 16.0x -24.5xmedian 16.0x 824.0xmedian 16.0x
P/FCF now vs peer median 23.3xmedian 17.8x -64.2xmedian 17.8x 15.0xmedian 17.8x
P/B now vs peer median 20.3xmedian 2.1x 11.8xmedian 2.1x 16.4xmedian 2.1x
PEG now vs peer median 10.23median 0.32 0.39median 0.32 1.60median 0.32

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAMGNMRNAGILD
Revenue $38.10B $2.23B $30.46B
Gross profit $26.48B $521.00M $24.24B
Operating income $11.43B -$3.32B -$2.50B
Net income $8.74B -$3.15B -$3.24B
Free cash flow $10.18B -$1.24B $12.94B
R&D $7.63B $2.88B $6.07B
EPS (diluted) $16.07 $-7.92 $-2.61
Cash & equivalents $13.99B $1.72B $3.18B
Total debt $57.30B $591.00M $26.25B
Shares (diluted) 544.00M 398.00M 1.24B
Enterprise value $195.44B $58.60B $171.47B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAMGNMRNAGILD
P/E 27.1x -25.3x -59.9x
P/FCF 23.3x -64.2x 15.0x
P/Operating cash flow 19.0x -74.4x 14.3x
P/S 6.2x 35.8x 6.4x
P/B 20.3x 11.8x 16.4x
P/Tangible book -27.0x 11.8x -87.9x
EV/EBITDA 17.4x -24.5x 824.0x
EV/EBIT 24.6x -22.7x -86.8x
EV/Revenue 7.4x 33.8x 7.1x
EV/FCF 27.6x -60.5x 16.7x
EV/Operating cash flow 22.5x -70.2x 16.0x
PEG (3Y EPS CAGR) 10.23 0.39 1.60

Growth

14 metrics
MetricAMGNMRNAGILD
Revenue growth (1Y) 9.1% -27.6% 5.5%
Revenue CAGR (3Y) 12.7% -40.6% 3.6%
Gross profit growth (1Y) 17.6% -67.8% 6.9%
Gross profit CAGR (3Y) 10.3% -56.0% 3.7%
Operating income growth (1Y) 39.5% -1.4% -131.0%
Operating income CAGR (3Y) 6.4% -103.9% -31.9%
Net income growth (1Y) 32.1% -8.5% -151.3%
Net income CAGR (3Y) 3.1% -66.4% -37.3%
EPS growth (1Y) 31.4% -5.8% -151.8%
EPS CAGR (3Y) 2.7% -65.1% -37.5%
Operating cash flow growth (1Y) 3.9% 60.2% 37.3%
Operating cash flow CAGR (3Y) 4.9% -68.1% 12.5%
Free cash flow growth (1Y) -4.1% 64.4% 38.1%
Free cash flow CAGR (3Y) 1.7% -18.2% 13.2%

Profitability

14 metrics
MetricAMGNMRNAGILD
Gross margin 69.5% 23.4% 79.6%
EBITDA margin 42.2% -138.2% 0.9%
Operating margin 30.0% -149.0% -8.2%
Pretax margin 27.0% -138.6% -6.4%
Net margin 23.0% -141.4% -10.6%
FCF margin 26.7% -55.8% 42.5%
Operating cash flow margin 32.8% -48.2% 44.5%
Return on equity 83.8% -44.5% -18.4%
Return on assets 9.3% -28.1% -6.1%
Return on invested capital 14.3% -43.3% -6.0%
Return on capital employed 16.7% -38.2% -6.0%
Asset turnover 0.4x 0.2x 0.6x
Cash conversion (OCF / net income) 1.4x 0.3x -4.2x
Stock comp / revenue 1.3% 20.7% 3.0%

Financial Health

11 metrics
MetricAMGNMRNAGILD
Debt / assets 59.9% 5.4% 53.2%
Debt / equity 4.9x 0.1x 2.2x
Net debt / EBITDA 2.7x 1.5x 87.7x
Debt / FCF 5.6x -0.5x 2.0x
Liabilities / assets 87.8% 38.3% 76.0%
Equity / assets 12.2% 61.7% 24.0%
Interest coverage 4.3x – -2.5x
Current ratio 1.4x 2.3x 1.3x
Quick ratio 0.9x 2.0x 0.7x
Cash ratio 0.5x 2.0x 0.3x
Altman Z-score 2.28 11.62 3.68

Shareholder Returns

7 metrics
MetricAMGNMRNAGILD
Dividend yield 2.3% – 2.1%
Net buyback yield – -0.1% 0.6%
Shareholder yield 2.3% -0.1% 2.7%
Payout ratio (earnings) 60.4% – –
Payout ratio (FCF) 51.9% – –
Dividend growth (1Y) 6.3% – –
Dividend CAGR (3Y) 6.7% – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAMGNMRNAGILD
Forward P/E 20.1xFY2026 – –
EPS, next fiscal year $21.80FY2026 $-7.92FY2026 $-0.39FY2026
EPS growth, next FY -0.2%FY2026 – -104.8%FY2026
EPS growth, the year after +7.3% – –
Revenue, next fiscal year $41.51BFY2026 $2.04BFY2026 $28.60BFY2026
Revenue growth, next FY +12.9%FY2026 +5.1%FY2026 -2.9%FY2026
Revenue growth, the year after +2.2% +26.8% +18.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAMGNMRNAGILD
Held by institutions 82.7% 80.2% 89.6%
Institutions holding 3,159 784 2,290
Change in shares held, QoQ +4.5% +3.4% +5.1%
Institutions buying 1,451 402 1,113
Institutions selling 1,217 238 850
Buyers to sellers 1.19 1.69 1.31

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AMGNMRNAGILD
AMGN 1.00 0.25 0.51
MRNA 0.25 1.00 0.24
GILD 0.51 0.24 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, AMGN, MRNA and GILD?

Amgen (AMGN) is the largest by market capitalisation: Amgen (AMGN) $240.04B, Moderna (MRNA) $79.24B, Gilead Sciences (GILD) $197.28B.

Which company is growing faster?

Amgen (AMGN) grew revenue fastest over the trailing twelve months: Amgen (AMGN) +9.1%, Moderna (MRNA) -27.6%, Gilead Sciences (GILD) +5.5%.

Which company is more profitable?

Amgen (AMGN) has the highest net margin (Amgen (AMGN) 23.0%, Moderna (MRNA) -141.4%, Gilead Sciences (GILD) -10.6%). On return on invested capital, Amgen (AMGN) leads (Amgen (AMGN) 14.3%, Moderna (MRNA) -43.3%, Gilead Sciences (GILD) -6.0%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: Amgen (AMGN) +50.0%, Moderna (MRNA) +662.3%, Gilead Sciences (GILD) +29.2%. Over five years, Gilead Sciences (GILD) compounded fastest (Amgen (AMGN) +16.0%/yr, Moderna (MRNA) -9.3%/yr, Gilead Sciences (GILD) +18.4%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Amgen (AMGN) 0.02%, Moderna (MRNA) 0.00%, Gilead Sciences (GILD) 0.00%. Moderna (MRNA) and Gilead Sciences (GILD) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Gilead Sciences (GILD) has been the steadiest (Amgen (AMGN) 29.6%, Moderna (MRNA) 130.7%, Gilead Sciences (GILD) 26.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, AMGN, MRNA and GILD?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amgen (AMGN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.