AMGN vs BNTX vs ARGX Stock Comparison

Amgen, BioNTech SE and Argenx Se Prices as of Oct 29, 2026 Peers: Industry group
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AMGN Amgen Inc
$460.73 +8.8% 1M +57.9% 1Y
Market cap
$252.29B
P/E
28.9x
Revenue (TTM)
$38.10B
Div. yield
0.02%
Biotechnology Healthcare
7 wins
BNTX BioNTech SE
$89.13 -9.6% 1M -13.8% 1Y
Market cap
$21.24B
P/E
–
Revenue (TTM)
$3.09B
Div. yield
–
Biotechnology Healthcare
ARGX Argenx Se
$897.85 -7.5% 1M +9.2% 1Y
Market cap
$54.91B
P/E
29.3x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
4 wins

Head to Head

11 decided of 12

Amgen leads on 7 of the 12 questions below (Amgen 7, Argenx Se 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAMGNBNTXARGXLeader
Larger companyMarket capitalisation $252.29B $21.24B $54.91B AMGN
Cheaper on earningsLower P/E, profitable companies only 28.9x -10.8x 29.3x AMGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 21.1x — 29.3x AMGN
Faster revenue growthRevenue growth, trailing twelve months +9.1% -1.1% +61.5% ARGX
More profitableNet margin, trailing twelve months 23.0% -63.5% 32.3% ARGX
Better return on capitalReturn on invested capital 14.3% -10.7% — AMGN
Less leveragedLower net debt / EBITDA 2.7x 8.7x — AMGN
Higher dividend yieldTrailing dividend yield 0.02% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +57.9% -13.8% +9.2% AMGN
Better 5-year returnAnnualised price return, 5 years +17.4%/yr -20.4%/yr +24.4%/yr ARGX
Less volatileAnnualised volatility, 1 year 29.7% 46.6% 36.9% AMGN
Higher overall scoreMean of the five percentile scores vs peers 66/100 65/100 92/100 ARGX

Percentile Scorecard

AMGNBNTXARGX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAMGNBNTXARGX
Valuation 85 #95 of 624 90 #61 of 624 83 #108 of 624
Growth 61 #234 of 601 15 #512 of 601 95 #34 of 601
Profitability 94 #31 of 541 77 #123 of 541 98 #11 of 541
Financial Health 21 #509 of 647 89 #72 of 647 –
Shareholder Returns 68 #114 of 359 52 #174 of 359 –
Overall 66 65 92
  • AMGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • BNTX ranked among 671 companies in Pharmaceuticals and Biotechnology
  • ARGX ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAMGNBNTXARGXSPY
1 month +8.8%-9.6%-7.5% +0.7%
3 months +18.9%-4.0%+2.9% +3.7%
6 months +33.1%-13.8%+14.9% +7.1%
Year to date +40.8%-6.4%+6.8% +12.8%
1 year +57.9%-13.8%+9.2% +11.9%
3 years +75.1%-4.4%+93.4% +85.2%
3 years, per year +20.5%-1.5%+24.6% +22.8%
5 years +122.6%-68.0%+197.3% +67.6%
5 years, per year +17.4%-20.4%+24.4% +10.9%
10 years +217.4%—— +262.0%
10 years, per year +12.2%—— +13.7%

Risk

MeasureAMGNBNTXARGXSPY
Volatility, 1Y 29.7%46.6%36.9% 12.7%
Downside volatility, 1Y 28.0%46.8%34.7% 12.6%
Beta vs S&P 500, 1Y 0.450.950.39 1.00
Return / volatility, 1Y 1.95-0.290.25 0.94
Max drawdown, 5Y -26.7%-78.4%-38.2% -25.4%
From 52-week high 0.0%-25.3%-15.2% -1.2%
52-week high $460.73$119.34$1,058.90 $779.14
52-week low $291.77$83.89$663.93 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAMGNBNTXARGX
P/E now vs peer median 28.5xmedian 17.8x -11.0xmedian 17.8x 29.3xmedian 17.8x
P/S now vs peer median 6.5xmedian 9.1x 7.3xmedian 9.1x 9.5xmedian 9.1x
EV/EBITDA now vs peer median 18.2xmedian 15.0x -6.0xmedian 15.0x —median 15.0x
P/FCF now vs peer median 24.5xmedian 21.7x 21.7xmedian 21.7x —median 21.7x
P/B now vs peer median 21.3xmedian 2.2x 1.1xmedian 2.2x —median 2.2x
PEG now vs peer median 10.73median 0.35 0.31median 0.35 0.28median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAMGNBNTXARGX
Revenue $38.10B $3.09B $5.82B
Gross profit $26.48B $2.34B $5.24B
Operating income $11.43B -$2.33B $1.74B
Net income $8.74B -$1.97B $1.88B
Free cash flow $10.18B $1.04B –
R&D $7.63B $2.54B $1.80B
EPS (diluted) $16.07 $-8.13 $28.43
Cash & equivalents $13.99B $11.13B –
Total debt $57.30B $102.80M –
Shares (diluted) 544.00M 241.70M 66.03M
Enterprise value $207.69B -$25.24B $54.91B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAMGNBNTXARGX
P/E 28.5x -11.0x 29.3x
P/FCF 24.5x 21.7x –
P/Operating cash flow 20.0x 28.4x –
P/S 6.5x 7.3x 9.5x
P/B 21.3x 1.1x –
P/Tangible book -28.3x 1.1x –
EV/EBITDA 18.2x -6.0x –
EV/EBIT 25.6x -4.0x 31.9x
EV/Revenue 7.7x 3.0x 9.5x
EV/FCF 28.7x 8.9x –
EV/Operating cash flow 23.4x 11.6x –
PEG (3Y EPS CAGR) 10.73 0.31 0.28

Growth

14 metrics
MetricAMGNBNTXARGX
Revenue growth (1Y) 9.1% -1.1% 61.5%
Revenue CAGR (3Y) 12.7% -31.0% 80.5%
Gross profit growth (1Y) 17.6% -6.4% 62.2%
Gross profit CAGR (3Y) 10.3% -34.2% 80.0%
Operating income growth (1Y) 39.5% -142.6% 120.6%
Operating income CAGR (3Y) 6.4% -33.8% 85.1%
Net income growth (1Y) 32.1% -417.0% 22.5%
Net income CAGR (3Y) 3.1% -34.6% 115.5%
EPS growth (1Y) 31.4% -393.7% 20.9%
EPS CAGR (3Y) 2.7% -34.9% 104.8%
Operating cash flow growth (1Y) 3.9% 142.8% –
Operating cash flow CAGR (3Y) 4.9% -56.6% –
Free cash flow growth (1Y) -4.1% 164.1% –
Free cash flow CAGR (3Y) 1.7% -53.1% –

Profitability

14 metrics
MetricAMGNBNTXARGX
Gross margin 69.5% 75.5% 90.0%
EBITDA margin 42.2% -49.7% –
Operating margin 30.0% -75.2% 29.9%
Pretax margin 27.0% -61.4% 32.6%
Net margin 23.0% -63.5% 32.3%
FCF margin 26.7% 33.6% –
Operating cash flow margin 32.8% 25.6% –
Return on equity 83.8% -10.3% –
Return on assets 9.3% -9.0% –
Return on invested capital 14.3% -10.7% –
Return on capital employed 16.7% -9.9% –
Asset turnover 0.4x 0.1x –
Cash conversion (OCF / net income) 1.4x -0.4x –
Stock comp / revenue 1.3% 3.6% –

Financial Health

11 metrics
MetricAMGNBNTXARGX
Debt / assets 59.9% 0.4% –
Debt / equity 4.9x 0.0x –
Net debt / EBITDA 2.7x 8.7x –
Debt / FCF 5.6x 0.1x –
Liabilities / assets 87.8% 12.7% –
Equity / assets 12.2% 87.3% –
Interest coverage 4.3x -41.1x 10,120x
Current ratio 1.4x 65.1x –
Quick ratio 0.9x 50.7x –
Cash ratio 0.5x 50.0x –
Altman Z-score 2.37 6.41 –

Shareholder Returns

7 metrics
MetricAMGNBNTXARGX
Dividend yield 2.2% – –
Net buyback yield – -2.9% –
Shareholder yield 2.2% -2.9% –
Payout ratio (earnings) 60.4% – –
Payout ratio (FCF) 51.9% – –
Dividend growth (1Y) 6.3% – –
Dividend CAGR (3Y) 6.7% – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAMGNBNTXARGX
Forward P/E 21.1xFY2026 – 29.3xFY2026
EPS, next fiscal year $21.81FY2026 $-6.21FY2026 $30.63FY2026
EPS growth, next FY -0.1%FY2026 – +56.5%FY2026
EPS growth, the year after +7.2% – +26.9%
Revenue, next fiscal year $41.51BFY2026 $1.90BFY2026 $6.08BFY2026
Revenue growth, next FY +12.9%FY2026 -43.7%FY2026 +43.1%FY2026
Revenue growth, the year after +2.3% +11.9% +22.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAMGNBNTXARGX
Held by institutions 82.7% 19.4% 46.1%
Institutions holding 3,161 282 505
Change in shares held, QoQ +4.5% -1.2% -2.0%
Institutions buying 1,452 136 264
Institutions selling 1,218 73 161
Buyers to sellers 1.19 1.86 1.64

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AMGNBNTXARGX
AMGN 1.00 0.34 0.31
BNTX 0.34 1.00 0.23
ARGX 0.31 0.23 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, AMGN, BNTX and ARGX?

Amgen (AMGN) is the largest by market capitalisation: Amgen (AMGN) $252.29B, BioNTech SE (BNTX) $21.24B, Argenx Se (ARGX) $54.91B.

Which stock is cheaper, AMGN, BNTX and ARGX?

Amgen (AMGN) trades on the lowest price-to-earnings ratio (Amgen (AMGN) 28.9x, BioNTech SE (BNTX) -10.8x, Argenx Se (ARGX) 29.3x). On next year's consensus earnings, Amgen (AMGN) is cheapest (Amgen (AMGN) 21.1x, Argenx Se (ARGX) 29.3x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Amgen (AMGN) +9.1%, BioNTech SE (BNTX) -1.1%, Argenx Se (ARGX) +61.5%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Amgen (AMGN) 23.0%, BioNTech SE (BNTX) -63.5%, Argenx Se (ARGX) 32.3%). On return on invested capital, Amgen (AMGN) leads (Amgen (AMGN) 14.3%, BioNTech SE (BNTX) -10.7%).

Which stock has performed better?

Over the past year Amgen (AMGN) returned the most: Amgen (AMGN) +57.9%, BioNTech SE (BNTX) -13.8%, Argenx Se (ARGX) +9.2%. Over five years, Argenx Se (ARGX) compounded fastest (Amgen (AMGN) +17.4%/yr, BioNTech SE (BNTX) -20.4%/yr, Argenx Se (ARGX) +24.4%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Amgen (AMGN) 0.02%, BioNTech SE (BNTX) 0.00%, Argenx Se (ARGX) 0.00%. BioNTech SE (BNTX) and Argenx Se (ARGX) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Amgen (AMGN) has been the steadiest (Amgen (AMGN) 29.7%, BioNTech SE (BNTX) 46.6%, Argenx Se (ARGX) 36.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, AMGN, BNTX and ARGX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amgen (AMGN) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.