ALNY vs MRNA vs ROIV Stock Comparison

Alnylam Pharmaceuticals, Moderna and Roivant Sciences Prices as of Nov 2, 2026 Peers: Industry group
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MRNA Moderna, Inc.
$220.83 +16.2% 1M +713.1% 1Y
Market cap
$98.85B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
2 wins
ROIV Roivant Sciences Ltd.
$35.89 +0.5% 1M +79.5% 1Y
Market cap
$26.24B
P/E
–
Revenue (TTM)
$7.53M
Div. yield
–
Biotechnology Healthcare
2 wins

Head to Head

8 decided of 12

Alnylam Pharmaceuticals leads on 4 of the 12 questions below (Alnylam Pharmaceuticals 4, Moderna 2, Roivant Sciences 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionALNYMRNAROIVLeader
Larger companyMarket capitalisation $21.86B $98.85B $26.24B MRNA
Cheaper on earningsLower P/E, profitable companies only 8.3x -31.4x -98.6x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 23.7x — — –
Faster revenue growthRevenue growth, trailing twelve months +60.8% -27.6% -67.6% ALNY
More profitableNet margin, trailing twelve months 52.8% -141.4% -3,535.0% ALNY
Better return on capitalReturn on invested capital — -43.3% — –
Less leveragedLower net debt / EBITDA -3.1x 1.5x — ALNY
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -65.4% +713.1% +79.5% MRNA
Better 5-year returnAnnualised price return, 5 years -1.8%/yr -8.6%/yr +35.2%/yr ROIV
Less volatileAnnualised volatility, 1 year 58.7% 129.9% 45.1% ROIV
Higher overall scoreMean of the five percentile scores vs peers 82/100 57/100 65/100 ALNY

Percentile Scorecard

ALNYMRNAROIV

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisALNYMRNAROIV
Valuation 91 #55 of 623 69 #194 of 623 63 #231 of 623
Growth 99 #8 of 601 19 #486 of 601 49 #306 of 601
Profitability 90 #56 of 553 57 #238 of 553 30 #387 of 553
Financial Health 62 #249 of 654 54 #300 of 654 93 #45 of 654
Shareholder Returns 69 #114 of 367 86 #54 of 367 90 #37 of 367
Overall 82 57 65
  • ALNY ranked among 671 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 671 companies in Pharmaceuticals and Biotechnology
  • ROIV ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodALNYMRNAROIVSPY
1 month -28.1%+16.2%+0.5% -2.3%
3 months -28.3%+300.5%+7.7% -0.7%
6 months -47.0%+366.9%+26.6% +4.8%
Year to date -60.3%+648.8%+65.4% +10.3%
1 year -65.4%+713.1%+79.5% +10.3%
3 years -5.6%+184.8%+286.7% +73.0%
3 years, per year -1.9%+41.8%+57.0% +20.1%
5 years -8.6%-36.2%+352.0% +61.9%
5 years, per year -1.8%-8.6%+35.2% +10.1%
10 years +339.5%—— +258.6%
10 years, per year +16.0%—— +13.6%

Risk

MeasureALNYMRNAROIVSPY
Volatility, 1Y 58.7%129.9%45.1% 12.8%
Downside volatility, 1Y 74.5%78.6%32.6% 12.8%
Beta vs S&P 500, 1Y 0.442.241.02 1.00
Return / volatility, 1Y -1.115.491.76 0.80
Max drawdown, 5Y -67.8%-93.9%-79.2% -25.4%
From 52-week high -66.6%-10.2%-14.2% -3.5%
52-week high $473.29$245.81$41.81 $779.14
52-week low $158.00$22.36$19.60 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleALNYMRNAROIV
P/E now vs peer median 8.0xmedian 17.4x -27.9xmedian 17.4x -97.2xmedian 17.4x
P/S now vs peer median 4.2xmedian 8.9x 39.5xmedian 8.9x 3,444xmedian 8.9x
EV/EBITDA now vs peer median 17.3xmedian 17.0x -27.1xmedian 17.0x -37.2xmedian 17.0x
P/FCF now vs peer median 26.2xmedian 21.4x -70.8xmedian 21.4x -31.6xmedian 21.4x
P/B now vs peer median 5.9xmedian 2.1x 13.0xmedian 2.1x 5.3xmedian 2.1x
PEG now vs peer median 0.09median 0.35 0.43median 0.35 -2.87median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsALNYMRNAROIV
Revenue $5.01B $2.23B $7.53M
Gross profit $3.88B $521.00M $6.12M
Operating income $977.59M -$3.32B -$596.14M
Net income $2.65B -$3.15B -$414.60M
Free cash flow $806.31M -$1.24B -$821.06M
R&D $1.56B $2.88B $730.91M
EPS (diluted) $19.16 $-7.92 $-0.37
Cash & equivalents $1.75B $1.72B $1.25B
Total debt $361.53M $591.00M –
Shares (diluted) 138.28M 398.00M 720.78M
Enterprise value $9.05B $78.20B $9.19B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricALNYMRNAROIV
P/E 8.0x -27.9x -97.2x
P/FCF 26.2x -70.8x -31.6x
P/Operating cash flow 22.1x -82.1x -31.8x
P/S 4.2x 39.5x 3,444x
P/B 5.9x 13.0x 5.3x
P/Tangible book 5.9x 13.0x 5.3x
EV/EBITDA 17.3x -27.1x -37.2x
EV/EBIT 18.3x -25.2x -37.1x
EV/Revenue 3.6x 37.5x 2,933x
EV/FCF 22.2x -67.2x -26.9x
EV/Operating cash flow 18.7x -77.9x -27.1x
PEG (3Y EPS CAGR) 0.09 0.43 -2.87

Growth

14 metrics
MetricALNYMRNAROIV
Revenue growth (1Y) 60.8% -27.6% -67.6%
Revenue CAGR (3Y) 42.7% -40.6% -46.4%
Gross profit growth (1Y) 49.6% -67.8% -72.7%
Gross profit CAGR (3Y) 37.8% -56.0% -47.9%
Operating income growth (1Y) 269.3% -1.4% 49.7%
Operating income CAGR (3Y) 68.2% -103.9% 12.9%
Net income growth (1Y) 2,137% -8.5% 34.9%
Net income CAGR (3Y) 93.1% -66.4% 26.5%
EPS growth (1Y) 2,122% -5.8% 48.8%
EPS CAGR (3Y) 90.7% -65.1% 33.9%
Operating cash flow growth (1Y) 351.6% 60.2% 4.1%
Operating cash flow CAGR (3Y) 685.4% -68.1% 1.0%
Free cash flow growth (1Y) 382.3% 64.4% 4.4%
Free cash flow CAGR (3Y) 141.7% -18.2% 1.0%

Profitability

14 metrics
MetricALNYMRNAROIV
Gross margin 77.4% 23.4% 81.2%
EBITDA margin 20.6% -138.2% -7,877%
Operating margin 19.5% -149.0% -7,915%
Pretax margin 15.6% -138.6% -3,849%
Net margin 52.8% -141.4% -3,535%
FCF margin 16.1% -55.8% -10,901%
Operating cash flow margin 19.1% -48.2% -10,840%
Return on equity 106.9% -44.5% -8.1%
Return on assets 39.1% -28.1% -7.5%
Return on invested capital – -43.3% –
Return on capital employed 20.7% -38.2% -11.4%
Asset turnover 0.7x 0.2x 0.0x
Cash conversion (OCF / net income) 0.4x 0.3x 2.0x
Stock comp / revenue 6.1% 20.7% 4,611%

Financial Health

11 metrics
MetricALNYMRNAROIV
Debt / assets 4.5% 5.4% –
Debt / equity 0.1x 0.1x –
Net debt / EBITDA -3.1x 1.5x –
Debt / FCF 0.4x -0.5x –
Liabilities / assets 54.9% 38.3% 7.2%
Equity / assets 45.1% 61.7% 92.8%
Interest coverage 3.2x – –
Current ratio 2.5x 2.3x 16.7x
Quick ratio 2.3x 2.0x 13.5x
Cash ratio 1.7x 2.0x 13.5x
Altman Z-score 3.65 12.80 40.86

Shareholder Returns

7 metrics
MetricALNYMRNAROIV
Dividend yield – – –
Net buyback yield -0.5% -0.1% 0.0%
Shareholder yield -0.5% -0.1% 0.0%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusALNYMRNAROIV
Forward P/E 23.7xFY2026 – –
EPS, next fiscal year $6.76FY2026 $-8.02FY2026 $-1.43FY2026
EPS growth, next FY +190.1%FY2026 – –
EPS growth, the year after +34.3% – –
Revenue, next fiscal year $5.68BFY2026 $2.04BFY2026 $55.64MFY2026
Revenue growth, next FY +53.1%FY2026 +5.1%FY2026 +573.6%FY2026
Revenue growth, the year after +27.8% +26.8% +681.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersALNYMRNAROIV
Held by institutions 99.7% 80.2% 77.0%
Institutions holding 788 786 500
Change in shares held, QoQ +3.8% +3.4% +5.1%
Institutions buying 412 403 304
Institutions selling 279 239 138
Buyers to sellers 1.48 1.69 2.20

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ALNYMRNAROIV
ALNY 1.00 0.18 0.02
MRNA 0.18 1.00 0.15
ROIV 0.02 0.15 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, ALNY, MRNA and ROIV?

Moderna (MRNA) is the largest by market capitalisation: Alnylam Pharmaceuticals (ALNY) $21.86B, Moderna (MRNA) $98.85B, Roivant Sciences (ROIV) $26.24B.

Which company is growing faster?

Alnylam Pharmaceuticals (ALNY) grew revenue fastest over the trailing twelve months: Alnylam Pharmaceuticals (ALNY) +60.8%, Moderna (MRNA) -27.6%, Roivant Sciences (ROIV) -67.6%.

Which company is more profitable?

Alnylam Pharmaceuticals (ALNY) has the highest net margin (Alnylam Pharmaceuticals (ALNY) 52.8%, Moderna (MRNA) -141.4%, Roivant Sciences (ROIV) -3,535.0%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: Alnylam Pharmaceuticals (ALNY) -65.4%, Moderna (MRNA) +713.1%, Roivant Sciences (ROIV) +79.5%. Over five years, Roivant Sciences (ROIV) compounded fastest (Alnylam Pharmaceuticals (ALNY) -1.8%/yr, Moderna (MRNA) -8.6%/yr, Roivant Sciences (ROIV) +35.2%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Roivant Sciences (ROIV) has been the steadiest (Alnylam Pharmaceuticals (ALNY) 58.7%, Moderna (MRNA) 129.9%, Roivant Sciences (ROIV) 45.1%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ALNY, MRNA and ROIV?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Alnylam Pharmaceuticals (ALNY) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.