ALLO vs LEGN vs MESO Stock Comparison

Allogene Therapeutics, Legend Biotech and Mesoblast Prices as of Nov 2, 2026 Peers: Industry group
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LEGN Legend Biotech Corp
$21.10 +13.6% 1M -34.9% 1Y
Market cap
$4.09B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
3 wins
MESO Mesoblast Ltd
$14.54 +3.3% 1M -12.7% 1Y
Market cap
$1.84B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
3 wins

Head to Head

6 decided of 12

Legend Biotech leads on 3 of the 12 questions below (Legend Biotech 3, Mesoblast 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionALLOLEGNMESOLeader
Larger companyMarket capitalisation $378.27M $4.09B $1.84B LEGN
Cheaper on earningsLower P/E, profitable companies only -2.3x -44.6x -33.3x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months — +59.5% — –
More profitableNet margin, trailing twelve months -3,566.7% -7.2% — LEGN
Better return on capitalReturn on invested capital — -4.2% — –
Less leveragedLower net debt / EBITDA — -130.2x — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -12.9% -34.9% -12.7% MESO
Better 5-year returnAnnualised price return, 5 years -44.3%/yr -16.4%/yr +3.1%/yr MESO
Less volatileAnnualised volatility, 1 year 83.5% 72.5% 57.3% MESO
Higher overall scoreMean of the five percentile scores vs peers 55/100 74/100 — LEGN

Percentile Scorecard

ALLOLEGNMESO

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisALLOLEGNMESO
Valuation 17 #517 of 623 89 #71 of 623 68 #199 of 623
Growth 91 #58 of 601 97 #20 of 601 –
Profitability 25 #418 of 553 80 #112 of 553 –
Financial Health 63 #244 of 654 60 #263 of 654 44 #366 of 654
Shareholder Returns 79 #79 of 367 44 #207 of 367 –
Overall 55 74 –
  • ALLO ranked among 671 companies in Pharmaceuticals and Biotechnology
  • LEGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • MESO ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodALLOLEGNMESOSPY
1 month -28.0%+13.6%+3.3% -2.3%
3 months -41.3%+11.0%+0.5% -0.7%
6 months -52.2%-20.4%-9.1% +4.8%
Year to date -21.2%-2.9%-19.4% +10.3%
1 year -12.9%-34.9%-12.7% +10.3%
3 years -69.1%-68.0%+463.6% +73.0%
3 years, per year -32.4%-31.6%+78.0% +20.1%
5 years -94.6%-59.2%+16.5% +61.9%
5 years, per year -44.3%-16.4%+3.1% +10.1%
10 years ——+68.3% +258.6%
10 years, per year ——+5.3% +13.6%

Risk

MeasureALLOLEGNMESOSPY
Volatility, 1Y 83.5%72.5%57.3% 12.8%
Downside volatility, 1Y 83.3%62.7%55.1% 12.8%
Beta vs S&P 500, 1Y 1.910.481.52 1.00
Return / volatility, 1Y -0.15-0.48-0.22 0.80
Max drawdown, 5Y -95.3%-78.2%-87.9% -25.4%
From 52-week high -64.7%-41.8%-30.6% -3.5%
52-week high $3.06$36.28$20.96 $779.14
52-week low $1.05$16.65$11.95 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleALLOLEGNMESO
P/E now vs peer median -2.1xmedian 17.4x -42.4xmedian 17.4x -32.7xmedian 17.4x
P/S now vs peer median 80.4xmedian 8.9x 3.1xmedian 8.9x 15.7xmedian 8.9x
EV/EBITDA now vs peer median -0.2xmedian 17.0x 850.2xmedian 17.0x —median 17.0x
P/FCF now vs peer median -3.2xmedian 21.4x -60.2xmedian 21.4x -42.2xmedian 21.4x
P/B now vs peer median 0.9xmedian 2.1x 3.2xmedian 2.1x 3.3xmedian 2.1x
PEG now vs peer median -0.05median 0.35 -0.90median 0.35 —median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsALLOLEGNMESO
Revenue $4.64M $1.27B –
Gross profit – $727.10M –
Operating income -$180.32M -$55.25M –
Net income -$165.49M -$80.39M –
Free cash flow -$115.53M -$64.60M –
R&D $122.52M $396.15M –
EPS (diluted) $-0.50 $-0.50 –
Cash & equivalents $38.63M $672.90M $102.91M
Total debt – $156.40M $119.24M
Shares (diluted) 328.93M 184.32M 129.49M
Enterprise value -$723.62M $1.59B $1.41B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricALLOLEGNMESO
P/E -2.1x -42.4x -32.7x
P/FCF -3.2x -60.2x -42.2x
P/Operating cash flow -3.6x -43.5x –
P/S 80.4x 3.1x 15.7x
P/B 0.9x 3.2x 3.3x
P/Tangible book 0.9x 3.2x 3.3x
EV/EBITDA -0.2x 850.2x –
EV/EBIT -0.2x -61.0x –
EV/Revenue 8.7x 2.7x –
EV/FCF -0.3x -52.2x –
EV/Operating cash flow -0.4x -37.7x –
PEG (3Y EPS CAGR) -0.05 -0.90 –

Growth

14 metrics
MetricALLOLEGNMESO
Revenue growth (1Y) – 59.5% –
Revenue CAGR (3Y) 253.5% 97.6% –
Gross profit growth (1Y) – 42.4% –
Gross profit CAGR (3Y) – 147.5% –
Operating income growth (1Y) 29.1% 75.3% –
Operating income CAGR (3Y) 20.5% 49.1% –
Net income growth (1Y) 30.1% 75.3% –
Net income CAGR (3Y) 22.9% 46.7% –
EPS growth (1Y) 53.5% 72.0% –
EPS CAGR (3Y) 41.1% 47.0% –
Operating cash flow growth (1Y) 40.8% 67.5% –
Operating cash flow CAGR (3Y) 24.6% 37.1% –
Free cash flow growth (1Y) 38.0% 77.8% –
Free cash flow CAGR (3Y) 23.0% 44.5% –

Profitability

14 metrics
MetricALLOLEGNMESO
Gross margin – 57.2% –
EBITDA margin -3,634% 0.3% –
Operating margin -3,886% -4.3% –
Pretax margin -3,574% -4.4% –
Net margin -3,567% -7.2% –
FCF margin -2,490% -5.1% –
Operating cash flow margin -2,203% -7.0% –
Return on equity -46.4% -8.3% –
Return on assets -35.1% -5.5% –
Return on invested capital – -4.2% –
Return on capital employed -40.9% -4.3% –
Asset turnover 0.0x 0.8x –
Cash conversion (OCF / net income) 0.6x 1.1x –
Stock comp / revenue 808.0% 5.2% –

Financial Health

11 metrics
MetricALLOLEGNMESO
Debt / assets – 8.9% 15.4%
Debt / equity – 0.1x 0.2x
Net debt / EBITDA – -130.2x –
Debt / FCF – -2.4x –
Liabilities / assets 20.7% 29.8% 26.5%
Equity / assets 79.3% 70.2% 73.5%
Interest coverage -138.7x -4.8x –
Current ratio 10.7x 3.0x 2.4x
Quick ratio 10.5x 1.7x 2.0x
Cash ratio 10.5x 1.7x 1.3x
Altman Z-score -3.77 6.65 –

Shareholder Returns

7 metrics
MetricALLOLEGNMESO
Dividend yield – – –
Net buyback yield -0.2% -5.5% –
Shareholder yield -0.2% -5.5% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusALLOLEGNMESO
EPS, next fiscal year $-0.63FY2026 $-0.04FY2026 $-0.15FY2027
Revenue, next fiscal year $4.07MFY2026 $1.37BFY2026 $188.99MFY2027
Revenue growth, next FY – +32.9%FY2026 +57.2%FY2027
Revenue growth, the year after +207.8% +35.9% +110.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersALLOLEGNMESO
Held by institutions 90.5% 55.9% 3.0%
Institutions holding 209 218 73
Change in shares held, QoQ +69.5% +7.3% +17.7%
Institutions buying 133 117 34
Institutions selling 48 78 20
Buyers to sellers 2.77 1.50 1.70

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ALLOLEGNMESO
ALLO 1.00 0.09 0.17
LEGN 0.09 1.00 0.13
MESO 0.17 0.13 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, ALLO, LEGN and MESO?

Legend Biotech (LEGN) is the largest by market capitalisation: Allogene Therapeutics (ALLO) $378.27M, Legend Biotech (LEGN) $4.09B, Mesoblast (MESO) $1.84B.

Which company is more profitable?

Legend Biotech (LEGN) has the highest net margin (Allogene Therapeutics (ALLO) -3,566.7%, Legend Biotech (LEGN) -7.2%).

Which stock has performed better?

Over the past year Mesoblast (MESO) returned the most: Allogene Therapeutics (ALLO) -12.9%, Legend Biotech (LEGN) -34.9%, Mesoblast (MESO) -12.7%. Over five years, Mesoblast (MESO) compounded fastest (Allogene Therapeutics (ALLO) -44.3%/yr, Legend Biotech (LEGN) -16.4%/yr, Mesoblast (MESO) +3.1%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Mesoblast (MESO) has been the steadiest (Allogene Therapeutics (ALLO) 83.5%, Legend Biotech (LEGN) 72.5%, Mesoblast (MESO) 57.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ALLO, LEGN and MESO?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Legend Biotech (LEGN) leads on 3. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.