ALLO vs BEAM vs MESO Stock Comparison

Allogene Therapeutics, Beam Therapeutics and Mesoblast Prices as of Oct 28, 2026 Peers: Industry group
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BEAM Beam Therapeutics Inc.
$28.78 +18.8% 1M +8.9% 1Y
Market cap
$2.97B
P/E
–
Revenue (TTM)
$156.04M
Div. yield
–
Gene and Cell Therapy Healthcare
4 wins
MESO Mesoblast Ltd
$13.39 -7.7% 1M -20.0% 1Y
Market cap
$1.73B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins

Head to Head

6 decided of 12

Beam Therapeutics leads on 4 of the 12 questions below (Beam Therapeutics 4, Mesoblast 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionALLOBEAMMESOLeader
Larger companyMarket capitalisation $448.95M $2.97B $1.73B BEAM
Cheaper on earningsLower P/E, profitable companies only -2.6x -35.1x -30.2x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months — +158.9% — –
More profitableNet margin, trailing twelve months -3,566.7% -54.7% — BEAM
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — 3.0x — –
Higher dividend yieldTrailing dividend yield — 0.00% — –
Better 1-year returnPrice return, last 12 months +3.2% +8.9% -20.0% BEAM
Better 5-year returnAnnualised price return, 5 years -40.4%/yr -20.2%/yr +2.0%/yr MESO
Less volatileAnnualised volatility, 1 year 82.8% 70.7% 54.8% MESO
Higher overall scoreMean of the five percentile scores vs peers 55/100 69/100 — BEAM

Percentile Scorecard

ALLOBEAMMESO

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisALLOBEAMMESO
Valuation 19 #504 of 625 57 #272 of 625 71 #185 of 625
Growth 91 #58 of 602 77 #139 of 602 –
Profitability 25 #415 of 549 64 #197 of 549 –
Financial Health 63 #243 of 654 81 #123 of 654 44 #364 of 654
Shareholder Returns 80 #76 of 367 68 #119 of 367 –
Overall 55 69 –
  • ALLO ranked among 672 companies in Pharmaceuticals and Biotechnology
  • BEAM ranked among 672 companies in Pharmaceuticals and Biotechnology
  • MESO ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodALLOBEAMMESOSPY
1 month -20.2%+18.8%-7.7% +0.9%
3 months -28.2%+10.6%-5.2% +5.9%
6 months -38.4%-2.0%-13.9% +8.5%
Year to date -5.1%+3.8%-25.8% +13.3%
1 year +3.2%+8.9%-20.0% +12.4%
3 years -48.6%+54.6%+472.2% +88.1%
3 years, per year -19.9%+15.6%+78.9% +23.5%
5 years -92.5%-67.6%+10.7% +68.2%
5 years, per year -40.4%-20.2%+2.0% +11.0%
10 years ——+55.0% +263.4%
10 years, per year ——+4.5% +13.8%

Risk

MeasureALLOBEAMMESOSPY
Volatility, 1Y 82.8%70.7%54.8% 12.7%
Downside volatility, 1Y 82.1%64.0%54.9% 12.7%
Beta vs S&P 500, 1Y 1.842.091.53 1.00
Return / volatility, 1Y 0.040.13-0.36 0.98
Max drawdown, 5Y -95.3%-85.3%-87.9% -25.4%
From 52-week high -57.5%-24.1%-36.1% -0.9%
52-week high $3.06$37.92$20.96 $779.14
52-week low $1.05$20.60$11.95 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleALLOBEAMMESO
P/E now vs peer median -2.6xmedian 17.4x -35.1xmedian 17.4x -30.2xmedian 17.4x
P/S now vs peer median 96.8xmedian 9.1x 19.0xmedian 9.1x 14.4xmedian 9.1x
EV/EBITDA now vs peer median -0.7xmedian 17.1x -5.4xmedian 17.1x —median 17.1x
P/FCF now vs peer median -3.9xmedian 19.0x -8.0xmedian 19.0x -38.8xmedian 19.0x
P/B now vs peer median 1.0xmedian 2.2x 2.8xmedian 2.2x 3.1xmedian 2.2x
PEG now vs peer median -0.06median 0.34 -0.83median 0.34 —median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsALLOBEAMMESO
Revenue $4.64M $156.04M –
Operating income -$180.32M -$378.02M –
Net income -$165.49M -$86.52M –
Free cash flow -$115.53M -$372.77M –
R&D $122.52M $408.66M –
EPS (diluted) $-0.50 $-0.82 –
Cash & equivalents $38.63M $219.83M $102.91M
Total debt – $100.26M $119.24M
Shares (diluted) 328.93M 104.33M 129.49M
Enterprise value -$652.94M -$1.71B $1.30B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricALLOBEAMMESO
P/E -2.6x -35.1x -30.2x
P/FCF -3.9x -8.0x -38.8x
P/Operating cash flow -4.4x -8.3x –
P/S 96.8x 19.0x 14.4x
P/B 1.0x 2.8x 3.1x
P/Tangible book 1.0x 2.8x 3.1x
EV/EBITDA -0.7x -5.4x –
EV/EBIT -0.6x -5.1x –
EV/Revenue 25.1x 12.3x –
EV/FCF -1.0x -5.1x –
EV/Operating cash flow -1.1x -5.3x –
PEG (3Y EPS CAGR) -0.06 -0.83 –

Growth

14 metrics
MetricALLOBEAMMESO
Revenue growth (1Y) – 158.9% –
Revenue CAGR (3Y) 253.5% 24.9% –
Gross profit growth (1Y) – – –
Gross profit CAGR (3Y) – – –
Operating income growth (1Y) 29.1% 15.2% –
Operating income CAGR (3Y) 20.5% 0.3% –
Net income growth (1Y) 30.1% 78.2% –
Net income CAGR (3Y) 22.9% 35.8% –
EPS growth (1Y) 53.5% 79.0% –
EPS CAGR (3Y) 41.1% 42.4% –
Operating cash flow growth (1Y) 40.8% -4.2% –
Operating cash flow CAGR (3Y) 24.6% -2.0% –
Free cash flow growth (1Y) 38.0% -4.8% –
Free cash flow CAGR (3Y) 23.0% 0.7% –

Profitability

14 metrics
MetricALLOBEAMMESO
Gross margin – – –
EBITDA margin -3,634% -228.0% –
Operating margin -3,886% -242.3% –
Pretax margin -3,574% -54.4% –
Net margin -3,567% -54.7% –
FCF margin -2,490% -238.9% –
Operating cash flow margin -2,203% -230.3% –
Return on equity -46.4% -7.6% –
Return on assets -35.1% -5.9% –
Return on invested capital – – –
Return on capital employed -40.9% -27.9% –
Asset turnover 0.0x 0.1x –
Cash conversion (OCF / net income) 0.6x 4.2x –
Stock comp / revenue 808.0% 52.2% –

Financial Health

11 metrics
MetricALLOBEAMMESO
Debt / assets – 7.2% 15.4%
Debt / equity – 0.1x 0.2x
Net debt / EBITDA – 3.0x –
Debt / FCF – -0.3x –
Liabilities / assets 20.7% 23.0% 26.5%
Equity / assets 79.3% 77.0% 73.5%
Interest coverage -138.7x – –
Current ratio 10.7x 14.6x 2.4x
Quick ratio 10.5x 14.3x 2.0x
Cash ratio 10.5x 14.3x 1.3x
Altman Z-score -3.37 3.84 –

Shareholder Returns

7 metrics
MetricALLOBEAMMESO
Dividend yield – – –
Net buyback yield -0.2% -0.5% –
Shareholder yield -0.2% -0.5% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusALLOBEAMMESO
EPS, next fiscal year $-0.63FY2026 $-4.22FY2026 $-0.15FY2027
Revenue, next fiscal year $4.07MFY2026 $49.46MFY2026 $188.99MFY2027
Revenue growth, next FY – -64.6%FY2026 +57.2%FY2027
Revenue growth, the year after +207.8% +23.6% +110.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersALLOBEAMMESO
Held by institutions 90.5% 100.0% 3.0%
Institutions holding 209 277 73
Change in shares held, QoQ +69.8% +1.0% +17.7%
Institutions buying 133 154 34
Institutions selling 48 75 20
Buyers to sellers 2.77 2.05 1.70

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ALLOBEAMMESO
ALLO 1.00 0.39 0.19
BEAM 0.39 1.00 0.14
MESO 0.19 0.14 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, ALLO, BEAM and MESO?

Beam Therapeutics (BEAM) is the largest by market capitalisation: Allogene Therapeutics (ALLO) $448.95M, Beam Therapeutics (BEAM) $2.97B, Mesoblast (MESO) $1.73B.

Which company is more profitable?

Beam Therapeutics (BEAM) has the highest net margin (Allogene Therapeutics (ALLO) -3,566.7%, Beam Therapeutics (BEAM) -54.7%).

Which stock has performed better?

Over the past year Beam Therapeutics (BEAM) returned the most: Allogene Therapeutics (ALLO) +3.2%, Beam Therapeutics (BEAM) +8.9%, Mesoblast (MESO) -20.0%. Over five years, Mesoblast (MESO) compounded fastest (Allogene Therapeutics (ALLO) -40.4%/yr, Beam Therapeutics (BEAM) -20.2%/yr, Mesoblast (MESO) +2.0%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Mesoblast (MESO) has been the steadiest (Allogene Therapeutics (ALLO) 82.8%, Beam Therapeutics (BEAM) 70.7%, Mesoblast (MESO) 54.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ALLO, BEAM and MESO?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Beam Therapeutics (BEAM) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.