ALGN vs MLSS vs PAIYY Stock Comparison

Align Technology, Milestone Scientific and Aesthetic Medical International Holdings Prices as of Nov 5, 2026 Peers: Industry group
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ALGN Align Technology Inc
$159.37 +12.7% 1M +16.2% 1Y
Market cap
$11.68B
P/E
23.7x
Revenue (TTM)
$4.16B
Div. yield
–
Dental Healthcare
5 wins

Head to Head

5 decided of 12

Align Technology leads on 5 of the 12 questions below (Align Technology 5). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionALGNMLSSPAIYYLeader
Larger companyMarket capitalisation $11.68B $28.00M $491.09K ALGN
Cheaper on earningsLower P/E, profitable companies only 23.7x — -0.1x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 14.6x — — –
Faster revenue growthRevenue growth, trailing twelve months +4.4% -27.5% — ALGN
More profitableNet margin, trailing twelve months 11.8% — — –
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% — –
Better 1-year returnPrice return, last 12 months +16.2% -27.6% -94.1% ALGN
Better 5-year returnAnnualised price return, 5 years -25.4%/yr -33.7%/yr -70.1%/yr ALGN
Less volatileAnnualised volatility, 1 year 40.1% 81.0% 418.3% ALGN
Higher overall scoreMean of the five percentile scores vs peers 69/100 — — –

Percentile Scorecard

ALGNMLSSPAIYY

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisALGNMLSSPAIYY
Valuation 89 #27 of 229 – 26 #71 of 95
Growth 34 #146 of 221 – –
Profitability 88 #27 of 210 – –
Financial Health 46 #131 of 240 – 9 #91 of 100
Shareholder Returns 91 #14 of 147 – –
Overall 69 – –
  • ALGN ranked among 247 companies in Medical Devices and Diagnostics
  • MLSS ranked among 247 companies in Medical Devices and Diagnostics
  • PAIYY ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodALGNMLSSPAIYYSPY
1 month +12.7%-18.9%-50.0% -5.9%
3 months -5.7%-34.8%-50.0% -4.6%
6 months -5.4%-36.0%-80.0% +0.2%
Year to date +2.1%+9.9%-94.1% +7.5%
1 year +16.2%-27.6%-94.1% +8.2%
3 years -19.4%-63.9%-98.4% +68.3%
3 years, per year -6.9%-28.8%-74.6% +19.0%
5 years -76.8%-87.1%-99.8% +56.5%
5 years, per year -25.4%-33.7%-70.1% +9.4%
10 years +85.9%-83.8%— +251.5%
10 years, per year +6.4%-16.6%— +13.4%

Risk

MeasureALGNMLSSPAIYYSPY
Volatility, 1Y 40.1%81.0%418.3% 13.6%
Downside volatility, 1Y 37.6%82.2%1,242.8% 14.2%
Beta vs S&P 500, 1Y 1.331.09-3.67 1.00
Return / volatility, 1Y 0.40-0.34-0.22 0.60
Max drawdown, 5Y -82.4%-90.9%-99.8% -25.4%
From 52-week high -19.3%-45.5%-96.9% -5.9%
52-week high $197.51$0.55$0.32 $779.14
52-week low $132.28$0.25$0.01 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleALGNMLSSPAIYY
P/E now vs peer median 23.0xmedian 26.9x —median 26.9x -0.1xmedian 24.8x
P/S now vs peer median 2.7xmedian 2.9x 4.0xmedian 2.9x 0.0xmedian 1.6x
EV/EBITDA now vs peer median 11.8xmedian 17.5x —median 17.5x —median 15.9x
P/FCF now vs peer median 18.7xmedian 26.4x —median 26.4x -0.2xmedian 20.9x
P/B now vs peer median 2.6xmedian 2.3x —median 2.3x -0.1xmedian 3.3x
PEG now vs peer median 1.69median 0.88 —median 0.88 —median 0.88

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsALGNMLSSPAIYY
Revenue $4.16B $6.58M –
Gross profit $2.88B – –
Operating income $620.46M – –
Net income $491.87M – –
Free cash flow $602.50M – –
R&D $377.60M – –
EPS (diluted) $6.93 – –
Cash & equivalents $1.14B – $8.61M
Total debt – – $20.62M
Shares (diluted) 71.02M 93.13M 47.83M
Enterprise value $7.28B $28.00M -$20.49M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricALGNMLSSPAIYY
P/E 23.0x – -0.1x
P/FCF 18.7x – -0.2x
P/Operating cash flow 15.0x – –
P/S 2.7x 4.0x 0.0x
P/B 2.6x – -0.1x
P/Tangible book 2.7x – -0.1x
EV/EBITDA 11.8x – –
EV/EBIT 16.3x – –
EV/Revenue 2.4x 4.0x –
EV/FCF 16.8x – –
EV/Operating cash flow 13.5x – –
PEG (3Y EPS CAGR) 1.69 – –

Growth

14 metrics
MetricALGNMLSSPAIYY
Revenue growth (1Y) 4.4% -27.5% –
Revenue CAGR (3Y) 3.0% -12.9% –
Gross profit growth (1Y) 5.5% – –
Gross profit CAGR (3Y) 2.7% – –
Operating income growth (1Y) 16.1% – –
Operating income CAGR (3Y) 2.0% – –
Net income growth (1Y) 30.0% – –
Net income CAGR (3Y) 10.7% – –
EPS growth (1Y) 32.6% – –
EPS CAGR (3Y) 13.6% – –
Operating cash flow growth (1Y) 14.3% – –
Operating cash flow CAGR (3Y) -5.3% – –
Free cash flow growth (1Y) 6.3% – –
Free cash flow CAGR (3Y) -4.2% – –

Profitability

14 metrics
MetricALGNMLSSPAIYY
Gross margin 69.1% – –
EBITDA margin 20.6% – –
Operating margin 14.9% – –
Pretax margin 15.5% – –
Net margin 11.8% – –
FCF margin 14.5% – –
Operating cash flow margin 18.0% – –
Return on equity 11.5% – –
Return on assets 7.6% – –
Return on invested capital – – –
Return on capital employed 13.6% – –
Asset turnover 0.6x – –
Cash conversion (OCF / net income) 1.5x – –
Stock comp / revenue 4.1% – –

Financial Health

11 metrics
MetricALGNMLSSPAIYY
Debt / assets – – 28.2%
Debt / equity – – -3.3x
Net debt / EBITDA – – –
Debt / FCF – – –
Liabilities / assets 34.0% – 108.5%
Equity / assets 66.0% – -8.5%
Interest coverage – – –
Current ratio 1.4x – 0.3x
Quick ratio 1.2x – 0.3x
Cash ratio 0.6x – 0.1x
Altman Z-score 4.72 – –

Shareholder Returns

7 metrics
MetricALGNMLSSPAIYY
Dividend yield – – –
Net buyback yield 2.5% – –
Shareholder yield 2.5% – –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusALGNMLSSPAIYY
Forward P/E 14.6xFY2026 – –
EPS, next fiscal year $10.88FY2026 $-0.04FY2026 $-1.50FY2023
EPS growth, next FY +3.5%FY2026 – –
EPS growth, the year after +16.5% – –
Revenue, next fiscal year $3.84BFY2026 $9.29MFY2026 $89.98MFY2023
Revenue growth, next FY -4.7%FY2026 +3.6%FY2026 –
Revenue growth, the year after +3.3% +27.1% –

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersALGNMLSSPAIYY
Held by institutions 100.0% 5.8% –
Institutions holding 678 31 –
Change in shares held, QoQ +4.2% +18.9% –
Institutions buying 293 11 –
Institutions selling 268 4 –
Buyers to sellers 1.09 2.75 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ALGNMLSSPAIYY
ALGN 1.00 0.20 -0.04
MLSS 0.20 1.00 0.05
PAIYY -0.04 0.05 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, ALGN, MLSS and PAIYY?

Align Technology (ALGN) is the largest by market capitalisation: Align Technology (ALGN) $11.68B, Milestone Scientific (MLSS) $28.00M, Aesthetic Medical International Holdings (PAIYY) $491.09K.

Which company is growing faster?

Align Technology (ALGN) grew revenue fastest over the trailing twelve months: Align Technology (ALGN) +4.4%, Milestone Scientific (MLSS) -27.5%.

Which stock has performed better?

Over the past year Align Technology (ALGN) returned the most: Align Technology (ALGN) +16.2%, Milestone Scientific (MLSS) -27.6%, Aesthetic Medical International Holdings (PAIYY) -94.1%. Over five years, Align Technology (ALGN) compounded fastest (Align Technology (ALGN) -25.4%/yr, Milestone Scientific (MLSS) -33.7%/yr, Aesthetic Medical International Holdings (PAIYY) -70.1%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Align Technology (ALGN) has been the steadiest (Align Technology (ALGN) 40.1%, Milestone Scientific (MLSS) 81.0%, Aesthetic Medical International Holdings (PAIYY) 418.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ALGN, MLSS and PAIYY?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Align Technology (ALGN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.