ALC vs ISRG vs SKYA Stock Comparison

Alcon, Intuitive Surgical and SkyAI Prices as of Nov 3, 2026 Peers: Industry group
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ALC Alcon Inc
$72.37 +13.5% 1M -2.0% 1Y
Market cap
$38.12B
P/E
59.3x
Revenue (TTM)
$10.80B
Div. yield
–
Medical Devices Healthcare
2 wins
ISRG Intuitive Surgical Inc
$440.75 +12.5% 1M -19.0% 1Y
Market cap
$168.86B
P/E
57.1x
Revenue (TTM)
$11.58B
Div. yield
–
Medical Devices Healthcare
5 wins
SKYA SkyAI, Inc.
$2.95 +60.3% 1M -31.1% 1Y
Market cap
$212.68M
P/E
–
Revenue (TTM)
$174.18K
Div. yield
–
Medical Supplies Healthcare
2 wins

Head to Head

9 decided of 12

Intuitive Surgical leads on 5 of the 12 questions below (Intuitive Surgical 5, SkyAI 2, Alcon 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionALCISRGSKYALeader
Larger companyMarket capitalisation $38.12B $168.86B $212.68M ISRG
Cheaper on earningsLower P/E, profitable companies only 59.3x 57.1x -0.5x ISRG
Cheaper on forward earningsLower price / next fiscal year consensus EPS 22.5x 38.4x 0.0x SKYA
Faster revenue growthRevenue growth, trailing twelve months +8.5% +20.5% +108.0% SKYA
More profitableNet margin, trailing twelve months 6.0% 25.5% -228,220.7% ISRG
Better return on capitalReturn on invested capital 3.6% — — –
Less leveragedLower net debt / EBITDA — — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -2.0% -19.0% -31.1% ALC
Better 5-year returnAnnualised price return, 5 years -3.4%/yr +3.9%/yr — ISRG
Less volatileAnnualised volatility, 1 year 28.8% 34.7% 105.3% ALC
Higher overall scoreMean of the five percentile scores vs peers 68/100 80/100 27/100 ISRG

Percentile Scorecard

ALCISRGSKYA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisALCISRGSKYA
Valuation 77 #53 of 229 50 #114 of 229 4 #220 of 229
Growth 48 #115 of 221 81 #42 of 221 4 #212 of 221
Profitability 76 #51 of 209 97 #7 of 209 1 #208 of 209
Financial Health 62 #93 of 240 79 #51 of 240 95 #13 of 240
Shareholder Returns 77 #34 of 147 92 #13 of 147 34 #98 of 147
Overall 68 80 27
  • ALC ranked among 248 companies in Medical Devices and Diagnostics
  • ISRG ranked among 248 companies in Medical Devices and Diagnostics
  • SKYA ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodALCISRGSKYASPY
1 month +13.5%+12.5%+60.3% -2.0%
3 months +1.9%+19.7%+126.9% -2.2%
6 months -2.8%-2.4%+55.3% +4.2%
Year to date -8.2%-22.2%+45.3% +10.6%
1 year -2.0%-19.0%-31.1% +10.4%
3 years -2.6%+58.2%-99.9% +73.6%
3 years, per year -0.9%+16.5%-90.0% +20.2%
5 years -15.7%+21.3%— +61.6%
5 years, per year -3.4%+3.9%— +10.1%
10 years —+489.2%— +261.3%
10 years, per year —+19.4%— +13.7%

Risk

MeasureALCISRGSKYASPY
Volatility, 1Y 28.8%34.7%105.3% 12.8%
Downside volatility, 1Y 29.0%37.8%104.8% 12.8%
Beta vs S&P 500, 1Y 0.360.902.49 1.00
Return / volatility, 1Y -0.07-0.55-0.30 0.81
Max drawdown, 5Y -38.4%-49.9%-100.0% -25.4%
From 52-week high -17.0%-25.7%-31.1% -3.2%
52-week high $87.18$592.85$4.28 $779.14
52-week low $62.02$332.02$0.95 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleALCISRGSKYA
P/E now vs peer median 55.5xmedian 28.1x 52.0xmedian 28.1x -0.5xmedian 28.1x
P/S now vs peer median 3.3xmedian 2.9x 13.2xmedian 2.9x 1,221xmedian 2.9x
EV/EBITDA now vs peer median —median 18.0x 36.4xmedian 18.0x -0.5xmedian 18.0x
P/FCF now vs peer median 20.3xmedian 24.8x 42.5xmedian 24.8x -1.1xmedian 24.8x
P/B now vs peer median 1.6xmedian 2.3x 9.5xmedian 2.3x 1.4xmedian 2.3x
PEG now vs peer median 2.65median 0.95 2.02median 0.95 0.01median 0.95

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsALCISRGSKYA
Revenue $10.80B $11.58B $174.18K
Gross profit $6.17B $7.78B $324.68K
Operating income $948.00M $3.28B -$374.36M
Net income $643.00M $2.97B -$397.51M
Free cash flow $1.74B $3.60B -$201.93M
R&D $1.43B $1.49B $475.55K
EPS (diluted) $1.30 $8.41 $-5.51
Cash & equivalents $1.36B $2.98B $12.07M
Total debt $4.72B – –
Shares (diluted) 496.20M 351.60M 72.09M
Enterprise value $29.08B $149.15B $167.38M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricALCISRGSKYA
P/E 55.5x 52.0x -0.5x
P/FCF 20.3x 42.5x -1.1x
P/Operating cash flow 15.3x 37.4x -14.8x
P/S 3.3x 13.2x 1,221x
P/B 1.6x 9.5x 1.4x
P/Tangible book 2.6x 10.2x 16.4x
EV/EBITDA – 36.4x -0.5x
EV/EBIT 39.9x 45.3x -0.5x
EV/Revenue 3.5x 12.8x 1,152x
EV/FCF 21.8x 41.3x -1.0x
EV/Operating cash flow 16.4x 36.4x -13.9x
PEG (3Y EPS CAGR) 2.65 2.02 0.01

Growth

14 metrics
MetricALCISRGSKYA
Revenue growth (1Y) 8.5% 20.5% 108.0%
Revenue CAGR (3Y) 5.9% 19.1% 19.4%
Gross profit growth (1Y) 11.7% 21.9% –
Gross profit CAGR (3Y) 7.3% 19.5% –
Operating income growth (1Y) -34.3% 16.6% -8,055%
Operating income CAGR (3Y) 7.5% 24.8% -240.7%
Net income growth (1Y) -40.1% 7.5% -54,854%
Net income CAGR (3Y) 21.1% 24.4% -268.2%
EPS growth (1Y) -40.7% 10.8% -658.6%
EPS CAGR (3Y) 21.0% 25.7% -100.6%
Operating cash flow growth (1Y) 10.3% 38.1% -356.8%
Operating cash flow CAGR (3Y) 25.9% 26.4% -24.4%
Free cash flow growth (1Y) 7.5% 58.4% -6,031%
Free cash flow CAGR (3Y) 48.0% 42.0% -196.9%

Profitability

14 metrics
MetricALCISRGSKYA
Gross margin 57.2% 67.2% 186.4%
EBITDA margin – 35.3% -214,892%
Operating margin 8.8% 28.4% -214,931%
Pretax margin 6.9% 31.3% -221,236%
Net margin 6.0% 25.5% -228,221%
FCF margin 16.1% 31.1% -115,934%
Operating cash flow margin 21.4% 35.3% -8,259%
Return on equity 2.9% 17.3% -280.7%
Return on assets 2.1% 14.8% -276.3%
Return on invested capital 3.6% – –
Return on capital employed 3.4% 18.7% -223.1%
Asset turnover 0.3x 0.6x 0.0x
Cash conversion (OCF / net income) 3.6x 1.4x 0.0x
Stock comp / revenue 1.6% 7.2% 52,451%

Financial Health

11 metrics
MetricALCISRGSKYA
Debt / assets 15.2% – –
Debt / equity 0.2x – –
Net debt / EBITDA – – –
Debt / FCF 2.7x – –
Liabilities / assets 30.6% 16.7% 1.9%
Equity / assets 69.4% 83.3% 98.1%
Interest coverage 9.2x – –
Current ratio 2.1x 3.3x 5.3x
Quick ratio 1.3x 2.3x 4.4x
Cash ratio 0.7x 1.6x 4.2x
Altman Z-score – 30.22 30.23

Shareholder Returns

7 metrics
MetricALCISRGSKYA
Dividend yield 0.4% – –
Net buyback yield 2.6% 2.8% -0.6%
Shareholder yield 3.0% 2.8% -0.6%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusALCISRGSKYA
Forward P/E 22.5xFY2026 38.4xFY2026 0.0xFY2026
EPS, next fiscal year $3.22FY2026 $11.47FY2026 $2,362.06FY2026
EPS growth, next FY +7.7%FY2026 +28.4%FY2026 –
EPS growth, the year after +15.5% +4.5% –
Revenue, next fiscal year $10.50BFY2026 $11.60BFY2026 $70.01MFY2026
Revenue growth, next FY +4.3%FY2026 +15.3%FY2026 +34,200.1%FY2026
Revenue growth, the year after +8.1% +11.3% +17.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersALCISRGSKYA
Held by institutions 48.8% 86.2% –
Institutions holding 631 2,240 –
Change in shares held, QoQ +5.3% +4.6% –
Institutions buying 227 1,073 –
Institutions selling 274 878 –
Buyers to sellers 0.83 1.22 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ALCISRGSKYA
ALC 1.00 0.39 0.09
ISRG 0.39 1.00 0.14
SKYA 0.09 0.14 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, ALC, ISRG and SKYA?

Intuitive Surgical (ISRG) is the largest by market capitalisation: Alcon (ALC) $38.12B, Intuitive Surgical (ISRG) $168.86B, SkyAI (SKYA) $212.68M.

Which stock is cheaper, ALC, ISRG and SKYA?

Intuitive Surgical (ISRG) trades on the lowest price-to-earnings ratio (Alcon (ALC) 59.3x, Intuitive Surgical (ISRG) 57.1x, SkyAI (SKYA) -0.5x). On next year's consensus earnings, SkyAI (SKYA) is cheapest (Alcon (ALC) 22.5x, Intuitive Surgical (ISRG) 38.4x, SkyAI (SKYA) 0.0x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

SkyAI (SKYA) grew revenue fastest over the trailing twelve months: Alcon (ALC) +8.5%, Intuitive Surgical (ISRG) +20.5%, SkyAI (SKYA) +108.0%.

Which company is more profitable?

Intuitive Surgical (ISRG) has the highest net margin (Alcon (ALC) 6.0%, Intuitive Surgical (ISRG) 25.5%, SkyAI (SKYA) -228,220.7%).

Which stock has performed better?

Over the past year Alcon (ALC) returned the most: Alcon (ALC) -2.0%, Intuitive Surgical (ISRG) -19.0%, SkyAI (SKYA) -31.1%. Over five years, Intuitive Surgical (ISRG) compounded fastest (Alcon (ALC) -3.4%/yr, Intuitive Surgical (ISRG) +3.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Alcon (ALC) has been the steadiest (Alcon (ALC) 28.8%, Intuitive Surgical (ISRG) 34.7%, SkyAI (SKYA) 105.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ALC, ISRG and SKYA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Intuitive Surgical (ISRG) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.