ABVX vs VRTX vs ARGX Stock Comparison

Abivax, Vertex Pharmaceuticals and Argenx Se Prices as of Oct 28, 2026 Peers: Industry group
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ABVX Abivax S.A.
$89.84 -7.2% 1M -4.7% 1Y
Market cap
$6.17B
P/E
–
Revenue (TTM)
-$76.25M
Div. yield
–
Biotechnology Healthcare
ARGX Argenx Se
$891.76 -8.3% 1M +6.6% 1Y
Market cap
$55.00B
P/E
29.3x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
4 wins

Head to Head

9 decided of 12

Vertex Pharmaceuticals leads on 5 of the 12 questions below (Vertex Pharmaceuticals 5, Argenx Se 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionABVXVRTXARGXLeader
Larger companyMarket capitalisation $6.17B $137.16B $55.00B VRTX
Cheaper on earningsLower P/E, profitable companies only -13.2x 31.1x 29.3x ARGX
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 29.0x 29.1x VRTX
Faster revenue growthRevenue growth, trailing twelve months -463.2% +10.2% +61.5% ARGX
More profitableNet margin, trailing twelve months — 35.0% 32.3% VRTX
Better return on capitalReturn on invested capital -74.9% — — –
Less leveragedLower net debt / EBITDA 1.4x — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -4.7% +25.4% +6.6% VRTX
Better 5-year returnAnnualised price return, 5 years — +23.4%/yr +24.2%/yr ARGX
Less volatileAnnualised volatility, 1 year 91.1% 29.0% 36.9% VRTX
Higher overall scoreMean of the five percentile scores vs peers 55/100 76/100 92/100 ARGX

Percentile Scorecard

ABVXVRTXARGX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisABVXVRTXARGX
Valuation 73 #169 of 625 80 #124 of 625 84 #101 of 625
Growth 8 #554 of 602 60 #241 of 602 94 #35 of 602
Profitability 26 #408 of 549 95 #30 of 549 98 #11 of 549
Financial Health 82 #121 of 654 54 #304 of 654 –
Shareholder Returns 89 #43 of 367 93 #28 of 367 –
Overall 55 76 92
  • ABVX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • VRTX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • ARGX ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodABVXVRTXARGXSPY
1 month -7.2%+0.4%-8.3% +0.9%
3 months -24.4%+9.6%+1.0% +5.9%
6 months -15.4%+25.2%+14.9% +8.5%
Year to date -33.4%+16.8%+6.0% +13.3%
1 year -4.7%+25.4%+6.6% +12.4%
3 years +868.1%+49.1%+93.9% +88.1%
3 years, per year +113.2%+14.3%+24.7% +23.5%
5 years —+186.4%+195.3% +68.2%
5 years, per year —+23.4%+24.2% +11.0%
10 years —+582.8%— +263.4%
10 years, per year —+21.2%— +13.8%

Risk

MeasureABVXVRTXARGXSPY
Volatility, 1Y 91.1%29.0%36.9% 12.7%
Downside volatility, 1Y 94.5%25.8%34.6% 12.7%
Beta vs S&P 500, 1Y 0.960.500.39 1.00
Return / volatility, 1Y -0.050.870.18 0.98
Max drawdown, 5Y -67.5%-29.1%-38.2% -25.4%
From 52-week high -38.2%-5.1%-15.8% -0.9%
52-week high $145.31$557.96$1,058.90 $779.14
52-week low $72.50$409.47$663.93 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleABVXVRTXARGX
P/E now vs peer median -13.3xmedian 17.4x 30.5xmedian 17.4x 29.1xmedian 17.4x
P/S now vs peer median -92.5xmedian 9.1x 10.7xmedian 9.1x 9.5xmedian 9.1x
EV/EBITDA now vs peer median -19.4xmedian 17.1x 25.3xmedian 17.1x —median 17.1x
P/FCF now vs peer median -30.6xmedian 19.0x 35.4xmedian 19.0x —median 19.0x
P/B now vs peer median 16.9xmedian 2.2x 6.6xmedian 2.2x —median 2.2x
PEG now vs peer median —median 0.34 3.01median 0.34 0.28median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsABVXVRTXARGX
Revenue -$76.25M $12.59B $5.82B
Gross profit – $10.82B $5.24B
Operating income -$341.36M $4.78B $1.74B
Net income -$467.93M $4.41B $1.88B
Free cash flow -$230.23M $3.80B –
R&D $242.27M $3.91B $1.80B
EPS (diluted) $-6.73 $17.26 $28.43
Cash & equivalents $443.17M $6.14B –
Total debt $156.48K – –
Shares (diluted) 69.53M 255.20M 66.03M
Enterprise value $3.81B $109.17B $55.00B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricABVXVRTXARGX
P/E -13.3x 30.5x 29.1x
P/FCF -30.6x 35.4x –
P/Operating cash flow -30.7x 31.3x –
P/S -92.5x 10.7x 9.5x
P/B 16.9x 6.6x –
P/Tangible book 17.2x 6.8x –
EV/EBITDA -19.4x 25.3x –
EV/EBIT -19.3x 26.4x 31.7x
EV/Revenue -86.4x 10.0x 9.5x
EV/FCF -28.6x 33.3x –
EV/Operating cash flow -28.6x 29.4x –
PEG (3Y EPS CAGR) – 3.01 0.28

Growth

14 metrics
MetricABVXVRTXARGX
Revenue growth (1Y) -463.2% 10.2% 61.5%
Revenue CAGR (3Y) – 9.8% 80.5%
Gross profit growth (1Y) – 10.1% 62.2%
Gross profit CAGR (3Y) – 9.0% 80.0%
Operating income growth (1Y) 0.2% 21.8% 120.6%
Operating income CAGR (3Y) – 6.4% 85.1%
Net income growth (1Y) -120.1% 21.1% 22.5%
Net income CAGR (3Y) – 9.4% 115.5%
EPS growth (1Y) -99.6% 22.9% 20.9%
EPS CAGR (3Y) – 10.1% 104.8%
Operating cash flow growth (1Y) -56.0% 11.6% –
Operating cash flow CAGR (3Y) – 1.8% –
Free cash flow growth (1Y) -55.6% 8.5% –
Free cash flow CAGR (3Y) – -0.7% –

Profitability

14 metrics
MetricABVXVRTXARGX
Gross margin – 86.0% 90.0%
EBITDA margin – 39.7% –
Operating margin – 38.0% 29.9%
Pretax margin – 41.9% 32.6%
Net margin – 35.0% 32.3%
FCF margin – 30.2% –
Operating cash flow margin 301.6% 34.1% –
Return on equity -102.8% 22.2% –
Return on assets -81.0% 16.3% –
Return on invested capital -74.9% – –
Return on capital employed -68.9% 20.8% –
Asset turnover -0.1x 0.5x –
Cash conversion (OCF / net income) 0.5x 1.0x –
Stock comp / revenue -97.6% 5.5% –

Financial Health

11 metrics
MetricABVXVRTXARGX
Debt / assets 0.0% – –
Debt / equity 0.0x – –
Net debt / EBITDA 1.4x – –
Debt / FCF 0.0x – –
Liabilities / assets 20.8% 26.2% –
Equity / assets 79.2% 73.8% –
Interest coverage -4.1x – 10,120x
Current ratio 6.0x 3.2x –
Quick ratio 5.7x 2.5x –
Cash ratio 5.7x 2.0x –
Altman Z-score 35.16 13.43 –

Shareholder Returns

7 metrics
MetricABVXVRTXARGX
Dividend yield – – –
Net buyback yield 0.0% 1.4% –
Shareholder yield 0.0% 1.4% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusABVXVRTXARGX
Forward P/E – 29.0xFY2026 29.1xFY2026
EPS, next fiscal year $-4.42FY2026 $18.24FY2026 $30.63FY2026
EPS growth, next FY – -0.9%FY2026 +56.5%FY2026
EPS growth, the year after – +23.0% +26.9%
Revenue, next fiscal year $5.07MFY2026 $12.67BFY2026 $6.08BFY2026
Revenue growth, next FY -5.0%FY2026 +5.8%FY2026 +43.1%FY2026
Revenue growth, the year after +1,467.2% +18.8% +22.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersABVXVRTXARGX
Held by institutions 79.0% 95.1% 46.1%
Institutions holding 301 1,745 504
Change in shares held, QoQ +10.1% +3.9% -2.0%
Institutions buying 189 902 264
Institutions selling 99 605 160
Buyers to sellers 1.91 1.49 1.65

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ABVXVRTXARGX
ABVX 1.00 0.23 0.26
VRTX 0.23 1.00 0.35
ARGX 0.26 0.35 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ABVX, VRTX and ARGX?

Vertex Pharmaceuticals (VRTX) is the largest by market capitalisation: Abivax (ABVX) $6.17B, Vertex Pharmaceuticals (VRTX) $137.16B, Argenx Se (ARGX) $55.00B.

Which stock is cheaper, ABVX, VRTX and ARGX?

Argenx Se (ARGX) trades on the lowest price-to-earnings ratio (Abivax (ABVX) -13.2x, Vertex Pharmaceuticals (VRTX) 31.1x, Argenx Se (ARGX) 29.3x). On next year's consensus earnings, Vertex Pharmaceuticals (VRTX) is cheapest (Vertex Pharmaceuticals (VRTX) 29.0x, Argenx Se (ARGX) 29.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Abivax (ABVX) -463.2%, Vertex Pharmaceuticals (VRTX) +10.2%, Argenx Se (ARGX) +61.5%.

Which company is more profitable?

Vertex Pharmaceuticals (VRTX) has the highest net margin (Vertex Pharmaceuticals (VRTX) 35.0%, Argenx Se (ARGX) 32.3%).

Which stock has performed better?

Over the past year Vertex Pharmaceuticals (VRTX) returned the most: Abivax (ABVX) -4.7%, Vertex Pharmaceuticals (VRTX) +25.4%, Argenx Se (ARGX) +6.6%. Over five years, Argenx Se (ARGX) compounded fastest (Vertex Pharmaceuticals (VRTX) +23.4%/yr, Argenx Se (ARGX) +24.2%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Vertex Pharmaceuticals (VRTX) has been the steadiest (Abivax (ABVX) 91.1%, Vertex Pharmaceuticals (VRTX) 29.0%, Argenx Se (ARGX) 36.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ABVX, VRTX and ARGX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Vertex Pharmaceuticals (VRTX) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.