ABVX vs ARGX vs ALNY Stock Comparison

Abivax, Argenx Se and Alnylam Pharmaceuticals Prices as of Oct 29, 2026 Peers: Industry group
1 more company in this comparison (VRTX) Create a free account to keep reading and compare up to 10 companies.
ABVX Abivax S.A.
$89.06 -9.6% 1M -10.0% 1Y
Market cap
$6.00B
P/E
–
Revenue (TTM)
-$76.25M
Div. yield
–
Biotechnology Healthcare
ARGX Argenx Se
$897.85 -7.5% 1M +9.2% 1Y
Market cap
$54.86B
P/E
29.2x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
7 wins

Head to Head

8 decided of 12

Argenx Se leads on 7 of the 12 questions below (Argenx Se 7, Alnylam Pharmaceuticals 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionABVXARGXALNYLeader
Larger companyMarket capitalisation $6.00B $54.86B $22.31B ARGX
Cheaper on earningsLower P/E, profitable companies only -12.8x 29.2x 46.3x ARGX
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 29.3x 25.7x ALNY
Faster revenue growthRevenue growth, trailing twelve months -463.2% +61.5% +60.8% ARGX
More profitableNet margin, trailing twelve months — 32.3% — –
Better return on capitalReturn on invested capital -74.9% — — –
Less leveragedLower net debt / EBITDA 1.4x — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -10.0% +9.2% -63.9% ARGX
Better 5-year returnAnnualised price return, 5 years — +24.4%/yr +1.7%/yr ARGX
Less volatileAnnualised volatility, 1 year 91.0% 36.9% 58.8% ARGX
Higher overall scoreMean of the five percentile scores vs peers 55/100 92/100 65/100 ARGX

Percentile Scorecard

ABVXARGXALNY

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisABVXARGXALNY
Valuation 73 #167 of 624 83 #108 of 624 70 #187 of 624
Growth 8 #553 of 601 95 #34 of 601 96 #27 of 601
Profitability 26 #400 of 541 98 #11 of 541 –
Financial Health 82 #120 of 647 – 29 #463 of 647
Shareholder Returns 88 #43 of 359 – –
Overall 55 92 65
  • ABVX ranked among 671 companies in Pharmaceuticals and Biotechnology
  • ARGX ranked among 671 companies in Pharmaceuticals and Biotechnology
  • ALNY ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodABVXARGXALNYSPY
1 month -9.6%-7.5%-31.5% +0.7%
3 months -28.4%+2.9%-15.3% +3.7%
6 months -24.1%+14.9%-43.8% +7.1%
Year to date -34.0%+6.8%-56.2% +12.8%
1 year -10.0%+9.2%-63.9% +11.9%
3 years +865.9%+93.4%+14.9% +85.2%
3 years, per year +113.1%+24.6%+4.7% +22.8%
5 years —+197.3%+9.0% +67.6%
5 years, per year —+24.4%+1.7% +10.9%
10 years ——+378.8% +262.0%
10 years, per year ——+17.0% +13.7%

Risk

MeasureABVXARGXALNYSPY
Volatility, 1Y 91.0%36.9%58.8% 12.7%
Downside volatility, 1Y 94.2%34.7%74.8% 12.6%
Beta vs S&P 500, 1Y 0.960.390.42 1.00
Return / volatility, 1Y -0.110.25-1.09 0.94
Max drawdown, 5Y -67.5%-38.2%-64.6% -25.4%
From 52-week high -38.7%-15.2%-63.9% -1.2%
52-week high $145.31$1,058.90$481.59 $779.14
52-week low $72.50$663.93$174.00 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleABVXARGXALNY
P/E now vs peer median -13.2xmedian 17.8x 29.3xmedian 17.8x 46.3xmedian 17.8x
P/S now vs peer median -91.7xmedian 9.1x 9.5xmedian 9.1x 4.6xmedian 9.1x
EV/EBITDA now vs peer median -19.2xmedian 15.0x —median 15.0x —median 15.0x
P/FCF now vs peer median -30.4xmedian 21.7x —median 21.7x 41.4xmedian 21.7x
P/B now vs peer median 16.7xmedian 2.2x —median 2.2x 6.5xmedian 2.2x
PEG now vs peer median —median 0.35 0.28median 0.35 —median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsABVXARGXALNY
Revenue -$76.25M $5.82B $5.01B
Gross profit – $5.24B –
Operating income -$341.36M $1.74B $977.59M
Net income -$467.93M $1.88B –
Free cash flow -$230.23M – –
R&D $242.27M $1.80B $1.56B
EPS (diluted) $-6.73 $28.43 –
Cash & equivalents $443.17M – $1.75B
Total debt $156.48K – –
Shares (diluted) 69.53M 66.03M 138.28M
Enterprise value $3.64B $54.86B $22.31B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricABVXARGXALNY
P/E -13.2x 29.3x 46.3x
P/FCF -30.4x – 41.4x
P/Operating cash flow -30.4x – –
P/S -91.7x 9.5x 4.6x
P/B 16.7x – 6.5x
P/Tangible book 17.0x – 6.5x
EV/EBITDA -19.2x – –
EV/EBIT -19.1x 31.9x –
EV/Revenue -85.6x 9.5x 4.6x
EV/FCF -28.3x – –
EV/Operating cash flow -28.4x – –
PEG (3Y EPS CAGR) – 0.28 –

Growth

14 metrics
MetricABVXARGXALNY
Revenue growth (1Y) -463.2% 61.5% 60.8%
Revenue CAGR (3Y) – 80.5% 42.7%
Gross profit growth (1Y) – 62.2% –
Gross profit CAGR (3Y) – 80.0% –
Operating income growth (1Y) 0.2% 120.6% 269.3%
Operating income CAGR (3Y) – 85.1% 68.2%
Net income growth (1Y) -120.1% 22.5% –
Net income CAGR (3Y) – 115.5% –
EPS growth (1Y) -99.6% 20.9% –
EPS CAGR (3Y) – 104.8% –
Operating cash flow growth (1Y) -56.0% – –
Operating cash flow CAGR (3Y) – – –
Free cash flow growth (1Y) -55.6% – –
Free cash flow CAGR (3Y) – – –

Profitability

14 metrics
MetricABVXARGXALNY
Gross margin – 90.0% –
EBITDA margin – – –
Operating margin – 29.9% –
Pretax margin – 32.6% –
Net margin – 32.3% –
FCF margin – – –
Operating cash flow margin 301.6% – –
Return on equity -102.8% – –
Return on assets -81.0% – –
Return on invested capital -74.9% – –
Return on capital employed -68.9% – –
Asset turnover -0.1x – 0.7x
Cash conversion (OCF / net income) 0.5x – –
Stock comp / revenue -97.6% – –

Financial Health

11 metrics
MetricABVXARGXALNY
Debt / assets 0.0% – –
Debt / equity 0.0x – –
Net debt / EBITDA 1.4x – –
Debt / FCF 0.0x – –
Liabilities / assets 20.8% – 54.9%
Equity / assets 79.2% – 45.1%
Interest coverage -4.1x 10,120x –
Current ratio 6.0x – 2.5x
Quick ratio 5.7x – –
Cash ratio 5.7x – –
Altman Z-score 34.82 – –

Shareholder Returns

7 metrics
MetricABVXARGXALNY
Dividend yield – – –
Net buyback yield 0.0% – –
Shareholder yield 0.0% – –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusABVXARGXALNY
Forward P/E – 29.3xFY2026 25.7xFY2026
EPS, next fiscal year $-4.42FY2026 $30.63FY2026 $6.76FY2026
EPS growth, next FY – +56.5%FY2026 +190.1%FY2026
EPS growth, the year after – +26.9% +34.3%
Revenue, next fiscal year $5.07MFY2026 $6.08BFY2026 $5.68BFY2026
Revenue growth, next FY -5.0%FY2026 +43.1%FY2026 +53.1%FY2026
Revenue growth, the year after +1,467.2% +22.9% +27.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersABVXARGXALNY
Held by institutions – 46.1% 99.7%
Institutions holding – 505 787
Change in shares held, QoQ – -2.0% +3.8%
Institutions buying – 264 412
Institutions selling – 161 278
Buyers to sellers – 1.64 1.48

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ABVXARGXALNY
ABVX 1.00 0.26 0.12
ARGX 0.26 1.00 0.15
ALNY 0.12 0.15 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ABVX, ARGX and ALNY?

Argenx Se (ARGX) is the largest by market capitalisation: Abivax (ABVX) $6.00B, Argenx Se (ARGX) $54.86B, Alnylam Pharmaceuticals (ALNY) $22.31B.

Which stock is cheaper, ABVX, ARGX and ALNY?

Argenx Se (ARGX) trades on the lowest price-to-earnings ratio (Abivax (ABVX) -12.8x, Argenx Se (ARGX) 29.2x, Alnylam Pharmaceuticals (ALNY) 46.3x). On next year's consensus earnings, Alnylam Pharmaceuticals (ALNY) is cheapest (Argenx Se (ARGX) 29.3x, Alnylam Pharmaceuticals (ALNY) 25.7x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Abivax (ABVX) -463.2%, Argenx Se (ARGX) +61.5%, Alnylam Pharmaceuticals (ALNY) +60.8%.

Which stock has performed better?

Over the past year Argenx Se (ARGX) returned the most: Abivax (ABVX) -10.0%, Argenx Se (ARGX) +9.2%, Alnylam Pharmaceuticals (ALNY) -63.9%. Over five years, Argenx Se (ARGX) compounded fastest (Argenx Se (ARGX) +24.4%/yr, Alnylam Pharmaceuticals (ALNY) +1.7%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Argenx Se (ARGX) has been the steadiest (Abivax (ABVX) 91.0%, Argenx Se (ARGX) 36.9%, Alnylam Pharmaceuticals (ALNY) 58.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ABVX, ARGX and ALNY?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Argenx Se (ARGX) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.