ABT vs ISRG vs PFE Stock Comparison

Abbott Laboratories, Intuitive Surgical and Pfizer Prices as of Nov 2, 2026 Peers: Industry group
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ABT Abbott Laboratories
$110.27 +13.1% 1M -10.8% 1Y
Market cap
$190.81B
P/E
35.4x
Revenue (TTM)
$46.59B
Div. yield
2.29%
Medical Devices Healthcare
2 wins
ISRG Intuitive Surgical Inc
$436.87 +11.5% 1M -18.2% 1Y
Market cap
$151.42B
P/E
51.6x
Revenue (TTM)
$11.58B
Div. yield
–
Medical Devices Healthcare
4 wins
PFE Pfizer Inc
$30.71 +10.5% 1M +24.6% 1Y
Market cap
$175.04B
P/E
40.4x
Revenue (TTM)
$63.70B
Div. yield
5.60%
Pharmaceuticals Healthcare
6 wins

Head to Head

12 decided of 12

Pfizer leads on 6 of the 12 questions below (Pfizer 6, Intuitive Surgical 4, Abbott Laboratories 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionABTISRGPFELeader
Larger companyMarket capitalisation $190.81B $151.42B $175.04B ABT
Cheaper on earningsLower P/E, profitable companies only 35.4x 51.6x 40.4x ABT
Cheaper on forward earningsLower price / next fiscal year consensus EPS 19.4x 38.1x 10.8x PFE
Faster revenue growthRevenue growth, trailing twelve months +8.1% +20.5% -0.2% ISRG
More profitableNet margin, trailing twelve months 11.6% 25.5% 6.8% ISRG
Better return on capitalReturn on invested capital 6.2% — 13.4% PFE
Less leveragedLower net debt / EBITDA 2.5x — 1.9x PFE
Higher dividend yieldTrailing dividend yield 2.29% — 5.60% PFE
Better 1-year returnPrice return, last 12 months -10.8% -18.2% +24.6% PFE
Better 5-year returnAnnualised price return, 5 years -3.0%/yr +3.9%/yr -7.3%/yr ISRG
Less volatileAnnualised volatility, 1 year 27.8% 34.8% 21.7% PFE
Higher overall scoreMean of the five percentile scores vs peers 57/100 79/100 65/100 ISRG

Percentile Scorecard

ABTISRGPFE

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisABTISRGPFE
Valuation 67 #76 of 227 50 #113 of 227 94 #37 of 623
Growth 28 #158 of 220 79 #47 of 220 24 #460 of 601
Profitability 85 #33 of 209 97 #7 of 209 92 #46 of 553
Financial Health 37 #152 of 240 78 #54 of 240 25 #493 of 654
Shareholder Returns 66 #47 of 138 92 #12 of 138 90 #38 of 367
Overall 57 79 65
  • ABT ranked among 247 companies in Medical Devices and Diagnostics
  • ISRG ranked among 247 companies in Medical Devices and Diagnostics
  • PFE ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodABTISRGPFESPY
1 month +13.1%+11.5%+10.5% -2.3%
3 months +2.9%+16.4%+22.6% -0.7%
6 months +26.0%-3.4%+16.8% +4.8%
Year to date -12.0%-22.9%+23.3% +10.3%
1 year -10.8%-18.2%+24.6% +10.3%
3 years +15.1%+56.9%-1.8% +73.0%
3 years, per year +4.8%+16.2%-0.6% +20.1%
5 years -14.3%+20.9%-31.5% +61.9%
5 years, per year -3.0%+3.9%-7.3% +10.1%
10 years +184.9%+489.9%+0.3% +258.6%
10 years, per year +11.0%+19.4%+0.0% +13.6%

Risk

MeasureABTISRGPFESPY
Volatility, 1Y 27.8%34.8%21.7% 12.8%
Downside volatility, 1Y 27.6%37.8%21.1% 12.8%
Beta vs S&P 500, 1Y -0.040.900.20 1.00
Return / volatility, 1Y -0.39-0.521.13 0.80
Max drawdown, 5Y -41.6%-49.9%-64.8% -25.4%
From 52-week high -15.6%-26.3%0.0% -3.5%
52-week high $130.59$592.85$30.71 $779.14
52-week low $82.56$332.02$23.67 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleABTISRGPFE
P/E now vs peer median 35.4xmedian 28.4x 51.6xmedian 28.4x 40.4xmedian 17.4x
P/S now vs peer median 4.1xmedian 3.0x 13.1xmedian 3.0x 2.7xmedian 8.9x
EV/EBITDA now vs peer median 20.2xmedian 18.0x 36.0xmedian 18.0x 8.4xmedian 17.0x
P/FCF now vs peer median 24.4xmedian 25.0x 42.1xmedian 25.0x 15.9xmedian 21.4x
P/B now vs peer median 3.7xmedian 2.3x 9.4xmedian 2.3x 2.0xmedian 2.1x
PEG now vs peer median 19.46median 0.93 2.01median 0.93 -0.98median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsABTISRGPFE
Revenue $46.59B $11.58B $63.70B
Gross profit $26.37B $7.78B $46.61B
Operating income $7.35B $3.28B $20.39B
Net income $5.43B $2.97B $4.36B
Free cash flow $7.82B $3.60B $10.99B
R&D $3.16B $1.49B $11.05B
EPS (diluted) $3.11 $8.41 $0.76
Cash & equivalents $5.10B $2.98B $976.00M
Total debt $32.61B – $63.19B
Shares (diluted) 1.74B 351.60M 5.70B
Enterprise value $161.89B $131.84B $121.98B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricABTISRGPFE
P/E 35.4x 51.6x 40.4x
P/FCF 24.4x 42.1x 15.9x
P/Operating cash flow 19.3x 37.0x 13.1x
P/S 4.1x 13.1x 2.7x
P/B 3.7x 9.4x 2.0x
P/Tangible book 5.5x 10.2x 4.6x
EV/EBITDA 20.2x 36.0x 8.4x
EV/EBIT 29.7x 44.9x 11.1x
EV/Revenue 4.7x 12.7x 3.6x
EV/FCF 27.8x 41.0x 20.6x
EV/Operating cash flow 22.0x 36.0x 16.9x
PEG (3Y EPS CAGR) 19.46 2.01 -0.98

Growth

14 metrics
MetricABTISRGPFE
Revenue growth (1Y) 8.1% 20.5% -0.2%
Revenue CAGR (3Y) 5.0% 19.1% -7.0%
Gross profit growth (1Y) 9.2% 21.9% 1.2%
Gross profit CAGR (3Y) 5.9% 19.5% -5.6%
Operating income growth (1Y) -2.2% 16.6% 1.5%
Operating income CAGR (3Y) 6.2% 24.8% -9.9%
Net income growth (1Y) -61.2% 7.5% -59.6%
Net income CAGR (3Y) 1.7% 24.4% -41.3%
EPS growth (1Y) -61.0% 10.8% -59.7%
EPS CAGR (3Y) 1.8% 25.7% -41.3%
Operating cash flow growth (1Y) 9.6% 38.1% -11.8%
Operating cash flow CAGR (3Y) 9.9% 26.4% -2.7%
Free cash flow growth (1Y) 15.5% 58.4% -11.7%
Free cash flow CAGR (3Y) 12.5% 42.0% 1.0%

Profitability

14 metrics
MetricABTISRGPFE
Gross margin 56.6% 67.2% 73.2%
EBITDA margin 23.2% 35.3% 42.4%
Operating margin 15.8% 28.4% 32.0%
Pretax margin 16.1% 31.3% 6.6%
Net margin 11.6% 25.5% 6.8%
FCF margin 16.8% 31.1% 17.2%
Operating cash flow margin 21.3% 35.3% 21.0%
Return on equity 10.4% 17.3% 5.0%
Return on assets 4.9% 14.8% 2.1%
Return on invested capital 6.2% – 13.4%
Return on capital employed 8.0% 18.7% 11.9%
Asset turnover 0.4x 0.6x 0.3x
Cash conversion (OCF / net income) 1.8x 1.4x 3.1x
Stock comp / revenue 1.5% 7.2% 1.5%

Financial Health

11 metrics
MetricABTISRGPFE
Debt / assets 29.9% – 31.4%
Debt / equity 0.6x – 0.7x
Net debt / EBITDA 2.5x – 1.9x
Debt / FCF 4.2x – 5.8x
Liabilities / assets 52.6% 16.7% 57.5%
Equity / assets 47.4% 83.3% 42.5%
Interest coverage 9.6x – –
Current ratio 1.4x 3.3x 1.3x
Quick ratio 0.8x 2.3x 0.7x
Cash ratio 0.3x 1.6x 0.4x
Altman Z-score 3.35 29.97 2.39

Shareholder Returns

7 metrics
MetricABTISRGPFE
Dividend yield 2.3% – 5.6%
Net buyback yield 0.9% 2.8% –
Shareholder yield 3.1% 2.8% 5.6%
Payout ratio (earnings) 78.5% – 224.5%
Payout ratio (FCF) 54.5% – 89.1%
Dividend growth (1Y) 7.2% – 1.5%
Dividend CAGR (3Y) 7.5% – 2.4%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusABTISRGPFE
Forward P/E 19.4xFY2026 38.1xFY2026 10.8xFY2026
EPS, next fiscal year $5.69FY2026 $11.47FY2026 $2.85FY2026
EPS growth, next FY +10.5%FY2026 +28.4%FY2026 -11.5%FY2026
EPS growth, the year after +10.4% +4.5% -4.6%
Revenue, next fiscal year $53.00BFY2026 $11.60BFY2026 $60.59BFY2026
Revenue growth, next FY +19.5%FY2026 +15.3%FY2026 -3.2%FY2026
Revenue growth, the year after -2.2% +11.3% +3.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersABTISRGPFE
Held by institutions 79.2% 86.2% 66.9%
Institutions holding 2,982 2,238 2,838
Change in shares held, QoQ +0.3% +4.6% +2.0%
Institutions buying 1,260 1,072 1,326
Institutions selling 1,379 878 1,205
Buyers to sellers 0.91 1.22 1.10

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ABTISRGPFE
ABT 1.00 0.32 0.22
ISRG 0.32 1.00 0.21
PFE 0.22 0.21 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ABT, ISRG and PFE?

Abbott Laboratories (ABT) is the largest by market capitalisation: Abbott Laboratories (ABT) $190.81B, Intuitive Surgical (ISRG) $151.42B, Pfizer (PFE) $175.04B.

Which stock is cheaper, ABT, ISRG and PFE?

Abbott Laboratories (ABT) trades on the lowest price-to-earnings ratio (Abbott Laboratories (ABT) 35.4x, Intuitive Surgical (ISRG) 51.6x, Pfizer (PFE) 40.4x). On next year's consensus earnings, Pfizer (PFE) is cheapest (Abbott Laboratories (ABT) 19.4x, Intuitive Surgical (ISRG) 38.1x, Pfizer (PFE) 10.8x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Intuitive Surgical (ISRG) grew revenue fastest over the trailing twelve months: Abbott Laboratories (ABT) +8.1%, Intuitive Surgical (ISRG) +20.5%, Pfizer (PFE) -0.2%.

Which company is more profitable?

Intuitive Surgical (ISRG) has the highest net margin (Abbott Laboratories (ABT) 11.6%, Intuitive Surgical (ISRG) 25.5%, Pfizer (PFE) 6.8%). On return on invested capital, Pfizer (PFE) leads (Abbott Laboratories (ABT) 6.2%, Pfizer (PFE) 13.4%).

Which stock has performed better?

Over the past year Pfizer (PFE) returned the most: Abbott Laboratories (ABT) -10.8%, Intuitive Surgical (ISRG) -18.2%, Pfizer (PFE) +24.6%. Over five years, Intuitive Surgical (ISRG) compounded fastest (Abbott Laboratories (ABT) -3.0%/yr, Intuitive Surgical (ISRG) +3.9%/yr, Pfizer (PFE) -7.3%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Pfizer (PFE) has the highest dividend yield: Abbott Laboratories (ABT) 2.29%, Pfizer (PFE) 5.60%. Intuitive Surgical (ISRG) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Pfizer (PFE) has been the steadiest (Abbott Laboratories (ABT) 27.8%, Intuitive Surgical (ISRG) 34.8%, Pfizer (PFE) 21.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ABT, ISRG and PFE?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Pfizer (PFE) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.