Zai Lab Ltd (ZLAB) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

98,788,571Shares Outstanding

1,050,059Shares held by institutions

$21,043,182Value of institutional holdings

39.95%Institutional ownership %

-2.13%Shares Changed QoQ

121No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Recent 13F filings as of December 2025 show that 117 institutional investors hold a position in Zai Lab Ltd (NASDAQ:ZLAB).

Institutional ownership in Zai Lab edged down to 26.1% in December 2025, compared to 32.5% in September 2025.
Quarterly data indicates a 19.98% shift in institutional share volume, and the annual owner count reflects a decrease of 10.00%.
Among the 117 institutional holders of Zai Lab, 66 added to their stakes while 35 trimmed their positions and 16 held steady.
The aggregate institutional position in Zai Lab now stands at 28.39Mn shares as of December 2025, after investors increased their holdings (up by 4.73Mn shares quarter on quarter which is down 27.95Mn shares year over year).
With 6.96Mn shares, RTW INVESTMENTS, LP commands the largest institutional position in Zai Lab as of December 31, 2025, equating to 6.39% of the company.
Among the most significant buyers of Zai Lab during December 2025 were RTW INVESTMENTS, LP (4.67Mn), UBS Group AG (1.48Mn), CITADEL ADVISORS LLC (700.80K), JANE STREET GROUP, LLC (459.36K), ADAR1 Capital Management, LLC (377.74K).
Leading sellers of Zai Lab stock in December 2025 included FMR LLC (3.26Mn), Clearbridge Investments, LLC (1.71Mn), WELLINGTON MANAGEMENT GROUP LLP (965.60K), LMR Partners LLP (122.35K), ENVESTNET ASSET MANAGEMENT INC (100.71K).
The top 10 institutional holders of Zai Lab for the quarter ending December 2025 included RTW INVESTMENTS, LP (6.96Mn), Frazier Life Sciences Management, L.P. (1.90Mn), Clearbridge Investments, LLC (1.81Mn), UBS Group AG (1.78Mn), CITADEL ADVISORS LLC (1.69Mn), FMR LLC (1.44Mn), BAMCO INC /NY/ (1.42Mn), ADAR1 Capital Management, LLC (1.25Mn), Rock Springs Capital Management LP (811.55K), WELLINGTON MANAGEMENT GROUP LLP (752.86K).

117 Institutional Holders

1,050,059 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
RTW INVESTMENTS, LP	31 Dec, 2025	6,959,032	4,667,660	203.71%	$122,757,324.00
Frazier Life Sciences Management, L.P.	31 Dec, 2025	1,902,320	275,000	16.90%	$33,556,925.00
Clearbridge Investments, LLC	31 Dec, 2025	1,808,035	-1,711,302	-48.63%	$31,893,740.00
UBS Group AG	31 Dec, 2025	1,782,252	1,475,698	481.38%	$31,438,925.00
CITADEL ADVISORS LLC	31 Dec, 2025	1,687,846	700,803	71.00%	$29,773,604.00
FMR LLC	31 Dec, 2025	1,440,406	-3,261,305	-69.36%	$25,408,762.00
BAMCO INC /NY/	31 Dec, 2025	1,418,005	46,762	3.41%	$25,013,608.00
ADAR1 Capital Management, LLC	31 Dec, 2025	1,246,520	377,740	43.48%	$21,988,613.00
Rock Springs Capital Management LP	31 Dec, 2025	811,546	20,353	2.57%	$14,315,671.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	752,858	-965,597	-56.19%	$13,280,417.00
BlackRock, Inc.	31 Dec, 2025	635,213	161,650	34.13%	$11,205,157.00
JANE STREET GROUP, LLC	31 Dec, 2025	577,562	459,362	388.63%	$10,188,194.00
C WorldWide Group Holding A/S	31 Dec, 2025	510,000	0	0.00%	$8,996.00
B Group, Inc.	31 Dec, 2025	400,000	0	0.00%	$7,056,000.00
BANK OF AMERICA CORP /DE/	31 Dec, 2025	388,769	246,395	173.06%	$6,857,886.00
Legal & General Group Plc	31 Dec, 2025	387,800	5,341	1.40%	$6,842,649.00
Walleye Capital LLC	31 Dec, 2025	373,399	373,399	0.00%	$6,586,758.00
SCHRODER INVESTMENT MANAGEMENT GROUP	31 Dec, 2025	299,844	142,783	90.91%	$5,286,250.00
JPMORGAN CHASE & CO	31 Dec, 2025	293,703	284,296	3,022.17%	$5,180,921.00
MORGAN STANLEY	31 Dec, 2025	289,705	169,825	141.66%	$5,110,397.00

1 - 20 of 117

Research Tools