Xeris Biopharma Holdings, Inc. (XERS) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

1,857,264Shares held by institutions

$10,419,251Value of institutional holdings

55.18%Institutional ownership %

0.94%Shares Changed QoQ

199No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Xeris Biopharma Holdings, Inc. (NASDAQ:XERS) has 218 institutional investors that have filed 13F reports for the period ending December 2025.

Collectively, these holders controlled 55.6% of Xeris Biopharma Holdings's outstanding shares in December 2025, down from 56.1% in September 2025.
They increased total shares held in Xeris Biopharma Holdings by 4.21% from the prior quarter, while the number of investors in XERS increased 36.25% year over year.
During the quarter, 111 of these 218 funds increased positions in XERS, 74 reduced exposure, and 33 held steady.
Altogether, these fund groups held 98.67Mn shares in XERS by December 2025, up by 3.99Mn shares quarter on quarter, and up 26.39Mn shares year over year.
BlackRock, Inc. holds the largest position in XERS at 12.64Mn shares as of December 31, 2025, or 7.12% of shares outstanding.
Leading buyers of Xeris Biopharma Holdings shares for the quarter ending December 2025 were D. E. Shaw & Co., Inc. (1.73Mn), WELLINGTON MANAGEMENT GROUP LLP (1.71Mn), VANGUARD GROUP INC (1.36Mn), Granahan Investment Management, LLC (873.24K), NORGES BANK (800.7K).
The largest sellers of Xeris Biopharma Holdings for the quarter ending December 2025 were Bank Of America Corp /De/ (2.47Mn), UBS Group AG (1.18Mn), RENAISSANCE TECHNOLOGIES LLC (1.0Mn), Jpmorgan Chase & Co (915.09K), Prudential Financial Inc (815.26K).
Per Business Quant, the top 10 investors in XERS for the quarter ending December 2025 include BlackRock, Inc. (12.64Mn), VANGUARD GROUP INC (11.19Mn), D. E. Shaw & Co., Inc. (7.57Mn), GEODE CAPITAL MANAGEMENT, LLC (4.28Mn), State Street Corp (4.12Mn), Qube Research & Technologies Ltd (3.5Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (2.98Mn), Nuveen, LLC (2.81Mn), Morgan Stanley (2.71Mn), WELLINGTON MANAGEMENT GROUP LLP (2.29Mn).

218 Institutional Holders

1,857,264 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	711,619	5.97%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	1,358,760	13.83%	$0.00
Qube Research & Technologies Ltd	31 Dec, 2025	223,363	6.82%	$0.00
Barclays Plc	31 Dec, 2025	-308,360	-45.95%	$0.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	1,734,964	29.71%	$0.00
Nuveen, LLC	31 Dec, 2025	-21,068	-0.75%	$0.00
Rockefeller Capital Management L.P.	31 Dec, 2025	1,188	0.00%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	135,815	3.28%	$0.00
Rosalind Advisors, Inc.	31 Dec, 2025	315,934	17.59%	$0.00
State Street Corp	31 Dec, 2025	378,595	10.13%	$0.00
CenterBook Partners LP	31 Dec, 2025	693,386	99.31%	$0.00
DRIEHAUS CAPITAL MANAGEMENT LLC	31 Dec, 2025	361,438	13.80%	$0.00
Knott David M Jr	31 Dec, 2025	-45,000	-4.43%	$0.00
Morgan Stanley	31 Dec, 2025	-511,918	-15.90%	$0.00
Ishara Investments LP	31 Dec, 2025	800,000	0.00%	$0.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	1,705,636	293.59%	$0.00
Point72 Asset Management, L.P.	31 Dec, 2025	608,080	0.00%	$0.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	118,088	7.31%	$0.00
UBS Group AG	31 Dec, 2025	-1,180,900	-66.24%	$0.00
Goldman Sachs Group Inc	31 Dec, 2025	-227,034	-12.64%	$0.00

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