Xeris Biopharma Holdings, Inc. (XERS) Institutional Ownership

Ownership Summary

Recent 13F filings as of September 2025 show that 230 institutional investors hold a position in Xeris Biopharma Holdings, Inc. (NASDAQ:XERS).

• The percentage of Xeris Biopharma Holdings owned by institutions changed from 56.4% in June 2025 to 60.1% in September 2025, marking a slight up trend.
• Institutional share ownership changed by 7.86% QoQ, while the number of institutional owners saw an increase of 60.84% YoY.
• Of these 230 institutional investors, 128 increased their holdings in Xeris Biopharma Holdings, while 70 of them reduced positions, and 32 investors maintained their exposure.
• Collectively, institutional investors increased their stake in Xeris Biopharma Holdings to 97.06Mn shares as of September 2025, a change that is up by 7.07Mn shares quarter on quarter and up 33.14Mn shares year over year.
• With 11.93Mn shares, BlackRock, Inc. commands the largest institutional position in Xeris Biopharma Holdings as of September 30, 2025, equating to 7.39% of the company.
• Among the most significant buyers of Xeris Biopharma Holdings during September 2025 were D. E. Shaw & Co., Inc. (2.00Mn), UBS Group AG (1.55Mn), JANE STREET GROUP, LLC (901.89K), CHARLES SCHWAB INVESTMENT MANAGEMENT INC (879.08K), DEUTSCHE BANK AG\ (830.72K).
• Leading sellers of Xeris Biopharma Holdings stock in September 2025 included MILLENNIUM MANAGEMENT LLC (2.41Mn), CITADEL ADVISORS LLC (910.25K), CenterBook Partners LP (896.02K), GOLDMAN SACHS GROUP INC (476.03K), Legal & General Group Plc (446.78K).
• The top 10 institutional holders of Xeris Biopharma Holdings for the quarter ending September 2025 included BlackRock, Inc. (11.93Mn), VANGUARD GROUP INC (9.83Mn), D. E. Shaw & Co., Inc. (5.84Mn), GEODE CAPITAL MANAGEMENT, LLC (4.14Mn), STATE STREET CORP (3.74Mn), Qube Research & Technologies Ltd (3.27Mn), MORGAN STANLEY (3.22Mn), Nuveen, LLC (2.83Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (2.62Mn), Rosalind Advisors, Inc. (1.80Mn).