Wave Life Sciences Ltd. (WVE) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

168,287,500Shares Outstanding

8,569,905Shares held by institutions

$107,895,104Value of institutional holdings

104.64%Institutional ownership %

33.72%Shares Changed QoQ

209No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Wave Life Sciences Ltd. (NASDAQ:WVE) currently has 209 active institutional owners and shareholders as of today (December 2025), that have filed 13F forms with the Securities Exchange Commission (SEC).

Institutional ownership in Wave Life Sciences edged up to 104.6% in December 2025, compared to 85.9% in September 2025.
Quarterly data indicates a 33.72% shift in institutional share volume, and the annual owner count reflects an increase of 14.84%.
A review of institutional activity for Wave Life Sciences shows 143 of 209 filers increasing their positions, while 46 reduced their stake, and 20 remained unchanged.
Collectively, institutional investors increased their stake in Wave Life Sciences to 176.10Mn shares as of December 2025, a change that is up by 44.41Mn shares quarter on quarter and up 47.64Mn shares year over year.
With 18.25Mn shares, GSK plc commands the largest institutional position in Wave Life Sciences as of December 31, 2025, equating to 10.84% of the company.
Among the most significant buyers of Wave Life Sciences during December 2025 were GSK plc (18.25Mn), FMR LLC (10.01Mn), Darwin Global Management, Ltd. (7.30Mn), BlackRock, Inc. (2.22Mn), PRIMECAP MANAGEMENT CO/CA/ (2.20Mn).
Leading sellers of Wave Life Sciences stock in December 2025 included ADAGE CAPITAL PARTNERS GP, L.L.C. (4.78Mn), Bellevue Group AG (2.60Mn), Kynam Capital Management, LP (2.39Mn), Siren, L.L.C. (1.25Mn), LOOMIS SAYLES & CO L P (865.24K).
The top 10 institutional holders of Wave Life Sciences for the quarter ending December 2025 included GSK plc (18.25Mn), RA CAPITAL MANAGEMENT, L.P. (18.20Mn), FMR LLC (15.14Mn), BlackRock, Inc. (12.65Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (9.79Mn), MAVERICK CAPITAL LTD (9.28Mn), Darwin Global Management, Ltd. (7.30Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (6.58Mn), M28 Capital Management LP (5.66Mn), FEDERATED HERMES, INC. (4.74Mn).

209 Institutional Holders

8,569,905 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
GSK plc	31 Dec, 2025	18,245,691	18,245,691	0.00%	$310,176,747.00
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	18,203,009	1,000	0.01%	$309,451,153.00
FMR LLC	31 Dec, 2025	15,135,983	10,005,609	195.03%	$257,311,705.00
BlackRock, Inc.	31 Dec, 2025	12,648,907	2,218,094	21.26%	$215,031,419.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	9,786,061	-4,781,723	-32.82%	$166,363,037.00
MAVERICK CAPITAL LTD	31 Dec, 2025	9,280,237	888,381	10.59%	$157,764,029.00
Darwin Global Management, Ltd.	31 Dec, 2025	7,298,421	7,298,421	0.00%	$125,167,920.00
DRIEHAUS CAPITAL MANAGEMENT LLC	31 Dec, 2025	6,581,067	283,007	4.49%	$111,878,139.00
M28 Capital Management LP	31 Dec, 2025	5,664,548	0	0.00%	$96,297,316.00
FEDERATED HERMES, INC.	31 Dec, 2025	4,744,520	993,827	26.50%	$80,656,840.00
PRIMECAP MANAGEMENT CO/CA/	31 Dec, 2025	4,095,282	2,196,632	115.69%	$69,619,794.00
683 Capital Management, LLC	31 Dec, 2025	4,015,000	-135,000	-3.25%	$68,255,000.00
VANGUARD GROUP INC	31 Dec, 2025	3,573,746	433,910	13.82%	$60,753,682.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	3,170,110	251,740	8.63%	$53,902,133.00
STATE STREET CORP	31 Dec, 2025	2,996,084	149,718	5.26%	$50,933,428.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	2,854,082	728,945	34.30%	$48,519,394.00
Affinity Asset Advisors, LLC	31 Dec, 2025	2,700,000	600,000	28.57%	$45,900,000.00
EMERALD ADVISERS, LLC	31 Dec, 2025	2,455,089	-541,811	-18.08%	$41,736,513.00
Siren, L.L.C.	31 Dec, 2025	2,450,000	-1,246,322	-33.72%	$41,650,000.00
Kynam Capital Management, LP	31 Dec, 2025	2,169,105	-2,390,948	-52.43%	$36,874,785.00

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