Trevi Therapeutics, Inc. (TRVI) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

145,104,986Shares Outstanding

131,666,414Shares held by institutions

$1,982,896,195Value of institutional holdings

90.74%Institutional ownership %

-0.88%Shares Changed QoQ

182No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Trevi Therapeutics, Inc. (NASDAQ:TRVI) has 182 institutional investors that have filed 13F reports for the period ending December 2025.

Their combined ownership stood at 89.8% of outstanding shares in December 2025, down from 91.9% in September 2025.
Their total shares held in TRVI decreased -1.71% from the prior quarter, while the number of investors in Trevi Therapeutics increased 63.96% year over year.
Of these 182 funds, 105 grew their exposure to Trevi Therapeutics, 50 cut back, and 27 maintained positions.
Institutional investors collectively held 130.26Mn shares in Trevi Therapeutics as of December 2025, down by 2.27Mn shares quarter on quarter, and up 45.26Mn shares year over year.
Pictet Asset Management Holding SA holds the largest position in TRVI at 1.71Mn shares as of December 31, 2025, or 1.18% of shares outstanding.
The largest buyers of Trevi Therapeutics for the quarter ending December 2025 were Pictet Asset Management Holding SA (174.04K), TRUST CO OF TOLEDO NA /OH/ (95.0K), PSP Research LLC (30.0K), PEREGRINE CAPITAL MANAGEMENT LLC (22.77K), Maltin Wealth Management, Inc. (10.56K).
The largest sellers of Trevi Therapeutics for the quarter ending December 2025 were SG Americas Securities, LLC (96.51K), STRS OHIO (10.9K), OPPENHEIMER & CO INC (671), GAMMA Investing LLC (86), SIGNATUREFD, LLC (77).
According to Business Quant data, leading holders of TRVI for December 2025 are Pictet Asset Management Holding SA (1.71Mn), PEREGRINE CAPITAL MANAGEMENT LLC (530.45K), TRUST CO OF TOLEDO NA /OH/ (131.5K), OPPENHEIMER & CO INC (100.03K), PFS Partners, LLC (79.0K), PSP Research LLC (30.0K), SG Americas Securities, LLC (28.05K), Diversified Trust Co (23.48K), CHAPIN DAVIS, INC. (20.1K), NBC SECURITIES, INC. (17.0K).

182 Institutional Holders

131,666,414 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
NEA Management Company, LLC	31 Dec, 2025	13,222,228	0	0.00%	$165,542,295.00
Frazier Life Sciences Management, L.P.	31 Dec, 2025	10,259,409	0	0.00%	$128,447,801.00
BlackRock, Inc.	31 Dec, 2025	10,126,183	225,130	2.27%	$126,779,812.00
FMR LLC	31 Dec, 2025	6,500,009	3,200,118	96.98%	$81,380,117.00
VANGUARD GROUP INC	31 Dec, 2025	6,434,655	607,669	10.43%	$80,561,880.00
Vivo Capital, LLC	31 Dec, 2025	5,094,668	0	0.00%	$63,785,243.00
MARSHALL WACE, LLP	31 Dec, 2025	4,580,548	-261,203	-5.39%	$57,348,462.00
Rubric Capital Management LP	31 Dec, 2025	3,766,749	-4,765,111	-55.85%	$47,159,697.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	3,403,990	150,102	4.61%	$42,617,956.00
MPM BioImpact LLC	31 Dec, 2025	3,287,087	-119,868	-3.52%	$41,154,329.00
VIKING GLOBAL INVESTORS LP	31 Dec, 2025	3,198,644	-1,930,231	-37.63%	$40,047,023.00
ORBIMED ADVISORS LLC	31 Dec, 2025	3,190,700	-117,700	-3.56%	$39,947,564.00
ALLIANCEBERNSTEIN L.P.	31 Dec, 2025	3,082,986	-1,209,465	-28.18%	$38,598,985.00
Octagon Capital Advisors LP	31 Dec, 2025	2,815,000	0	0.00%	$35,243,800.00
EVENTIDE ASSET MANAGEMENT, LLC	31 Dec, 2025	2,622,306	1,240,982	89.84%	$32,831,271.00
State Street Corp	31 Dec, 2025	2,435,000	215,578	9.71%	$30,486,200.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,412,885	191,959	8.64%	$30,214,388.00
Siren, L.L.C.	31 Dec, 2025	2,286,867	-250,000	-9.85%	$28,631,575.00
Affinity Asset Advisors, LLC	31 Dec, 2025	2,150,172	-649,828	-23.21%	$26,920,153.00
ACORN CAPITAL ADVISORS, LLC	31 Dec, 2025	2,144,844	0	0.00%	$26,853,447.00

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