As of September 29, 2026, Trevi Therapeutics's top three insider holders are Scott D Sandell (TenPercentOwner, 11.37Mn shares), Paul Edward Walker (TenPercentOwner, 11.37Mn shares), Peter W. Sonsini (TenPercentOwner, 11.37Mn shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Carmen Chang | TenPercentOwner | 0 | 11,370,376 | 11,370,376 | 10.7% | 13 Apr, 2022 |
| 2 | Paul Edward Walker | TenPercentOwner | 0 | 11,370,376 | 11,370,376 | 10.7% | 13 Apr, 2022 |
| 3 | Scott D Sandell | TenPercentOwner | 0 | 11,370,376 | 11,370,376 | 10.7% | 13 Apr, 2022 |
| 4 | Mohamad Makhzoumi | TenPercentOwner | 0 | 11,370,376 | 11,370,376 | 10.7% | 13 Apr, 2022 |
| 5 | Ali Behbahani | TenPercentOwner | 0 | 11,370,376 | 11,370,376 | 10.7% | 13 Apr, 2022 |
| 6 | Anthony A. Jr. Florence | TenPercentOwner | 0 | 11,370,376 | 11,370,376 | 10.7% | 13 Apr, 2022 |
| 7 | Peter W. Sonsini | TenPercentOwner | 0 | 11,370,376 | 11,370,376 | 10.7% | 13 Apr, 2022 |
| 8 | Enterprise Associates 16, L.P. New | TenPercentOwner | 10,421,428 | 0 | 10,421,428 | 9.8% | 13 Apr, 2022 |
| 9 | Forest Baskett | TenPercentOwner | 0 | 10,421,428 | 10,421,428 | 9.8% | 13 Apr, 2022 |
| 10 | Gp A, Llc Tpg | Other | 0 | 3,824,883 | 3,824,883 | 3.6% | 06 Jul, 2022 |
| 11 | Edward T Mathers | Director | 0 | 948,948 | 948,948 | 0.9% | 13 Apr, 2022 |
| 12 | David P Meeker | Director | 352,489 | 0 | 352,489 | 0.3% | 29 Aug, 2024 |
| 13 | Thomas Sciascia | Chief Scientific Officer | 221,373 | 0 | 221,373 | 0.2% | 26 Mar, 2025 |
| 14 | Jennifer L Good | President Ceo | 213,313 | 0 | 213,313 | 0.2% | 25 Mar, 2025 |
| 15 | Farrell Simon | Chief Commercial Officer | 76,900 | 0 | 76,900 | 0.1% | 12 Mar, 2025 |
| 16 | Lisa Delfini | Chief Financial Officer | 64,660 | 0 | 64,660 | 0.1% | 10 Jan, 2025 |
| 17 | Christopher Galletta | Officer | 26,095 | 0 | 26,095 | 0.0% | 03 Dec, 2025 |
| 18 | Michael Thomas Heffernan | Director | 6,351 | 0 | 6,351 | 0.0% | 17 Sep, 2026 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 15 Sep, 2026 | Michael Thomas Heffernan | Director | Acquired M | 18,421 | $3.04 | $56.00K | 24,772 | Direct |
| 15 Sep, 2026 | Michael Thomas Heffernan | Director | Disposed S | 18,321 | $15.09 | $276.46K | 6,451 | Direct |
| 15 Sep, 2026 | Michael Thomas Heffernan | Director | Disposed S | 100 | $15.88 | $1.59K | 6,351 | Direct |
| 15 Sep, 2026 | Michael Thomas Heffernan | Director | Acquired M | 21,052 | $3.33 | $70.10K | 27,403 | Direct |
| 15 Sep, 2026 | Michael Thomas Heffernan | Director | Disposed S | 20,952 | $15.09 | $316.17K | 6,451 | Direct |
| 15 Sep, 2026 | Michael Thomas Heffernan | Director | Disposed S | 100 | $15.88 | $1.59K | 6,351 | Direct |
| 15 Sep, 2026 | Michael Thomas Heffernan | Director | Disposed M | 18,421 | $0.00 | $0 | 0 | Direct |
| 15 Sep, 2026 | Michael Thomas Heffernan | Director | Disposed M | 21,052 | $0.00 | $0 | 0 | Direct |
| 03 Jun, 2026 | Michael Thomas Heffernan | Director | Acquired A | 35,000 | $0.00 | $0 | 35,000 | Direct |
| 03 Jun, 2026 | Edward T Mathers | Director | Acquired A | 35,000 | $0.00 | $0 | 35,000 | Direct |
| 03 Jun, 2026 | Anne Vanlent | Director | Acquired A | 35,000 | $0.00 | $0 | 35,000 | Direct |
| 03 Jun, 2026 | David P Meeker | Director | Acquired A | 35,000 | $0.00 | $0 | 35,000 | Direct |
| 03 Jun, 2026 | Dominick Colangelo | Director | Acquired A | 35,000 | $0.00 | $0 | 35,000 | Direct |
| 19 Feb, 2026 | Thomas Sciascia | Chief Scientific Officer | Acquired A | 85,000 | $0.00 | $0 | 85,000 | Direct |
| 19 Feb, 2026 | Farrell Simon | Chief Commercial Officer | Acquired A | 160,000 | $0.00 | $0 | 160,000 | Direct |
| 19 Feb, 2026 | James V Cassella | Chief Development Officer | Acquired A | 215,000 | $0.00 | $0 | 215,000 | Direct |
| 19 Feb, 2026 | Christopher Galletta | Officer | Acquired A | 35,000 | $0.00 | $0 | 35,000 | Direct |
| 19 Feb, 2026 | Jennifer L Good | President Ceo | Acquired A | 675,000 | $0.00 | $0 | 675,000 | Direct |
| 08 Jan, 2026 | David C Hastings | Chief Financial Officer | Acquired A | 375,000 | $0.00 | $0 | 375,000 | Direct |
| 02 Dec, 2025 | Christopher Galletta | Officer | Acquired M | 4,225 | $0.51 | $2.16K | 26,095 | Direct |