Entrada Therapeutics, Inc. (TRDA) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

40,412,109Shares Outstanding

1,158,495Shares held by institutions

$12,766,615Value of institutional holdings

59.42%Institutional ownership %

3.89%Shares Changed QoQ

107No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

A total of 107 institutions have reported a stake in Entrada Therapeutics, Inc. (NASDAQ:TRDA) as of December 2025, according to recent 13F filings with the SEC.

The collective stake of institutional investors in Entrada Therapeutics moved to 59.4% in December 2025, a shift down from the 70.2% reported for September 2025.
On a quarter-over-quarter basis, institutional holdings shifted by 3.89%, with a year-over-year an increase of 4.90% in the count of filers.
A review of institutional activity for Entrada Therapeutics shows 46 of 107 filers increasing their positions, while 41 reduced their stake, and 20 remained unchanged.
The total number of shares held by institutions in Entrada Therapeutics increased to 24.01Mn as of December 2025, a net change of up by 899.80K shares quarter on quarter, and down 6.58Mn shares year over year.
The top institutional stake in Entrada Therapeutics as of December 31, 2025 belongs to BAKER BROS. ADVISORS LP, which owns 5.07Mn shares, or 12.55% of the company.
Among the most significant buyers of Entrada Therapeutics during December 2025 were TCG Crossover Management, LLC (1.50Mn), BAKER BROS. ADVISORS LP (206.91K), Woodline Partners LP (142.11K), XTX Topco Ltd (117.67K), SPHERA FUNDS MANAGEMENT LTD. (110.94K).
Leading sellers of Entrada Therapeutics stock in December 2025 included RENAISSANCE TECHNOLOGIES LLC (341.67K), MILLENNIUM MANAGEMENT LLC (338.91K), 5AM Venture Management, LLC (200.00K), JANE STREET GROUP, LLC (150.85K), DIMENSIONAL FUND ADVISORS LP (120.90K).
The top 10 institutional holders of Entrada Therapeutics for the quarter ending December 2025 included BAKER BROS. ADVISORS LP (5.07Mn), 5AM Venture Management, LLC (4.06Mn), BlackRock, Inc. (2.15Mn), TCG Crossover Management, LLC (2.09Mn), VANGUARD GROUP INC (1.63Mn), WELLINGTON MANAGEMENT GROUP LLP (1.04Mn), StepStone Group LP (761.28K), GEODE CAPITAL MANAGEMENT, LLC (639.95K), STATE STREET CORP (508.79K), MILLENNIUM MANAGEMENT LLC (497.69K).

107 Institutional Holders

1,158,495 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BAKER BROS. ADVISORS LP	31 Dec, 2025	5,072,730	206,911	4.25%	$52,147,664.00
5AM Venture Management, LLC	31 Dec, 2025	4,056,379	-200,000	-4.70%	$41,699,576.00
BlackRock, Inc.	31 Dec, 2025	2,147,260	103,216	5.05%	$22,073,833.00
TCG Crossover Management, LLC	31 Dec, 2025	2,088,392	1,503,437	257.02%	$21,468,670.00
VANGUARD GROUP INC	31 Dec, 2025	1,632,460	28,235	1.76%	$16,781,689.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	1,044,758	90,339	9.47%	$10,740,113.00
StepStone Group LP	31 Dec, 2025	761,277	0	0.00%	$7,825,928.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	639,947	-5,172	-0.80%	$6,580,002.00
STATE STREET CORP	31 Dec, 2025	508,789	10,174	2.04%	$5,230,351.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	497,695	-338,914	-40.51%	$5,116,305.00
JACOBS LEVY EQUITY MANAGEMENT, INC	31 Dec, 2025	362,786	46,976	14.87%	$3,729,440.00
ACADIAN ASSET MANAGEMENT LLC	31 Dec, 2025	310,833	12,890	4.33%	$3,193.00
CITADEL ADVISORS LLC	31 Dec, 2025	292,770	-42,971	-12.80%	$3,009,676.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	273,378	-120,901	-30.66%	$2,809,666.00
MORGAN STANLEY	31 Dec, 2025	260,251	-86,505	-24.95%	$2,675,384.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	252,635	-341,665	-57.49%	$2,597,088.00
ROYCE & ASSOCIATES LP	31 Dec, 2025	247,147	-98,360	-28.47%	$2,540,671.00
NORTHERN TRUST CORP	31 Dec, 2025	226,301	-27,306	-10.77%	$2,326,375.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	221,269	36,010	19.44%	$2,274,645.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	205,173	-17,163	-7.72%	$2,109,181.00

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