Shattuck Labs, Inc. (STTK) Institutional Ownership

Ownership Summary

According to SEC filings for the period ending December 2025, Shattuck Labs, Inc. (NASDAQ:STTK) is held by 62 institutional firms.

• The collective stake of institutional investors in Shattuck Labs moved to 54.6% in December 2025, a shift up from the 50.6% reported for September 2025.
• In percentage terms, this reflects as a holdings change of 9.50% quarter on quarter, and a decrease of 18.42% year over year.
• During the quarter, 33 institutions bought more Shattuck Labs shares, 12 sold shares, and 17 of the 62 total investors held their position steady.
• This class of investors increased its holdings in Shattuck Labs to 39.18Mn shares for the 13F-cycle ending December 2025, up by 3.40Mn shares quarter on quarter, and up 7.55Mn shares year over year.
• The top institutional stake in Shattuck Labs as of December 31, 2025 belongs to ORBIMED ADVISORS LLC, which owns 6.31Mn shares, or 8.78% of the company.
• Among the most significant buyers of Shattuck Labs during December 2025 were NEXTBio Capital Management LP (3.15Mn), Point72 Asset Management, L.P. (1.07Mn), T. Rowe Price Investment Management, Inc. (506.38K), Aberdeen Group plc (436.67K), FMR LLC (389.23K).
• Leading sellers of Shattuck Labs stock in December 2025 included Prosight Management, LP (3.07Mn), ACADIAN ASSET MANAGEMENT LLC (249.92K), MILLENNIUM MANAGEMENT LLC (213.49K), MARSHALL WACE, LLP (166.74K), 683 Capital Management, LLC (142.22K).
• The top 10 institutional holders of Shattuck Labs for the quarter ending December 2025 included ORBIMED ADVISORS LLC (6.31Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (6.31Mn), Redmile Group, LLC (5.54Mn), NEXTBio Capital Management LP (3.15Mn), Prosight Management, LP (2.38Mn), VANGUARD GROUP INC (2.38Mn), CLARK ESTATES INC/NY (1.48Mn), 683 Capital Management, LLC (1.39Mn), PINNACLE ASSOCIATES LTD (1.35Mn), BANK OF AMERICA CORP /DE/ (1.11Mn).