Shattuck Labs, Inc. (STTK) Institutional Ownership

Institutions by Trading Activity

71,828,571Shares Outstanding

82,177Shares held by institutions

$390,341Value of institutional holdings

0.15%Institutional ownership %

27.54%Shares Changed QoQ

2No. of institutional investors

Recent 13F filings as of December 2025 show that 2 institutional investors hold a position in Shattuck Labs, Inc. (NASDAQ:STTK).

The percentage of Shattuck Labs owned by institutions changed from 50.6% in September 2025 to 0.1% in December 2025, marking a slight down trend.
Institutional share ownership changed by 27.54% QoQ, while the number of institutional owners saw a decrease of 97.37% YoY.
Of these 2 institutional investors, 1 increased their holdings in Shattuck Labs, while 0 of them reduced positions, and 1 investors maintained their exposure.
This class of investors increased its holdings in Shattuck Labs to 104.81K shares for the 13F-cycle ending December 2025, up by 22.63K shares quarter on quarter, and down 31.53Mn shares year over year.
The top institutional stake in Shattuck Labs as of December 31, 2025 belongs to LBJ Family Wealth Advisors, Ltd., which owns 82.18K shares, or 0.11% of the company.
Among the most significant buyers of Shattuck Labs during December 2025 were Mallini Complete Financial Planning LLC (22.63K).
The top 2 institutional holders of Shattuck Labs for the quarter ending December 2025 included LBJ Family Wealth Advisors, Ltd. (82.18K), Mallini Complete Financial Planning LLC (22.63K).

82,177 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
ADAGE CAPITAL PARTNERS GP, L.L.C.	30 Sep, 2025	6,306,127	1,631,127	34.89%	$15,071,644.00
ORBIMED ADVISORS LLC	30 Sep, 2025	6,306,127	6,306,127	0.00%	$15,071,644.00
Redmile Group, LLC	30 Sep, 2025	5,539,724	0	0.00%	$13,239,940.00
Prosight Management, LP	30 Sep, 2025	5,451,195	-1,187,740	-17.89%	$13,028,356.00
VANGUARD GROUP INC	30 Sep, 2025	2,128,401	-19,773	-0.92%	$5,086,878.00
683 Capital Management, LLC	30 Sep, 2025	1,532,216	437,216	39.93%	$3,661,996.00
CLARK ESTATES INC/NY	30 Sep, 2025	1,475,648	0	0.00%	$3,526,799.00
PINNACLE ASSOCIATES LTD	30 Sep, 2025	1,388,723	25,000	1.83%	$3,319,048.00
BANK OF AMERICA CORP /DE/	30 Sep, 2025	1,131,888	1,094,997	2,968.20%	$2,705,212.00
MILLENNIUM MANAGEMENT LLC	30 Sep, 2025	690,901	-152,355	-18.07%	$1,651,253.00
MARSHALL WACE, LLP	30 Sep, 2025	656,653	656,653	0.00%	$1,569,399.00
TAKEDA PHARMACEUTICAL CO LTD	30 Sep, 2025	515,619	0	0.00%	$1,232,329.00
GEODE CAPITAL MANAGEMENT, LLC	30 Sep, 2025	467,959	0	0.00%	$1,118,971.00
BlackRock, Inc.	30 Sep, 2025	411,292	-470,096	-53.34%	$982,988.00
TWO SIGMA INVESTMENTS, LP	30 Sep, 2025	408,598	331,664	431.10%	$976,549.00
ACADIAN ASSET MANAGEMENT LLC	30 Sep, 2025	329,288	68,330	26.18%	$785.00
RENAISSANCE TECHNOLOGIES LLC	30 Sep, 2025	216,867	178,767	469.20%	$518,312.00
STATE STREET CORP	30 Sep, 2025	176,718	0	0.00%	$422,356.00
Pathstone Holdings, LLC	30 Sep, 2025	157,083	-157,083	-50.00%	$375,429.00
TWO SIGMA ADVISERS, LP	30 Sep, 2025	112,677	98,677	704.84%	$269,298.00

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