Summit Therapeutics Inc. (SMMT) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

77,264,333,333Shares Outstanding

2,150,978Shares held by institutions

$33,727,335Value of institutional holdings

0.14%Institutional ownership %

13.21%Shares Changed QoQ

197No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

According to SEC filings for the period ending December 2025, Summit Therapeutics Inc. (NASDAQ:SMMT) is held by 197 institutional firms.

Institutional ownership in Summit Therapeutics edged up to 0.1% in December 2025, compared to 0.1% in September 2025.
Institutional share ownership changed by 13.21% QoQ, while the number of institutional owners saw a decrease of 3.43% YoY.
A review of institutional activity for Summit Therapeutics shows 102 of 197 filers increasing their positions, while 64 reduced their stake, and 31 remained unchanged.
Collectively, institutional investors increased their stake in Summit Therapeutics to 108.71Mn shares as of December 2025, a change that is up by 12.68Mn shares quarter on quarter and up 14.62Mn shares year over year.
BAKER BROS. ADVISORS LP continues to be the largest institutional holder of Summit Therapeutics as of December 31, 2025, with a position of 36.39Mn shares, representing 0.05% of the company's outstanding stock.
Among the most significant buyers of Summit Therapeutics during December 2025 were FMR LLC (4.44Mn), BAKER BROS. ADVISORS LP (2.67Mn), CITADEL ADVISORS LLC (2.27Mn), BlackRock, Inc. (2.00Mn), NORGES BANK (1.37Mn).
Leading sellers of Summit Therapeutics stock in December 2025 included MORGAN STANLEY (1.00Mn), NOMURA HOLDINGS INC (506.69K), UBS Group AG (408.06K), Squarepoint Ops LLC (295.62K), JANE STREET GROUP, LLC (229.90K).
The top 10 institutional holders of Summit Therapeutics for the quarter ending December 2025 included BAKER BROS. ADVISORS LP (36.39Mn), FMR LLC (13.36Mn), VANGUARD GROUP INC (11.18Mn), BlackRock, Inc. (9.36Mn), STATE STREET CORP (6.64Mn), GEODE CAPITAL MANAGEMENT, LLC (3.15Mn), CITADEL ADVISORS LLC (2.48Mn), Polymer Capital Management (HK) LTD (1.42Mn), Pictet Asset Management Holding SA (1.38Mn), NORGES BANK (1.37Mn).

197 Institutional Holders

2,150,978 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BAKER BROS. ADVISORS LP	31 Dec, 2025	36,391,063	2,668,089	7.91%	$636,479,692.00
FMR LLC	31 Dec, 2025	13,360,807	4,442,920	49.82%	$233,680,513.00
VANGUARD GROUP INC	31 Dec, 2025	11,177,220	-202,508	-1.78%	$195,489,577.00
BlackRock, Inc.	31 Dec, 2025	9,361,921	1,998,128	27.13%	$163,739,998.00
STATE STREET CORP	31 Dec, 2025	6,636,361	274,425	4.31%	$116,069,954.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	3,147,480	14,745	0.47%	$55,063,414.00
CITADEL ADVISORS LLC	31 Dec, 2025	2,475,708	2,272,996	1,121.29%	$43,300,133.00
Polymer Capital Management (HK) LTD	31 Dec, 2025	1,421,155	603,879	73.89%	$24,856,001.00
Pictet Asset Management Holding SA	31 Dec, 2025	1,383,775	-220,388	-13.74%	$24,381,751.00
NORGES BANK	31 Dec, 2025	1,373,943	1,373,943	0.00%	$24,030,263.00
APEIRON CAPITAL Ltd	31 Dec, 2025	1,309,241	-1,700	-0.13%	$22,898,625.00
TD ASSET MANAGEMENT INC	31 Dec, 2025	1,205,272	667,742	124.22%	$21,080,207.00
Aberdeen Group plc	31 Dec, 2025	927,171	-212,359	-18.64%	$16,216,221.00
MORGAN STANLEY	31 Dec, 2025	926,579	-1,000,249	-51.91%	$16,205,867.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	892,629	16,239	1.85%	$15,612,081.00
UBS Group AG	31 Dec, 2025	870,719	-408,064	-31.91%	$15,228,875.00
Squarepoint Ops LLC	31 Dec, 2025	715,410	-295,616	-29.24%	$12,512,521.00
Rock Springs Capital Management LP	31 Dec, 2025	710,000	0	0.00%	$12,417,900.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	578,248	553,218	2,210.22%	$10,113,558.00
JANE STREET GROUP, LLC	31 Dec, 2025	554,300	-229,900	-29.32%	$9,694,707.00

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