As of August 29, 2026, the three largest insider holders of SLDB are Advisors Llc Perceptive (Director, 11.83Mn shares), Advisors Llc Perceptive (Director, 11.83Mn shares), Advisors Llc Perceptive (Director, 11.83Mn shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Advisors Llc Perceptive | Director, TenPercentOwner | 0 | 11,833,539 | 11,833,539 | 39.1% | 21 Feb, 2025 |
| 2 | Capital Life Sciences Investors, Llc Bain | TenPercentOwner | 0 | 5,034,582 | 5,034,582 | 16.7% | 21 Feb, 2025 |
| 3 | Capital Management, L.P. Adage | TenPercentOwner | 0 | 4,248,084 | 4,248,084 | 14.1% | 19 Feb, 2025 |
| 4 | Capital Management, L.P. Ra | Director, TenPercentOwner | 0 | 4,192,216 | 4,192,216 | 13.9% | 12 Jan, 2024 |
| 5 | Adam Koppel | Director, TenPercentOwner | 0 | 4,034,582 | 4,034,582 | 13.3% | 12 Jan, 2024 |
| 6 | Alexander Cumbo | President And Ceo | 235,405 | 0 | 235,405 | 0.8% | 18 Feb, 2026 |
| 7 | Ian F Smith | Director | 134,705 | 0 | 134,705 | 0.4% | 02 Apr, 2026 |
| 8 | David T Howton | Chief Operating Officer | 105,077 | 0 | 105,077 | 0.3% | 18 Feb, 2026 |
| 9 | Kevin Tan | Cfo Treasurer | 99,422 | 0 | 99,422 | 0.3% | 18 Feb, 2026 |
| 10 | Gabriel Brooks | Chief Medical Officer | 95,029 | 0 | 95,029 | 0.3% | 18 Feb, 2026 |
| 11 | Jessie Hanrahan | Chief Regulatory Officer | 74,318 | 0 | 74,318 | 0.2% | 18 Feb, 2026 |
| 12 | Paul Herzich | Chief Technology Officer | 72,638 | 0 | 72,638 | 0.2% | 18 Feb, 2026 |
| 13 | Ilan Ganot | Ceo President | 0 | 27,474 | 27,474 | 0.1% | 18 Feb, 2026 |
| 14 | Carl Ashley Morris | Chief Scientific Officer | 19,760 | 0 | 19,760 | 0.1% | 31 Jan, 2023 |
| 15 | Joel Solomon Zev Schneider | Chief Operating Officer | 15,752 | 0 | 15,752 | 0.1% | 15 Mar, 2022 |
| 16 | Jennifer Marlowe | Cso | 6,998 | 0 | 6,998 | 0.0% | 05 Dec, 2023 |
| 17 | Clare Kahn | Director | 2,960 | 0 | 2,960 | 0.0% | 13 Mar, 2025 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 10 Jun, 2026 | Adam Leo Stone | Director | Acquired A | 77,500 | $0.00 | $0 | 77,500 | Direct |
| 10 Jun, 2026 | Advisors Llc Perceptive | Director, TenPercentOwner | Acquired A | 77,500 | $0.00 | $0 | 77,500 | Indirect |
| 10 Jun, 2026 | Lynne Marie Sullivan | Director | Acquired A | 77,500 | $0.00 | $0 | 77,500 | Direct |
| 10 Jun, 2026 | Clare Kahn | Director | Acquired A | 77,500 | $0.00 | $0 | 77,500 | Direct |
| 10 Jun, 2026 | Ian F Smith | Director | Acquired A | 77,500 | $0.00 | $0 | 77,500 | Direct |
| 10 Jun, 2026 | Georgia Keresty | Director | Acquired A | 77,500 | $0.00 | $0 | 77,500 | Direct |
| 10 Jun, 2026 | Ilan Ganot | Director | Acquired A | 77,500 | $0.00 | $0 | 77,500 | Direct |
| 10 Jun, 2026 | Sukumar Nagendran | Director | Acquired A | 77,500 | $0.00 | $0 | 77,500 | Direct |
| 02 Apr, 2026 | Ian F Smith | Director | Acquired M | 3,441 | — | — | 134,705 | Direct |
| 02 Apr, 2026 | Ian F Smith | Director | Disposed M | 3,441 | $0.00 | $0 | 10,320 | Direct |
| 09 Mar, 2026 | Advisors Llc Perceptive | Director, TenPercentOwner | Acquired A | 8,912,655 | $5.61 | $49.99Mn | 8,912,655 | Indirect |
| 09 Mar, 2026 | Advisors Llc Perceptive | Director, TenPercentOwner | Acquired A | 8,912,655 | $5.61 | $49.99Mn | 8,912,655 | Indirect |
| 09 Mar, 2026 | Advisors Llc Perceptive | Director, TenPercentOwner | Acquired A | 8,912,655 | $5.61 | $49.99Mn | 8,912,655 | Indirect |
| 13 Feb, 2026 | Paul Herzich | Chief Technology Officer | Acquired M | 7,187 | — | — | 76,254 | Direct |
| 13 Feb, 2026 | Ilan Ganot | Director | Acquired M | 4,861 | — | — | 30,132 | Indirect |
| 13 Feb, 2026 | Kevin Tan | Cfo Treasurer | Acquired M | 10,625 | — | — | 104,826 | Direct |
| 13 Feb, 2026 | Gabriel Brooks | Chief Medical Officer | Acquired M | 10,937 | — | — | 95,029 | Direct |
| 13 Feb, 2026 | Alexander Cumbo | President And Ceo | Acquired M | 30,031 | — | — | 252,049 | Direct |
| 13 Feb, 2026 | Jessie Hanrahan | Chief Regulatory Officer | Acquired M | 8,125 | — | — | 78,452 | Direct |
| 13 Feb, 2026 | David T Howton | Chief Operating Officer | Acquired M | 14,687 | — | — | 112,546 | Direct |