Rezolute, Inc. (RZLT) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

103,518,182Shares Outstanding

3,782,910Shares held by institutions

$13,731,963Value of institutional holdings

87.27%Institutional ownership %

42.63%Shares Changed QoQ

116No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Rezolute, Inc. (NASDAQ:RZLT) includes 116 filers as of the latest reporting cycle ending December 2025.

Rezolute saw its institutional ownership percentage fell to 87.3% in December 2025 from 105.3% in September 2025.
In percentage terms, this reflects as a holdings change of 42.63% quarter on quarter, and an increase of 63.38% year over year.
The latest 13F cycle for Rezolute reveals that of 116 total investors, 81 funds grew their exposure, whereas 24 reduced theirs and 11 made no changes.
Collectively, institutional investors increased their stake in Rezolute to 90.34Mn shares as of December 2025, a change that is up by 27.00Mn shares quarter on quarter and up 46.94Mn shares year over year.
With 16.53Mn shares, FEDERATED HERMES, INC. commands the largest institutional position in Rezolute as of December 31, 2025, equating to 15.97% of the company.
Among the most significant buyers of Rezolute during December 2025 were RA CAPITAL MANAGEMENT, L.P. (9.18Mn), Opaleye Management Inc. (5.38Mn), BANK OF AMERICA CORP /DE/ (3.04Mn), BALYASNY ASSET MANAGEMENT L.P. (2.68Mn), FEDERATED HERMES, INC. (2.50Mn).
Leading sellers of Rezolute stock in December 2025 included FMR LLC (10.46Mn), GREAT POINT PARTNERS LLC (1.50Mn), ADAR1 Capital Management, LLC (777.30K), Woodline Partners LP (570.68K), PFM Health Sciences, LP (246.47K).
The top 10 institutional holders of Rezolute for the quarter ending December 2025 included FEDERATED HERMES, INC. (16.53Mn), RA CAPITAL MANAGEMENT, L.P. (9.18Mn), BlackRock, Inc. (6.77Mn), Opaleye Management Inc. (6.29Mn), VANGUARD GROUP INC (4.79Mn), BALYASNY ASSET MANAGEMENT L.P. (4.51Mn), BANK OF AMERICA CORP /DE/ (4.33Mn), STATE STREET CORP (3.98Mn), UBS Group AG (2.82Mn), Affinity Asset Advisors, LLC (2.35Mn).

116 Institutional Holders

3,782,910 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
FEDERATED HERMES, INC.	31 Dec, 2025	16,534,712	2,500,000	17.81%	$39,021,920.00
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	9,180,000	9,180,000	0.00%	$21,664,800.00
BlackRock, Inc.	31 Dec, 2025	6,768,206	1,763,770	35.24%	$15,972,966.00
Opaleye Management Inc.	31 Dec, 2025	6,287,156	5,383,714	595.91%	$14,837,688.00
VANGUARD GROUP INC	31 Dec, 2025	4,788,511	378,429	8.58%	$11,300,886.00
BALYASNY ASSET MANAGEMENT L.P.	31 Dec, 2025	4,506,861	2,684,133	147.26%	$10,636,192.00
BANK OF AMERICA CORP /DE/	31 Dec, 2025	4,325,248	3,040,286	236.61%	$10,207,585.00
STATE STREET CORP	31 Dec, 2025	3,981,708	1,890,232	90.38%	$9,396,831.00
UBS Group AG	31 Dec, 2025	2,816,291	120,313	4.46%	$6,646,447.00
Affinity Asset Advisors, LLC	31 Dec, 2025	2,351,144	251,144	11.96%	$5,548,700.00
FMR LLC	31 Dec, 2025	2,305,568	-10,458,665	-81.94%	$5,441,140.00
Integral Health Asset Management, LLC	31 Dec, 2025	2,000,000	0	0.00%	$4,720,000.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,954,733	107,349	5.81%	$4,614,157.00
BARCLAYS PLC	31 Dec, 2025	1,911,066	1,601,370	517.08%	$4,510,115.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	1,711,194	1,531,922	854.52%	$4,038,418.00
Vestal Point Capital, LP	31 Dec, 2025	1,686,000	1,686,000	0.00%	$3,978,960.00
MORGAN STANLEY	31 Dec, 2025	1,516,435	1,178,515	348.76%	$3,578,786.00
JANE STREET GROUP, LLC	31 Dec, 2025	1,423,399	1,282,086	907.27%	$3,359,222.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	1,329,782	788,295	145.58%	$3,138,286.00
AMERIPRISE FINANCIAL INC	31 Dec, 2025	1,093,925	842,296	334.74%	$2,581,663.00

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