Rezolute, Inc. (RZLT) Institutional Ownership

Ownership Summary

Rezolute, Inc. (NASDAQ:RZLT) showed up in the 13F filings of 119 institutional investors as of December 2025.

• These investors held 87.3% of outstanding shares in December 2025, up from 85.5% in September 2025.
• They increased total shares held in Rezolute by 40.39% from the prior quarter, while the number of investors in RZLT increased 67.61% year over year.
• Of these 119 holders, 82 added to their stakes in Rezolute, 25 trimmed positions, and 12 made no changes.
• In total, institutional investors held 90.56Mn shares in Rezolute as of December 2025, up by 26.05Mn shares quarter on quarter, and up 47.29Mn shares year over year.
• Federated Hermes, Inc. is the top holder of Rezolute as of December 31, 2025, with 16.53Mn shares representing 15.95% of outstanding stock.
• The most significant purchases of RZLT for the quarter ending December 2025 came from RA CAPITAL MANAGEMENT, L.P. (9.18Mn), Opaleye Management Inc. (5.38Mn), BALYASNY ASSET MANAGEMENT L.P. (2.68Mn), Federated Hermes, Inc. (2.5Mn), State Street Corp (1.89Mn).
• Leading sellers of Rezolute shares for the quarter ending December 2025 were FMR LLC (10.46Mn), GREAT POINT PARTNERS LLC (1.5Mn), ADAR1 Capital Management, LLC (738.62K), Woodline Partners LP (570.68K), Invesco Ltd. (314.52K).
• According to Business Quant data, leading holders of RZLT for December 2025 are Federated Hermes, Inc. (16.53Mn), RA CAPITAL MANAGEMENT, L.P. (9.18Mn), BlackRock, Inc. (6.77Mn), Opaleye Management Inc. (6.29Mn), VANGUARD GROUP INC (4.79Mn), BALYASNY ASSET MANAGEMENT L.P. (4.51Mn), Bank Of America Corp /De/ (4.33Mn), State Street Corp (3.98Mn), UBS Group AG (2.82Mn), Affinity Asset Advisors, LLC (2.35Mn).