RPRX's three largest insider shareholders as of June 18, 2026 are 1978 Sicaf Sif S.A. Gg (TenPercentOwner, 22.08Mn shares), 1978 Sicaf Sif S.A. - Gg Strategic Gg (TenPercentOwner, 21.43Mn shares), Mario Germano Giuliani (Director, 7.80Mn shares).
| Holder | Position | Shares (Direct) | Shares (Indirect) | Report Date |
|---|---|---|---|---|
| Rory B Riggs | - | 320,099 | 0 | 22 Feb, 2024 |
| Elizabeth H Weatherman | - | 8,558 | 0 | 31 Jul, 2025 |
| Ted W Love | - | 53,848 | 0 | 14 May, 2025 |
| David C Hodgson | - | 33,328 | 0 | 14 May, 2025 |
| Errol B Desouza | - | 81,352 | 0 | 14 May, 2025 |
| Gregory Norden | - | 194,848 | 0 | 11 Aug, 2025 |
| Henry A Fernandez | - | 65,324 | 0 | 30 Jun, 2025 |
| Pablo G. Legorreta | Ceo, Chairman Of The Board | 1,098,783 | 0 | 13 Feb, 2026 |
| Bonnie L Bassler | - | 73,947 | 0 | 31 Mar, 2026 |
| Vlad Coric | - | 10,798 | 0 | 14 May, 2025 |
| Carole Ho | - | 8,558 | 0 | 31 Jul, 2025 |
| Catherine M. Engelbert | - | 51,128 | 0 | 15 May, 2025 |
| Christopher Hite | Evp Vice Chairman | 0 | 685,136 | 13 Feb, 2026 |
| James F. Reddoch | Evp Chief Scientific Officer | 0 | 820,800 | 30 Sep, 2022 |
| Terrance P. Coyne | Evp Cfo | 0 | 74,927 | 02 Apr, 2026 |
| Mario Germano Giuliani | - | 0 | 7,795,072 | 07 Dec, 2022 |
| 1978 Sicaf Sif S.A. - Gg Strategic Gg | - | 0 | 21,426,170 | 22 Sep, 2022 |
| 1978 Sicaf Sif S.A. Gg | - | 0 | 22,081,156 | 16 Sep, 2022 |
| George W. Lloyd | Evp, Investments Gc | 0 | 495,860 | 18 Nov, 2021 |
| Management Ltd Avara | - | 0 | 2,477,520 | 03 Jan, 2024 |
| Marshall Urist | Evp, Research Investments | 27,368 | 0 | 13 Feb, 2026 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 01 Apr, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 1,875 | $48.33 | 42,011 | I | S |
| 01 Apr, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 32,916 | $48.33 | 32,916 | I | S |
| 31 Mar, 2026 | Bonnie L Bassler | Class A Ordinary Shares | A | 815 | $45.98 | 73,947 | D | A |
| 23 Mar, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 32,916 | $45.53 | 65,832 | I | S |
| 23 Mar, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 1,875 | $45.53 | 43,886 | I | S |
| 02 Mar, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 22,487 | $46.67 | 109,177 | I | S |
| 02 Mar, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 10,429 | $47.01 | 98,748 | I | S |
| 02 Mar, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 1,292 | $46.67 | 46,344 | I | S |
| 02 Mar, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 583 | $47.01 | 45,761 | I | S |
| 23 Feb, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 32,916 | $45.32 | 131,664 | I | S |
| 23 Feb, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 1,875 | $45.32 | 47,636 | I | S |
| 11 Feb, 2026 | Terrance P. Coyne | Class A Ordinary Shares | A | 26,626 | $0.00 | 49,511 | I | A |
| 11 Feb, 2026 | Marshall Urist | Class A Ordinary Shares | A | 19,970 | $0.00 | 27,368 | D | A |
| 11 Feb, 2026 | Christopher Hite | Class A Ordinary Shares | A | 26,626 | $0.00 | 685,136 | I | A |
| 11 Feb, 2026 | Marshall Urist | Class A Ordinary Shares | A | 19,970 | $0.00 | 27,368 | D | A |
| 11 Feb, 2026 | Pablo G. Legorreta | Class A Ordinary Shares | A | 157,828 | $0.00 | 1,098,783 | D | A |
| 02 Feb, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 102,581 | $42.08 | 292,415 | I | S |
| 03 Feb, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 108,759 | $42.84 | 183,656 | I | S |
| 04 Feb, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 19,076 | $43.29 | 164,580 | I | S |
| 02 Feb, 2026 | Terrance P. Coyne | Class A Ordinary Shares | D | 5,843 | $42.08 | 30,167 | I | S |