Repligen Corp (RGEN) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

57,350,000Shares Outstanding

632,720Shares held by institutions

$85,676,615Value of institutional holdings

97.50%Institutional ownership %

4.98%Shares Changed QoQ

447No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Recent 13F filings as of December 2025 show that 447 institutional investors hold a position in Repligen Corp (NASDAQ:RGEN).

Institutional ownership in Repligen edged down to 97.5% in December 2025, compared to 106.0% in September 2025.
In percentage terms, this reflects as a holdings change of 4.98% quarter on quarter, and an increase of 4.68% year over year.
A review of institutional activity for Repligen shows 230 of 447 filers increasing their positions, while 139 reduced their stake, and 78 remained unchanged.
This class of investors increased its holdings in Repligen to 55.92Mn shares for the 13F-cycle ending December 2025, up by 2.65Mn shares quarter on quarter, and down 1.03Mn shares year over year.
With 6.62Mn shares, BlackRock, Inc. commands the largest institutional position in Repligen as of December 31, 2025, equating to 11.54% of the company.
Among the most significant buyers of Repligen during December 2025 were MASSACHUSETTS FINANCIAL SERVICES CO /MA/ (1.22Mn), RTW INVESTMENTS, LP (1.06Mn), FRANKLIN RESOURCES INC (677.15K), FRED ALGER MANAGEMENT, LLC (553.11K), CONGRESS ASSET MANAGEMENT CO (527.71K).
Leading sellers of Repligen stock in December 2025 included BALYASNY ASSET MANAGEMENT L.P. (652.19K), T. Rowe Price Investment Management, Inc. (528.69K), Point72 Asset Management, L.P. (434.41K), Holocene Advisors, LP (416.06K), BROWN CAPITAL MANAGEMENT LLC (394.89K).
The top 10 institutional holders of Repligen for the quarter ending December 2025 included BlackRock, Inc. (6.62Mn), VANGUARD GROUP INC (4.99Mn), FMR LLC (2.87Mn), UNITED CAPITAL FINANCIAL ADVISORS, LLC (2.77Mn), STATE STREET CORP (1.72Mn), CITADEL ADVISORS LLC (1.39Mn), Bank of New York Mellon Corp (1.34Mn), MASSACHUSETTS FINANCIAL SERVICES CO /MA/ (1.22Mn), FRANKLIN RESOURCES INC (1.10Mn), RTW INVESTMENTS, LP (1.06Mn).

447 Institutional Holders

632,720 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	6,619,271	479,541	7.81%	$1,084,633,737.00
VANGUARD GROUP INC	31 Dec, 2025	4,993,945	-50,246	-1.00%	$818,307,828.00
FMR LLC	31 Dec, 2025	2,867,846	176,634	6.56%	$469,925,204.00
UNITED CAPITAL FINANCIAL ADVISORS, LLC	31 Dec, 2025	2,770,862	14,919	0.54%	$454,033,447.00
STATE STREET CORP	31 Dec, 2025	1,719,093	-82,443	-4.58%	$281,690,579.00
CITADEL ADVISORS LLC	31 Dec, 2025	1,394,252	-290,468	-17.24%	$228,462,133.00
Bank of New York Mellon Corp	31 Dec, 2025	1,344,706	28,870	2.19%	$220,343,507.00
MASSACHUSETTS FINANCIAL SERVICES CO /MA/	31 Dec, 2025	1,215,527	1,215,527	0.00%	$199,176,255.00
FRANKLIN RESOURCES INC	31 Dec, 2025	1,101,447	677,146	159.59%	$180,483,177.00
RTW INVESTMENTS, LP	31 Dec, 2025	1,064,000	1,064,000	0.00%	$174,347,040.00
Conestoga Capital Advisors, LLC	31 Dec, 2025	1,057,975	101,062	10.56%	$173,359,783.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,029,817	-2,622	-0.25%	$168,778,619.00
Point72 Asset Management, L.P.	31 Dec, 2025	1,006,310	-434,411	-30.15%	$164,893,957.00
Champlain Investment Partners, LLC	31 Dec, 2025	1,003,951	-335,295	-25.04%	$164,507,411.00
ALLIANCEBERNSTEIN L.P.	31 Dec, 2025	994,869	-109,302	-9.90%	$163,019,234.00
Holocene Advisors, LP	31 Dec, 2025	961,040	-416,064	-30.21%	$157,476,014.00
FRED ALGER MANAGEMENT, LLC	31 Dec, 2025	911,527	553,105	154.32%	$149,362,814.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	804,410	4,900	0.61%	$131,820,884.00
CONGRESS ASSET MANAGEMENT CO	31 Dec, 2025	746,306	527,714	241.42%	$122,289,701.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	660,646	-231,510	-25.95%	$108,253,454.00

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