uniQure N.V. (QURE) Institutional Ownership

Ownership Summary

A total of 218 institutions have reported a stake in uniQure N.V. (NASDAQ:QURE) as of December 2025, according to recent 13F filings with the SEC.

• uniQure saw its institutional ownership percentage rose to 120.0% in December 2025 from 109.8% in September 2025.
• In percentage terms, this reflects as a holdings change of 29.60% quarter on quarter, and an increase of 56.83% year over year.
• Among the 218 institutional holders of uniQure, 138 added to their stakes while 61 trimmed their positions and 19 held steady.
• The aggregate institutional position in uniQure now stands at 64.30Mn shares as of December 2025, after investors increased their holdings (up by 14.69Mn shares quarter on quarter which is up 21.87Mn shares year over year).
• The top institutional stake in uniQure as of December 31, 2025 belongs to FMR LLC, which owns 6.24Mn shares, or 11.65% of the company.
• Among the most significant buyers of uniQure during December 2025 were STATE STREET CORP (1.79Mn), JPMORGAN CHASE & CO (1.79Mn), Avoro Capital Advisors LLC (1.71Mn), MPM BioImpact LLC (1.38Mn), Tyro Capital Management LLC (1.33Mn).
• Leading sellers of uniQure stock in December 2025 included FRANKLIN RESOURCES INC (1.24Mn), FRED ALGER MANAGEMENT, LLC (945.51K), Eversept Partners, LP (814.55K), JANE STREET GROUP, LLC (752.90K), RTW INVESTMENTS, LP (713.51K).
• The top 10 institutional holders of uniQure for the quarter ending December 2025 included FMR LLC (6.24Mn), Avoro Capital Advisors LLC (6.15Mn), RTW INVESTMENTS, LP (3.71Mn), Aberdeen Group plc (3.68Mn), STATE STREET CORP (3.23Mn), JPMORGAN CHASE & CO (2.93Mn), BlackRock, Inc. (1.97Mn), TWO SIGMA INVESTMENTS, LP (1.45Mn), MPM BioImpact LLC (1.38Mn), JENNISON ASSOCIATES LLC (1.37Mn).