uniQure N.V. (QURE) Institutional Ownership

Institutions by Trading Activity

62,742,847Shares Outstanding

59,606,198Shares held by institutions

$2,898,053,283Value of institutional holdings

95.00%Institutional ownership %

-1.03%Shares Changed QoQ

210No. of institutional investors

uniQure N.V. (NASDAQ:QURE) showed up in the 13F filings of 210 institutional investors as of March 2026.

These investors collectively held 95.0% of uniQure's outstanding shares in March 2026, down from 121.1% in December 2025.
Their total shares held in QURE decreased -1.03% quarter over quarter, and separately, investors owning uniQure increased 48.94% from a year ago.
Of these 210 funds, 120 grew their exposure to uniQure, 61 cut back, and 29 maintained positions.
The aggregate institutional position in uniQure amounted to 59.61Mn shares as of March 2026, down by 617.76K shares quarter on quarter, and up 6.52Mn shares year over year.
Avoro Capital Advisors LLC holds the largest position in QURE at 5.96Mn shares as of March 31, 2026, or 9.5% of shares outstanding.
Leading buyers of uniQure shares for the quarter ending March 2026 were Aberdeen Group plc (1.63Mn), ORBIMED ADVISORS LLC (1.4Mn), Two Seas Capital LP (1.3Mn), TWO SIGMA INVESTMENTS, LP (1.22Mn), Siren, L.L.C. (1.0Mn).
Leading sellers of uniQure shares for the quarter ending March 2026 were Avoro Capital Advisors LLC (6.34Mn), FMR LLC (4.5Mn), RTW INVESTMENTS, LP (1.13Mn), Goldman Sachs Group Inc (1.07Mn), State Street Corp (970.53K).
Per Business Quant data, the top 10 holders of uniQure for the quarter ending March 2026 are Avoro Capital Advisors LLC (5.96Mn), Aberdeen Group plc (5.31Mn), Jpmorgan Chase & Co (2.84Mn), TWO SIGMA INVESTMENTS, LP (2.68Mn), RTW INVESTMENTS, LP (2.59Mn), State Street Corp (2.26Mn), ORBIMED ADVISORS LLC (2.14Mn), FMR LLC (1.74Mn), BlackRock, Inc. (1.73Mn), MPM BioImpact LLC (1.37Mn).

59,606,198 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Avoro Capital Advisors LLC	31 Mar, 2026	5,959,595	-6,340,405	-51.55%	$97,439,378.00
Aberdeen Group plc	31 Mar, 2026	5,306,386	1,627,746	44.25%	$86,759,411.00
Jpmorgan Chase & Co	31 Mar, 2026	2,837,466	-97,160	-3.31%	$41,795,881.00
TWO SIGMA INVESTMENTS, LP	31 Mar, 2026	2,675,871	1,224,587	84.38%	$43,750,491.00
RTW INVESTMENTS, LP	31 Mar, 2026	2,586,356	-1,125,106	-30.31%	$42,286,921.00
State Street Corp	31 Mar, 2026	2,260,512	-970,531	-30.04%	$36,959,371.00
ORBIMED ADVISORS LLC	31 Mar, 2026	2,136,149	1,398,749	189.69%	$34,926,036.00
FMR LLC	31 Mar, 2026	1,743,808	-4,497,128	-72.06%	$28,511,258.00
BlackRock, Inc.	31 Mar, 2026	1,733,458	-241,530	-12.23%	$28,342,039.00
MPM BioImpact LLC	31 Mar, 2026	1,369,231	-12,397	-0.90%	$22,386,927.00
Two Seas Capital LP	31 Mar, 2026	1,300,000	1,300,000	0.00%	$21,255,000.00
Goldman Sachs Group Inc	31 Mar, 2026	1,263,236	-1,071,980	-45.90%	$20,653,909.00
JENNISON ASSOCIATES LLC	31 Mar, 2026	1,233,789	-137,401	-10.02%	$20,172,451.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Mar, 2026	1,002,800	-215,550	-17.69%	$16,395,780.00
Siren, L.L.C.	31 Mar, 2026	1,000,000	1,000,000	0.00%	$16,350,000.00
BALYASNY ASSET MANAGEMENT L.P.	31 Mar, 2026	964,290	828,646	610.90%	$15,766,142.00
Integral Health Asset Management, LLC	31 Mar, 2026	900,000	0	0.00%	$14,715,000.00
Fiera Capital Corp	31 Mar, 2026	816,893	48,383	6.30%	$13,356,201.00
GEODE CAPITAL MANAGEMENT, LLC	31 Mar, 2026	804,610	28,539	3.68%	$13,160,562.00
MILLENNIUM MANAGEMENT LLC	31 Mar, 2026	792,756	-10,849	-1.35%	$12,961,561.00

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