Q32 Bio Inc. (QTTB) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

6,463,183Shares held by institutions

$37,809,621Value of institutional holdings

73.52%Institutional ownership %

-11.39%Shares Changed QoQ

59No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Q32 Bio Inc. (NASDAQ:QTTB) has 51 institutional investors with active 13F positions as of December 2025.

They owned 65.9% of outstanding stock in December 2025, down from 68.9% the prior quarter.
They decreased total shares held in Q32 Bio by -2.48% from the prior quarter, while the number of investors in QTTB decreased 44.57% year over year.
During the quarter, 16 of these 51 funds increased positions in QTTB, 20 reduced exposure, and 15 held steady.
Altogether, these fund groups held 8.06Mn shares in QTTB by December 2025, down by 205.38K shares quarter on quarter, and down 4.77Mn shares year over year.
ORBIMED ADVISORS LLC leads ownership in QTTB with 2.25Mn shares as of December 31, 2025, equal to 18.41% of outstanding shares.
The most significant purchases of QTTB for the quarter ending December 2025 came from Opaleye Management Inc. (213.36K), RENAISSANCE TECHNOLOGIES LLC (52.3K), ADAR1 Capital Management, LLC (40.0K), CITADEL ADVISORS LLC (35.61K), VANGUARD GROUP INC (25.64K).
The largest sellers of Q32 Bio for the quarter ending December 2025 were ACORN CAPITAL ADVISORS, LLC (310.0K), Monaco Asset Management SAM (260.22K), MILLENNIUM MANAGEMENT LLC (53.5K), BlackRock, Inc. (33.07K), FMR LLC (12.5K).
Q32 Bio's 10 largest shareholders as of December 2025 include ORBIMED ADVISORS LLC (2.25Mn), Atlas Venture Life Science Advisors, LLC (2.09Mn), Carlyle Group Inc. (1.1Mn), ACORN CAPITAL ADVISORS, LLC (493.42K), VANGUARD GROUP INC (321.05K), ARCH Venture Management, LLC (320.48K), Pfizer Inc (277.78K), Sanofi (244.08K), Opaleye Management Inc. (213.36K), GEODE CAPITAL MANAGEMENT, LLC (106.11K) per Business Quant data.

51 Institutional Holders

6,463,183 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	-33,073	-35.56%	$0.00
ORBIMED ADVISORS LLC	31 Dec, 2025	0	0.00%	$0.00
Atlas Venture Life Science Advisors, LLC	31 Dec, 2025	0	0.00%	$0.00
Rockefeller Capital Management L.P.	31 Dec, 2025	577	100.00%	$0.00
Carlyle Group Inc.	31 Dec, 2025	0	0.00%	$0.00
ACORN CAPITAL ADVISORS, LLC	31 Dec, 2025	-310,000	-38.58%	$0.00
Barclays Plc	31 Dec, 2025	-11,246	-99.83%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	25,642	8.68%	$0.00
Monaco Asset Management SAM	31 Dec, 2025	-260,218	-83.63%	$0.00
ARCH Venture Management, LLC	31 Dec, 2025	0	0.00%	$0.00
ADAR1 Capital Management, LLC	31 Dec, 2025	40,000	0.00%	$0.00
Pfizer Inc	31 Dec, 2025	0	0.00%	$0.00
Affinity Asset Advisors, LLC	31 Dec, 2025	0	0.00%	$0.00
Sanofi	31 Dec, 2025	0	0.00%	$0.00
XTX Topco Ltd	31 Dec, 2025	20,353	0.00%	$0.00
Opaleye Management Inc.	31 Dec, 2025	213,363	0.00%	$0.00
Scientech Research LLC	31 Dec, 2025	15,510	0.00%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	17,617	19.91%	$0.00
UBS Group AG	31 Dec, 2025	8,360	159.36%	$0.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	52,300	110.57%	$0.00

1 - 20 of 51

Research Tools