Pliant Therapeutics, Inc. (PLRX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

61,165,116Shares Outstanding

4,317,740Shares held by institutions

$4,879,046Value of institutional holdings

75.70%Institutional ownership %

-4.74%Shares Changed QoQ

94No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Pliant Therapeutics, Inc. (NASDAQ:PLRX) includes 94 filers as of the latest reporting cycle ending December 2025.

The percentage of Pliant Therapeutics owned by institutions changed from 81.6% in September 2025 to 75.7% in December 2025, marking a slight down trend.
In percentage terms, this reflects as a holdings change of -4.74% quarter on quarter, and a decrease of 40.88% year over year.
Among the 94 institutional holders of Pliant Therapeutics, 42 added to their stakes while 33 trimmed their positions and 19 held steady.
This class of investors decreased its holdings in Pliant Therapeutics to 46.30Mn shares for the 13F-cycle ending December 2025, down by 2.30Mn shares quarter on quarter, and down 18.85Mn shares year over year.
As of December 31, 2025, TANG CAPITAL MANAGEMENT LLC held Pliant Therapeutics's largest shareholding position with over 6.14Mn shares, representing 10.04% of total outstanding shares.
Among the most significant buyers of Pliant Therapeutics during December 2025 were BML Capital Management, LLC (1.55Mn), Prosight Management, LP (1.54Mn), Monaco Asset Management SAM (1.12Mn), Centiva Capital, LP (1.00Mn), MARSHALL WACE, LLP (780.67K).
Leading sellers of Pliant Therapeutics stock in December 2025 included Point72 Asset Management, L.P. (4.29Mn), MORGAN STANLEY (2.96Mn), Woodline Partners LP (2.48Mn), JPMORGAN CHASE & CO (917.61K), BARCLAYS PLC (358.97K).
The top 10 institutional holders of Pliant Therapeutics for the quarter ending December 2025 included TANG CAPITAL MANAGEMENT LLC (6.14Mn), Blue Owl Capital Holdings LP (2.97Mn), VANGUARD GROUP INC (2.82Mn), CITADEL ADVISORS LLC (2.58Mn), ACADIAN ASSET MANAGEMENT LLC (2.36Mn), Woodline Partners LP (2.03Mn), Monaco Asset Management SAM (1.94Mn), Redmile Group, LLC (1.62Mn), Prosight Management, LP (1.56Mn), BML Capital Management, LLC (1.55Mn).

94 Institutional Holders

4,317,740 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
TANG CAPITAL MANAGEMENT LLC	31 Dec, 2025	6,143,132	139,686	2.33%	$7,494,621.00
Blue Owl Capital Holdings LP	31 Dec, 2025	2,969,199	0	0.00%	$3,622,423.00
VANGUARD GROUP INC	31 Dec, 2025	2,818,241	42,303	1.52%	$3,438,255.00
CITADEL ADVISORS LLC	31 Dec, 2025	2,583,332	243,864	10.42%	$3,151,665.00
ACADIAN ASSET MANAGEMENT LLC	31 Dec, 2025	2,364,669	-4,873	-0.21%	$2,879.00
Woodline Partners LP	31 Dec, 2025	2,026,191	-2,478,626	-55.02%	$2,471,953.00
Monaco Asset Management SAM	31 Dec, 2025	1,938,747	1,116,054	135.66%	$2,365,271.00
Redmile Group, LLC	31 Dec, 2025	1,616,228	24,533	1.54%	$1,971,798.00
Prosight Management, LP	31 Dec, 2025	1,555,744	1,535,257	7,493.81%	$1,898,008.00
BML Capital Management, LLC	31 Dec, 2025	1,546,137	1,546,137	0.00%	$1,886,287.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	1,245,600	173,100	16.14%	$1,519,632.00
JPMORGAN CHASE & CO	31 Dec, 2025	1,212,875	-917,614	-43.07%	$1,479,707.00
MARSHALL WACE, LLP	31 Dec, 2025	1,080,128	780,667	260.69%	$1,317,756.00
BlackRock, Inc.	31 Dec, 2025	1,073,272	-347,591	-24.46%	$1,309,392.00
UBS Group AG	31 Dec, 2025	1,062,615	-259,402	-19.62%	$1,296,390.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	1,045,818	34,016	3.36%	$1,275,898.00
Centiva Capital, LP	31 Dec, 2025	1,000,000	1,000,000	0.00%	$1,220,000.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	953,293	170,038	21.71%	$1,163,017.00
Peapod Lane Capital LLC	31 Dec, 2025	886,374	-210,654	-19.20%	$1,081,376.00
Eversept Partners, LP	31 Dec, 2025	842,023	17,429	2.11%	$1,027,268.00

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