Pliant Therapeutics, Inc. (PLRX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

61,406,475Shares Outstanding

50,546,077Shares held by institutions

$66,215,361Value of institutional holdings

82.31%Institutional ownership %

-3.49%Shares Changed QoQ

97No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Pliant Therapeutics, Inc. (NASDAQ:PLRX) is held by 97 institutional investors per 13F filings through December 2025.

Collectively, these holders controlled 81.4% of Pliant Therapeutics's outstanding shares in December 2025, down from 86.0% in September 2025.
They decreased total shares held in PLRX by -3.08% quarter over quarter, and investors in Pliant Therapeutics decreased 38.99% from a year ago.
During the quarter, 44 of these 97 funds increased positions in PLRX, 36 reduced exposure, and 17 held steady.
Institutional investors collectively held 49.99Mn shares in Pliant Therapeutics as of December 2025, down by 1.59Mn shares quarter on quarter, and down 18.17Mn shares year over year.
TANG CAPITAL MANAGEMENT LLC is the top holder of Pliant Therapeutics as of December 31, 2025, with 6.14Mn shares representing 10.0% of outstanding stock.
The largest buyers of Pliant Therapeutics for the quarter ending December 2025 were Blue Owl Capital Holdings LP (2.97Mn), BML Capital Management, LLC (1.55Mn), Prosight Management, LP (1.54Mn), Monaco Asset Management SAM (1.12Mn), Centiva Capital, LP (1.0Mn).
The biggest sellers of Pliant Therapeutics for the quarter ending December 2025 included Point72 Asset Management, L.P. (4.29Mn), Jpmorgan Chase & Co (3.05Mn), Morgan Stanley (2.96Mn), Woodline Partners LP (2.48Mn), Barclays Plc (1.15Mn).
Business Quant data shows the 10 biggest positions in Pliant Therapeutics as of December 2025 are held by TANG CAPITAL MANAGEMENT LLC (6.14Mn), Blue Owl Capital Holdings LP (5.94Mn), VANGUARD GROUP INC (2.82Mn), CITADEL ADVISORS LLC (2.58Mn), ACADIAN ASSET MANAGEMENT LLC (2.36Mn), Woodline Partners LP (2.03Mn), Monaco Asset Management SAM (1.94Mn), Redmile Group, LLC (1.62Mn), Prosight Management, LP (1.56Mn), BML Capital Management, LLC (1.55Mn).

97 Institutional Holders

50,546,077 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
TANG CAPITAL MANAGEMENT LLC	31 Dec, 2025	6,143,132	139,686	2.33%	$7,494,621.00
Blue Owl Capital Holdings LP	31 Dec, 2025	5,938,398	2,969,199	100.00%	$7,244,846.00
VANGUARD GROUP INC	31 Dec, 2025	2,818,241	42,303	1.52%	$3,438,255.00
CITADEL ADVISORS LLC	31 Dec, 2025	2,583,332	243,864	10.42%	$3,151,665.00
ACADIAN ASSET MANAGEMENT LLC	31 Dec, 2025	2,364,669	-4,873	-0.21%	$2,879.00
Woodline Partners LP	31 Dec, 2025	2,026,191	-2,478,626	-55.02%	$2,471,953.00
Monaco Asset Management SAM	31 Dec, 2025	1,938,747	1,116,054	135.66%	$2,365,271.00
Redmile Group, LLC	31 Dec, 2025	1,616,228	24,533	1.54%	$1,971,798.00
Prosight Management, LP	31 Dec, 2025	1,555,744	1,535,257	7,493.81%	$1,898,008.00
BML Capital Management, LLC	31 Dec, 2025	1,546,137	1,546,137	0.00%	$1,886,287.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	1,245,600	173,100	16.14%	$1,519,632.00
Jpmorgan Chase & Co	31 Dec, 2025	1,212,875	-3,048,103	-71.54%	$1,479,707.00
MARSHALL WACE, LLP	31 Dec, 2025	1,080,128	780,667	260.69%	$1,317,756.00
BlackRock, Inc.	31 Dec, 2025	1,073,272	-347,591	-24.46%	$1,309,392.00
UBS Group AG	31 Dec, 2025	1,062,615	-259,402	-19.62%	$1,296,390.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	1,045,818	34,016	3.36%	$1,275,898.00
Centiva Capital, LP	31 Dec, 2025	1,000,000	1,000,000	0.00%	$1,220,000.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	953,293	170,038	21.71%	$1,163,017.00
Peapod Lane Capital LLC	31 Dec, 2025	886,374	-210,654	-19.20%	$1,081,376.00
Eversept Partners, LP	31 Dec, 2025	842,023	17,429	2.11%	$1,027,268.00

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