Profusa, Inc. (PFSA) Institutional Ownership

Ownership Summary

A total of 40 institutions have reported a stake in Profusa, Inc. (NASDAQ:PFSA) as of December 2025, according to recent 13F filings with the SEC.

• Institutional ownership in Profusa edged up to 5983.1% in December 2025, compared to 1423.9% in September 2025.
• The company experienced a 390.20% quarterly change in institutional shares held, alongside an increase of 1900.00% in total owners annually.
• During the quarter, 20 institutions bought more Profusa shares, 4 sold shares, and 16 of the 40 total investors held their position steady.
• The total number of shares held by institutions in Profusa increased to 9.19Mn as of December 2025, a net change of up by 7.32Mn shares quarter on quarter, and up 8.42Mn shares year over year.
• With 3.54Mn shares, UBS Group AG commands the largest institutional position in Profusa as of December 31, 2025, equating to 2306.19% of the company.
• Among the most significant buyers of Profusa during December 2025 were UBS Group AG (3.48Mn), UBS Group AG (3.48Mn), JANE STREET GROUP, LLC (69.89K), JANE STREET GROUP, LLC (69.89K), RVW Wealth, LLC (29.30K).
• Leading sellers of Profusa stock in December 2025 included SBI Securities Co., Ltd. (842), SBI Securities Co., Ltd. (842), Tower Research Capital LLC (TRC) (27), Tower Research Capital LLC (TRC) (27).
• The top 10 institutional holders of Profusa for the quarter ending December 2025 included UBS Group AG (3.54Mn), UBS Group AG (3.54Mn), VANGUARD GROUP INC (422.57K), VANGUARD GROUP INC (422.57K), GEODE CAPITAL MANAGEMENT, LLC (157.25K), GEODE CAPITAL MANAGEMENT, LLC (157.25K), Leo Wealth, LLC (149.09K), Leo Wealth, LLC (149.09K), JANE STREET GROUP, LLC (86.92K), JANE STREET GROUP, LLC (86.92K).