Oruka Therapeutics's top three insider shareholders as of September 29, 2026 are Healthcare Capital Partners Iii, L.P. Venrock (TenPercentOwner, 4.15Mn shares), Funds Management Llc Fairmount (Director, 1.13Mn shares), Lawrence Otto Klein (Chief Executive Officer, 923.13K shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Healthcare Capital Partners Iii, L.P. Venrock | TenPercentOwner | 0 | 4,148,428 | 4,148,428 | 62.3% | 27 Feb, 2025 |
| 2 | Funds Management Llc Fairmount | Director, TenPercentOwner | 0 | 1,131,954 | 1,131,954 | 17.0% | 01 Jul, 2026 |
| 3 | Lawrence Otto Klein | Chief Executive Officer | 923,128 | 0 | 923,128 | 13.9% | 15 Sep, 2026 |
| 4 | Laura Lee Sandler | Chief Operating Officer | 235,478 | 0 | 235,478 | 3.5% | 15 Sep, 2026 |
| 5 | Larry Todd Edwards | Chief Commercial Officer | 100,000 | 0 | 100,000 | 1.5% | 25 Aug, 2026 |
| 6 | Carl Dambkowski | Director | 38,743 | 0 | 38,743 | 0.6% | 12 Jun, 2026 |
| 7 | Joana Goncalves | Chief Medical Officer | 31,771 | 0 | 31,771 | 0.5% | 15 Sep, 2026 |
| 8 | Paul T Quinlan | General Counsel | 29,995 | 0 | 29,995 | 0.5% | 21 Sep, 2026 |
| 9 | Arjun Agarwal | Senior Vice President, Finance | 14,219 | 0 | 14,219 | 0.2% | 21 Sep, 2026 |
| 10 | Funds, Lp Funicular | TenPercentOwner, Other | 7 | 0 | 7 | 0.0% | 19 Dec, 2022 |
| 11 | Fund, Lp Funicular | Other | 5 | 0 | 5 | 0.0% | 25 May, 2022 |
| 12 | Henderson Group Plc Janus | TenPercentOwner | 0 | 4 | 4 | 0.0% | 20 Aug, 2024 |
| 13 | Christopher David Ozeroff | S.V.P., General Counsel | 0 | 0 | 0 | 0.0% | 23 Nov, 2021 |
| 14 | C. Jeffrey Dekker | Chief Financial Officer | 0 | 0 | 0 | 0.0% | 09 Dec, 2022 |
| 15 | Thomas A Keuer | Chief Operating Officer | 0 | 0 | 0 | 0.0% | 09 Dec, 2022 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 21 Sep, 2026 | Paul T Quinlan | General Counsel | Acquired M | 10,000 | $7.80 | $78.00K | 39,995 | Direct |
| 21 Sep, 2026 | Arjun Agarwal | Senior Vice President, Finance | Disposed S | 533 | $95.75 | $51.03K | 14,219 | Direct |
| 21 Sep, 2026 | Paul T Quinlan | General Counsel | Disposed S | 2,900 | $92.37 | $267.87K | 37,095 | Direct |
| 21 Sep, 2026 | Paul T Quinlan | General Counsel | Disposed S | 3,832 | $93.32 | $357.59K | 33,263 | Direct |
| 21 Sep, 2026 | Paul T Quinlan | General Counsel | Disposed S | 601 | $94.44 | $56.76K | 32,662 | Direct |
| 21 Sep, 2026 | Paul T Quinlan | General Counsel | Disposed S | 2,667 | $95.31 | $254.20K | 29,995 | Direct |
| 21 Sep, 2026 | Paul T Quinlan | General Counsel | Disposed M | 10,000 | $0.00 | $0 | 79,996 | Direct |
| 01 Sep, 2026 | Laura Lee Sandler | Chief Operating Officer | Acquired M | 5,000 | $7.80 | $39.00K | 241,384 | Direct |
| 01 Sep, 2026 | Lawrence Otto Klein | Chief Executive Officer | Acquired M | 75,000 | $7.80 | $585.00K | 1,000,580 | Direct |
| 01 Sep, 2026 | Laura Lee Sandler | Chief Operating Officer | Disposed S | 1,000 | $91.05 | $91.05K | 240,384 | Direct |
| 01 Sep, 2026 | Lawrence Otto Klein | Chief Executive Officer | Disposed S | 6,604 | $90.79 | $599.56K | 993,976 | Direct |
| 01 Sep, 2026 | Lawrence Otto Klein | Chief Executive Officer | Disposed S | 63,596 | $91.90 | $5.84Mn | 930,380 | Direct |
| 01 Sep, 2026 | Laura Lee Sandler | Chief Operating Officer | Disposed S | 4,000 | $92.01 | $368.05K | 236,384 | Direct |
| 01 Sep, 2026 | Lawrence Otto Klein | Chief Executive Officer | Disposed S | 4,800 | $92.44 | $443.69K | 925,580 | Direct |
| 01 Sep, 2026 | Laura Lee Sandler | Chief Operating Officer | Disposed M | 5,000 | $0.00 | $0 | 74,996 | Direct |
| 01 Sep, 2026 | Lawrence Otto Klein | Chief Executive Officer | Disposed M | 75,000 | $0.00 | $0 | 1,553,513 | Direct |
| 24 Aug, 2026 | Larry Todd Edwards | Chief Commercial Officer | Acquired A | 100,000 | $0.00 | $0 | 100,000 | Direct |
| 24 Aug, 2026 | Larry Todd Edwards | Chief Commercial Officer | Acquired A | 20,000 | $0.00 | $0 | 20,000 | Direct |
| 17 Aug, 2026 | Joana Goncalves | Chief Medical Officer | Acquired M | 3,500 | $6.84 | $23.94K | 36,218 | Direct |
| 17 Aug, 2026 | Joana Goncalves | Chief Medical Officer | Acquired M | 3,500 | $7.80 | $27.30K | 39,718 | Direct |