Oruka Therapeutics's three largest insider shareholders as of August 29, 2026 are Healthcare Capital Partners Iii, L.P. Venrock (TenPercentOwner, 4.15Mn shares), Healthcare Capital Partners Iii, L.P. Venrock (TenPercentOwner, 4.15Mn shares), Funds, Lp Funicular (TenPercentOwner, 4.00Mn shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Healthcare Capital Partners Iii, L.P. Venrock | TenPercentOwner | 0 | 4,148,428 | 4,148,428 | 31.1% | 27 Feb, 2025 |
| 2 | Funds, Lp Funicular | TenPercentOwner, Other | 4,000,452 | 0 | 4,000,452 | 30.0% | 19 Dec, 2022 |
| 3 | Fund, Lp Funicular | Other | 2,580,452 | 0 | 2,580,452 | 19.4% | 25 May, 2022 |
| 4 | Funds Management Llc Fairmount | Director, TenPercentOwner | 0 | 1,131,954 | 1,131,954 | 8.5% | 01 Jul, 2026 |
| 5 | Lawrence Otto Klein | Chief Executive Officer | 925,580 | 0 | 925,580 | 6.9% | 01 Sep, 2026 |
| 6 | Laura Lee Sandler | Chief Operating Officer | 236,384 | 0 | 236,384 | 1.8% | 01 Sep, 2026 |
| 7 | Larry Todd Edwards | Chief Commercial Officer | 100,000 | 0 | 100,000 | 0.8% | 25 Aug, 2026 |
| 8 | Christopher David Ozeroff | S.V.P., General Counsel | 50,970 | 0 | 50,970 | 0.4% | 23 Nov, 2021 |
| 9 | Thomas A Keuer | Chief Operating Officer | 40,730 | 0 | 40,730 | 0.3% | 09 Dec, 2022 |
| 10 | Carl Dambkowski | Director | 38,743 | 0 | 38,743 | 0.3% | 12 Jun, 2026 |
| 11 | Joana Goncalves | Chief Medical Officer | 32,718 | 0 | 32,718 | 0.2% | 17 Aug, 2026 |
| 12 | Paul T Quinlan | General Counsel | 31,034 | 0 | 31,034 | 0.2% | 14 Aug, 2026 |
| 13 | Arjun Agarwal | Senior Vice President, Finance | 15,312 | 0 | 15,312 | 0.1% | 14 Aug, 2026 |
| 14 | Henderson Group Plc Janus | TenPercentOwner | 0 | 4 | 4 | 0.0% | 20 Aug, 2024 |
| 15 | C. Jeffrey Dekker | Chief Financial Officer | 0 | 0 | 0 | 0.0% | 09 Dec, 2022 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 01 Sep, 2026 | Lawrence Otto Klein | Chief Executive Officer | Acquired M | 75,000 | $7.80 | $585.00K | 1,000,580 | Direct |
| 01 Sep, 2026 | Laura Lee Sandler | Chief Operating Officer | Acquired M | 5,000 | $7.80 | $39.00K | 241,384 | Direct |
| 01 Sep, 2026 | Laura Lee Sandler | Chief Operating Officer | Disposed S | 1,000 | $91.05 | $91.05K | 240,384 | Direct |
| 01 Sep, 2026 | Lawrence Otto Klein | Chief Executive Officer | Disposed S | 6,604 | $90.79 | $599.56K | 993,976 | Direct |
| 01 Sep, 2026 | Laura Lee Sandler | Chief Operating Officer | Disposed S | 4,000 | $92.01 | $368.05K | 236,384 | Direct |
| 01 Sep, 2026 | Lawrence Otto Klein | Chief Executive Officer | Disposed S | 63,596 | $91.90 | $5.84Mn | 930,380 | Direct |
| 01 Sep, 2026 | Laura Lee Sandler | Chief Operating Officer | Disposed M | 5,000 | $0.00 | $0 | 74,996 | Direct |
| 01 Sep, 2026 | Lawrence Otto Klein | Chief Executive Officer | Disposed S | 4,800 | $92.44 | $443.69K | 925,580 | Direct |
| 01 Sep, 2026 | Lawrence Otto Klein | Chief Executive Officer | Disposed M | 75,000 | $0.00 | $0 | 1,553,513 | Direct |
| 24 Aug, 2026 | Larry Todd Edwards | Chief Commercial Officer | Acquired A | 100,000 | $0.00 | $0 | 100,000 | Direct |
| 24 Aug, 2026 | Larry Todd Edwards | Chief Commercial Officer | Acquired A | 20,000 | $0.00 | $0 | 20,000 | Direct |
| 17 Aug, 2026 | Joana Goncalves | Chief Medical Officer | Acquired M | 3,500 | $6.84 | $23.94K | 36,218 | Direct |
| 17 Aug, 2026 | Joana Goncalves | Chief Medical Officer | Acquired M | 3,500 | $7.80 | $27.30K | 39,718 | Direct |
| 17 Aug, 2026 | Joana Goncalves | Chief Medical Officer | Disposed S | 900 | $109.65 | $98.69K | 38,818 | Direct |
| 17 Aug, 2026 | Joana Goncalves | Chief Medical Officer | Disposed S | 300 | $110.52 | $33.16K | 38,518 | Direct |
| 17 Aug, 2026 | Joana Goncalves | Chief Medical Officer | Disposed S | 3,320 | $112.01 | $371.89K | 35,198 | Direct |
| 17 Aug, 2026 | Joana Goncalves | Chief Medical Officer | Disposed S | 2,480 | $112.56 | $279.15K | 32,718 | Direct |
| 17 Aug, 2026 | Joana Goncalves | Chief Medical Officer | Disposed M | 3,500 | $0.00 | $0 | 197,063 | Direct |
| 17 Aug, 2026 | Joana Goncalves | Chief Medical Officer | Disposed M | 3,500 | $0.00 | $0 | 168,492 | Direct |
| 14 Aug, 2026 | Paul T Quinlan | General Counsel | Acquired M | 10,000 | $7.80 | $78.00K | 41,034 | Direct |