BeOne Medicines Ltd. (ONC) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

2,285,000,000Shares Outstanding

9,969,586Shares held by institutions

$3,537,807,288Value of institutional holdings

1.42%Institutional ownership %

3.89%Shares Changed QoQ

270No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

A total of 270 institutions have reported a stake in BeOne Medicines Ltd. (NASDAQ:ONC) as of December 2025, according to recent 13F filings with the SEC.

The collective stake of institutional investors in BeOne Medicines moved to 1.4% in December 2025, a shift down from the 1.4% reported for September 2025.
On a quarter-over-quarter basis, institutional holdings shifted by 3.89%, with a year-over-year an increase of 20.54% in the count of filers.
Of these 270 institutional investors, 162 increased their holdings in BeOne Medicines, while 68 of them reduced positions, and 40 investors maintained their exposure.
Collectively, institutional investors increased their stake in BeOne Medicines to 32.44Mn shares as of December 2025, a change that is up by 1.22Mn shares quarter on quarter and down 11.15Mn shares year over year.
As of December 31, 2025, BAKER BROS. ADVISORS LP held BeOne Medicines's largest shareholding position with over 8.80Mn shares, representing 0.39% of total outstanding shares.
Among the most significant buyers of BeOne Medicines during December 2025 were CITADEL ADVISORS LLC (497.31K), FMR LLC (207.69K), BlackRock, Inc. (180.12K), GOLDMAN SACHS GROUP INC (104.48K), BNP PARIBAS FINANCIAL MARKETS (97.24K).
Leading sellers of BeOne Medicines stock in December 2025 included MARSHALL WACE, LLP (160.14K), Nuveen, LLC (112.39K), PRIMECAP MANAGEMENT CO/CA/ (99.88K), Temasek Holdings (Private) Ltd (91.88K), Artisan Partners Limited Partnership (84.60K).
The top 10 institutional holders of BeOne Medicines for the quarter ending December 2025 included BAKER BROS. ADVISORS LP (8.80Mn), Capital International Investors (5.11Mn), PRIMECAP MANAGEMENT CO/CA/ (4.98Mn), FMR LLC (3.99Mn), HHLR ADVISORS, LTD. (1.03Mn), Temasek Holdings (Private) Ltd (919.59K), BlackRock, Inc. (676.21K), CITADEL ADVISORS LLC (533.52K), Siren, L.L.C. (500.00K), MORGAN STANLEY (437.66K).

270 Institutional Holders

9,969,586 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BAKER BROS. ADVISORS LP	31 Dec, 2025	8,799,053	0	0.00%	$2,673,240,292.00
Capital International Investors	31 Dec, 2025	5,113,866	67,808	1.34%	$1,553,909,094.00
PRIMECAP MANAGEMENT CO/CA/	31 Dec, 2025	4,980,581	-99,880	-1.97%	$1,513,150,314.00
FMR LLC	31 Dec, 2025	3,992,627	207,692	5.49%	$1,213,000,071.00
HHLR ADVISORS, LTD.	31 Dec, 2025	1,034,306	0	0.00%	$314,232,506.00
Temasek Holdings (Private) Ltd	31 Dec, 2025	919,587	-91,877	-9.08%	$279,379,726.00
BlackRock, Inc.	31 Dec, 2025	676,210	180,120	36.31%	$205,439,150.00
CITADEL ADVISORS LLC	31 Dec, 2025	533,517	497,312	1,373.60%	$162,087,800.00
Siren, L.L.C.	31 Dec, 2025	500,000	7,010	1.42%	$151,905,000.00
MORGAN STANLEY	31 Dec, 2025	437,661	84,367	23.88%	$132,966,412.00
BANK OF AMERICA CORP /DE/	31 Dec, 2025	378,832	33,576	9.72%	$115,093,010.00
Capital International, Inc./CA/	31 Dec, 2025	307,660	-18,184	-5.58%	$93,470,185.00
Baird Financial Group, Inc.	31 Dec, 2025	304,339	-38,583	-11.25%	$92,461,232.00
Man Group plc	31 Dec, 2025	248,514	39,498	18.90%	$75,501,038.00
Candriam S.C.A.	31 Dec, 2025	197,261	-15,307	-7.20%	$59,932,416.00
Nuveen, LLC	31 Dec, 2025	194,124	-112,387	-36.67%	$58,976,812.00
BNP PARIBAS FINANCIAL MARKETS	31 Dec, 2025	193,951	97,244	100.56%	$58,924,253.00
Artisan Partners Limited Partnership	31 Dec, 2025	165,241	-84,603	-33.86%	$50,201,868.00
Capital International Sarl	31 Dec, 2025	152,515	3,956	2.66%	$46,335,582.00
MARSHALL WACE, LLP	31 Dec, 2025	152,296	-160,141	-51.26%	$46,269,049.00

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