Neurogene Inc. (NGNE) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

21,168,431Shares Outstanding

16,699,072Shares held by institutions

$427,496,243Value of institutional holdings

78.89%Institutional ownership %

10.81%Shares Changed QoQ

92No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Neurogene Inc. (NASDAQ:NGNE) showed up in the 13F filings of 92 institutional investors as of December 2025.

Their combined ownership stood at 78.1% of outstanding shares in December 2025, up from 72.4% in September 2025.
Their total shares held in NGNE increased 9.95% from the prior quarter, while the number of investors in Neurogene increased 3.37% year over year.
Among the 92 funds, 38 bought more Neurogene shares, 30 sold down, and 24 held their ground.
Combined, these investors held 16.54Mn shares in NGNE for December 2025, up by 1.5Mn shares quarter on quarter, and down 41.58K shares year over year.
As of December 31, 2025, Samsara BioCapital, LLC held the largest stake in Neurogene with 1.72Mn shares, accounting for 8.11% of total shares outstanding.
The biggest buyers of Neurogene for the quarter ending December 2025 included Trails Edge Capital Partners, LP (785.0K), CITADEL ADVISORS LLC (364.23K), Goldman Sachs Group Inc (251.23K), Logos Global Management LP (195.0K), Redmile Group, LLC (160.58K).
The largest sales of NGNE for the quarter ending December 2025 came from MILLENNIUM MANAGEMENT LLC (176.54K), GREAT POINT PARTNERS LLC (96.81K), BALYASNY ASSET MANAGEMENT L.P. (90.42K), UBS Group AG (73.59K), DEUTSCHE BANK AG\ (66.71K).
Business Quant data shows the 10 biggest positions in Neurogene as of December 2025 are held by Samsara BioCapital, LLC (1.72Mn), Redmile Group, LLC (1.46Mn), RTW INVESTMENTS, LP (1.36Mn), Casdin Capital, LLC (1.3Mn), EcoR1 Capital, LLC (1.27Mn), BAKER BROS. ADVISORS LP (991.69K), BlackRock, Inc. (945.58K), Trails Edge Capital Partners, LP (785.0K), Toronto Dominion Bank (681.34K), VANGUARD GROUP INC (656.57K).

92 Institutional Holders

16,699,072 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Samsara BioCapital, LLC	31 Dec, 2025	1,717,127	0	0.00%	$35,372,816.00
Redmile Group, LLC	31 Dec, 2025	1,459,599	160,577	12.36%	$30,067,739.00
RTW INVESTMENTS, LP	31 Dec, 2025	1,362,456	0	0.00%	$28,066,594.00
Casdin Capital, LLC	31 Dec, 2025	1,295,361	0	0.00%	$26,684,437.00
EcoR1 Capital, LLC	31 Dec, 2025	1,271,342	0	0.00%	$26,189,645.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	991,691	0	0.00%	$20,428,835.00
BlackRock, Inc.	31 Dec, 2025	945,583	-5,517	-0.58%	$19,479,009.00
Trails Edge Capital Partners, LP	31 Dec, 2025	785,000	785,000	0.00%	$16,171,000.00
Toronto Dominion Bank	31 Dec, 2025	681,337	0	0.00%	$14,035,542.00
VANGUARD GROUP INC	31 Dec, 2025	656,572	51,961	8.59%	$13,525,383.00
BALYASNY ASSET MANAGEMENT L.P.	31 Dec, 2025	608,578	-90,424	-12.94%	$12,536,710.00
ArrowMark Colorado Holdings LLC	31 Dec, 2025	577,490	-18,349	-3.08%	$11,896,294.00
JENNISON ASSOCIATES LLC	31 Dec, 2025	533,088	138,999	35.27%	$10,981,614.00
Morgan Stanley	31 Dec, 2025	371,174	-55,402	-12.99%	$7,646,185.00
CITADEL ADVISORS LLC	31 Dec, 2025	364,228	364,228	0.00%	$7,503,097.00
GREAT POINT PARTNERS LLC	31 Dec, 2025	350,000	-96,814	-21.67%	$7,210,000.00
Goldman Sachs Group Inc	31 Dec, 2025	324,036	251,234	345.09%	$6,675,142.00
State Street Corp	31 Dec, 2025	307,797	99,487	47.76%	$6,340,618.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	249,695	3,262	1.32%	$5,144,591.00
Logos Global Management LP	31 Dec, 2025	195,000	195,000	0.00%	$4,017,000.00

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