Mereo BioPharma Group plc (MREO) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

799,947,013Shares Outstanding

62,213,085Shares held by institutions

$20,300,130Value of institutional holdings

7.78%Institutional ownership %

56.81%Shares Changed QoQ

70No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Mereo BioPharma Group plc (NASDAQ:MREO) showed up in the 13F filings of 70 institutional investors as of December 2025.

Their combined ownership stood at 7.8% of outstanding shares in December 2025, down from 12.7% in September 2025.
They increased total shares held in MREO by 56.73% quarter over quarter, and investors in Mereo BioPharma decreased 23.08% from a year ago.
Activity in MREO broke down as 37 buyers, 20 sellers, and 13 unchanged among 70 total holders.
In total, institutional investors held 62.18Mn shares in Mereo BioPharma as of December 2025, up by 22.51Mn shares quarter on quarter, and down 56.74Mn shares year over year.
As of December 31, 2025, the biggest holder of Mereo BioPharma is Rubric Capital Management LP at 15.31Mn shares, representing 1.91% of shares outstanding.
Leading buyers of Mereo BioPharma shares for the quarter ending December 2025 were 683 Capital Management, LLC (10.15Mn), EcoR1 Capital, LLC (7.86Mn), Schonfeld Strategic Advisors LLC (4.36Mn), Logos Global Management LP (1.35Mn), BALYASNY ASSET MANAGEMENT L.P. (1.28Mn).
Top sellers of MREO stock for the quarter ending December 2025 included Goldman Sachs Group Inc (2.31Mn), Morgan Stanley (2.07Mn), Bank Of America Corp /De/ (851.75K), TWO SIGMA INVESTMENTS, LP (562.97K), RENAISSANCE TECHNOLOGIES LLC (396.5K).
Mereo BioPharma's 10 largest shareholders as of December 2025 include Rubric Capital Management LP (15.31Mn), 683 Capital Management, LLC (15.02Mn), EcoR1 Capital, LLC (7.86Mn), Schonfeld Strategic Advisors LLC (6.09Mn), Tejara Capital Ltd (2.16Mn), Logos Global Management LP (1.85Mn), UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC (1.76Mn), Monaco Asset Management SAM (1.59Mn), UBS Group AG (1.56Mn), BALYASNY ASSET MANAGEMENT L.P. (1.28Mn) per Business Quant data.

70 Institutional Holders

62,213,085 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Rubric Capital Management LP	31 Dec, 2025	15,307,347	0	0.00%	$6,378,572.00
683 Capital Management, LLC	31 Dec, 2025	15,025,000	10,150,000	208.21%	$6,260,917.00
EcoR1 Capital, LLC	31 Dec, 2025	7,856,466	7,856,466	0.00%	$3,273,789.00
Schonfeld Strategic Advisors LLC	31 Dec, 2025	6,090,381	4,357,657	251.49%	$2,537,860.00
Tejara Capital Ltd	31 Dec, 2025	2,159,681	252,837	13.26%	$899,939.00
Logos Global Management LP	31 Dec, 2025	1,850,000	1,350,000	270.00%	$770,895.00
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	31 Dec, 2025	1,763,666	-143,109	-7.51%	$735,449.00
Monaco Asset Management SAM	31 Dec, 2025	1,585,214	639,299	67.59%	$660,559.00
UBS Group AG	31 Dec, 2025	1,558,931	588,264	60.60%	$650,074.00
BALYASNY ASSET MANAGEMENT L.P.	31 Dec, 2025	1,280,275	1,280,275	0.00%	$533,491.00
Morgan Stanley	31 Dec, 2025	1,273,785	-2,072,562	-61.94%	$530,787.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	525,125	-562,971	-51.74%	$218,820.00
GROUP ONE TRADING LLC	31 Dec, 2025	441,636	305,048	223.33%	$184,030.00
SIMPLEX TRADING, LLC	31 Dec, 2025	419,477	223,208	113.73%	$174,921.00
EntryPoint Capital, LLC	31 Dec, 2025	400,700	400,700	0.00%	$166,972.00
LUMINUS MANAGEMENT LLC	31 Dec, 2025	395,000	395,000	0.00%	$164,596.00
Rangeley Capital, LLC	31 Dec, 2025	364,000	364,000	0.00%	$151,679.00
JANE STREET GROUP, LLC	31 Dec, 2025	356,004	-96,358	-21.30%	$148,347.00
BlackRock, Inc.	31 Dec, 2025	312,613	-131,391	-29.59%	$130,265.00
Knott David M Jr	31 Dec, 2025	300,337	0	0.00%	$125,150.00

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