Mereo BioPharma Group plc (MREO) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

175,613,333Shares Outstanding

30,073,551Shares held by institutions

$12,630,891Value of institutional holdings

48.63%Institutional ownership %

10.59%Shares Changed QoQ

81No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Mereo BioPharma Group plc (NASDAQ:MREO) currently has 70 active institutional owners and shareholders as of today (December 2025), that have filed 13F forms with the Securities Exchange Commission (SEC).

Institutional ownership in Mereo BioPharma edged down to 46.5% in December 2025, compared to 73.1% in September 2025.
The company experienced a 58.07% quarterly change in institutional shares held, alongside a decrease of 23.08% in total owners annually.
During the quarter, 39 institutions bought more Mereo BioPharma shares, 18 sold shares, and 13 of the 70 total investors held their position steady.
This class of investors increased its holdings in Mereo BioPharma to 65.28Mn shares for the 13F-cycle ending December 2025, up by 23.98Mn shares quarter on quarter, and down 50.18Mn shares year over year.
The top institutional stake in Mereo BioPharma as of December 31, 2025 belongs to Rubric Capital Management LP, which owns 15.31Mn shares, or 10.90% of the company.
Among the most significant buyers of Mereo BioPharma during December 2025 were 683 Capital Management, LLC (10.15Mn), EcoR1 Capital, LLC (7.86Mn), Schonfeld Strategic Advisors LLC (4.36Mn), Logos Global Management LP (1.35Mn), BALYASNY ASSET MANAGEMENT L.P. (1.28Mn).
Leading sellers of Mereo BioPharma stock in December 2025 included GOLDMAN SACHS GROUP INC (2.34Mn), MORGAN STANLEY (2.07Mn), TWO SIGMA INVESTMENTS, LP (562.97K), Caption Management, LLC (520.41K), BANK OF AMERICA CORP /DE/ (413.13K).
The top 10 institutional holders of Mereo BioPharma for the quarter ending December 2025 included Rubric Capital Management LP (15.31Mn), 683 Capital Management, LLC (15.03Mn), EcoR1 Capital, LLC (7.86Mn), Schonfeld Strategic Advisors LLC (6.09Mn), Tejara Capital Ltd (2.16Mn), DIADEMA PARTNERS LP (2.00Mn), Logos Global Management LP (1.85Mn), UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC (1.76Mn), Monaco Asset Management SAM (1.59Mn), UBS Group AG (1.56Mn).

70 Institutional Holders

30,073,551 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Rubric Capital Management LP	31 Dec, 2025	15,307,347	0	0.00%	$6,378,572.00
683 Capital Management, LLC	31 Dec, 2025	15,025,000	10,150,000	208.21%	$6,260,917.00
EcoR1 Capital, LLC	31 Dec, 2025	7,856,466	7,856,466	0.00%	$3,273,789.00
Schonfeld Strategic Advisors LLC	31 Dec, 2025	6,090,381	4,357,657	251.49%	$2,537,860.00
Tejara Capital Ltd	31 Dec, 2025	2,159,681	252,837	13.26%	$899,939.00
DIADEMA PARTNERS LP	31 Dec, 2025	1,999,500	439,900	28.21%	$833,192.00
Logos Global Management LP	31 Dec, 2025	1,850,000	1,350,000	270.00%	$770,895.00
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	31 Dec, 2025	1,763,666	-143,109	-7.51%	$735,449.00
Monaco Asset Management SAM	31 Dec, 2025	1,585,214	639,299	67.59%	$660,559.00
UBS Group AG	31 Dec, 2025	1,558,931	588,264	60.60%	$650,074.00
BALYASNY ASSET MANAGEMENT L.P.	31 Dec, 2025	1,280,275	1,280,275	0.00%	$533,491.00
MORGAN STANLEY	31 Dec, 2025	1,273,785	-2,072,562	-61.94%	$530,787.00
JANE STREET GROUP, LLC	31 Dec, 2025	873,704	389,142	80.31%	$364,073.00
DLD Asset Management, LP	31 Dec, 2025	746,000	627,000	526.89%	$310,858.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	525,125	-562,971	-51.74%	$218,820.00
GROUP ONE TRADING LLC	31 Dec, 2025	441,636	305,048	223.33%	$184,030.00
SIMPLEX TRADING, LLC	31 Dec, 2025	419,477	223,208	113.73%	$174,921.00
EntryPoint Capital, LLC	31 Dec, 2025	400,700	400,700	0.00%	$166,972.00
LUMINUS MANAGEMENT LLC	31 Dec, 2025	395,000	395,000	0.00%	$164,596.00
Rangeley Capital, LLC	31 Dec, 2025	364,000	364,000	0.00%	$151,679.00

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