Mereo BioPharma Group plc (MREO) Institutional Ownership

Institutions by Trading Activity

799,947,013Shares Outstanding

62,213,085Shares held by institutions

$16,772,648Value of institutional holdings

7.78%Institutional ownership %

56.81%Shares Changed QoQ

70No. of institutional investors

Mereo BioPharma Group plc (NASDAQ:MREO) appears in 70 institutional 13F filings for the quarter ending December 2025.

Collectively, these holders controlled 7.8% of Mereo BioPharma's outstanding shares in December 2025, down from 12.7% in September 2025.
They increased total shares held in Mereo BioPharma by 56.73% from last quarter, and the number of investors in MREO decreased 23.08% annually.
Of these 70 funds, 37 grew their exposure to Mereo BioPharma, 20 cut back, and 13 maintained positions.
The aggregate institutional position in Mereo BioPharma amounted to 62.18Mn shares as of December 2025, up by 22.51Mn shares quarter on quarter, and down 56.74Mn shares year over year.
SmartHarvest Portfolios, LLC holds the largest position in MREO at 49.51K shares as of December 31, 2025, or 0.01% of shares outstanding.
The biggest buyers of Mereo BioPharma for the quarter ending December 2025 included SmartHarvest Portfolios, LLC (29.22K), GAMMA Investing LLC (9.71K), Significant Wealth Partners LLC (3.94K).
Business Quant data shows the 4 biggest positions in Mereo BioPharma as of December 2025 are held by SmartHarvest Portfolios, LLC (49.51K), Significant Wealth Partners LLC (25.63K), GAMMA Investing LLC (19.27K), Three Magnolias Financial Advisors, LLC (19.0K).

62,213,085 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Rubric Capital Management LP	31 Dec, 2025	15,307,347	0	0.00%	$6,378,572.00
683 Capital Management, LLC	31 Dec, 2025	15,025,000	10,150,000	208.21%	$6,260,917.00
EcoR1 Capital, LLC	31 Dec, 2025	7,856,466	7,856,466	0.00%	$3,273,789.00
Schonfeld Strategic Advisors LLC	31 Dec, 2025	6,090,381	4,357,657	251.49%	$2,537,860.00
Tejara Capital Ltd	31 Dec, 2025	2,159,681	252,837	13.26%	$899,939.00
Logos Global Management LP	31 Dec, 2025	1,850,000	1,350,000	270.00%	$770,895.00
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	31 Dec, 2025	1,763,666	-143,109	-7.51%	$735,449.00
Monaco Asset Management SAM	31 Dec, 2025	1,585,214	639,299	67.59%	$660,559.00
UBS Group AG	31 Dec, 2025	1,558,931	588,264	60.60%	$650,074.00
BALYASNY ASSET MANAGEMENT L.P.	31 Dec, 2025	1,280,275	1,280,275	0.00%	$533,491.00
Morgan Stanley	31 Dec, 2025	1,273,785	-2,072,562	-61.94%	$530,787.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	525,125	-562,971	-51.74%	$218,820.00
GROUP ONE TRADING LLC	31 Dec, 2025	441,636	305,048	223.33%	$184,030.00
SIMPLEX TRADING, LLC	31 Dec, 2025	419,477	223,208	113.73%	$174,921.00
EntryPoint Capital, LLC	31 Dec, 2025	400,700	400,700	0.00%	$166,972.00
LUMINUS MANAGEMENT LLC	31 Dec, 2025	395,000	395,000	0.00%	$164,596.00
Rangeley Capital, LLC	31 Dec, 2025	364,000	364,000	0.00%	$151,679.00
JANE STREET GROUP, LLC	31 Dec, 2025	356,004	-96,358	-21.30%	$148,347.00
BlackRock, Inc.	31 Dec, 2025	312,613	-131,391	-29.59%	$130,265.00
Knott David M Jr	31 Dec, 2025	300,337	0	0.00%	$125,150.00

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