Kymera Therapeutics, Inc. (KYMR) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

81,978,333Shares Outstanding

7,350,660Shares held by institutions

$623,629,994Value of institutional holdings

100.88%Institutional ownership %

10.44%Shares Changed QoQ

244No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Kymera Therapeutics, Inc. (NASDAQ:KYMR) includes 244 filers as of the latest reporting cycle ending December 2025.

Kymera Therapeutics saw its institutional ownership percentage rose to 100.9% in December 2025 from 98.7% in September 2025.
On a quarter-over-quarter basis, institutional holdings shifted by 10.44%, with a year-over-year an increase of 36.31% in the count of filers.
Of these 244 institutional investors, 156 increased their holdings in Kymera Therapeutics, while 62 of them reduced positions, and 26 investors maintained their exposure.
This class of investors increased its holdings in Kymera Therapeutics to 82.70Mn shares for the 13F-cycle ending December 2025, up by 7.82Mn shares quarter on quarter, and up 11.19Mn shares year over year.
As of December 31, 2025, FMR LLC held Kymera Therapeutics's largest shareholding position with over 8.93Mn shares, representing 10.89% of total outstanding shares.
Among the most significant buyers of Kymera Therapeutics during December 2025 were FMR LLC (3.05Mn), BAKER BROS. ADVISORS LP (2.01Mn), Avoro Capital Advisors LLC (1.12Mn), ALLIANCEBERNSTEIN L.P. (903.30K), VANGUARD GROUP INC (845.92K).
Leading sellers of Kymera Therapeutics stock in December 2025 included WELLINGTON MANAGEMENT GROUP LLP (782.76K), JENNISON ASSOCIATES LLC (531.07K), T. Rowe Price Investment Management, Inc. (514.39K), AJU IB Investment Co., Ltd. (437.41K), MARSHALL WACE, LLP (321.05K).
The top 10 institutional holders of Kymera Therapeutics for the quarter ending December 2025 included FMR LLC (8.93Mn), BAKER BROS. ADVISORS LP (8.66Mn), Avoro Capital Advisors LLC (7.47Mn), VANGUARD GROUP INC (6.27Mn), BVF INC/IL (5.50Mn), BlackRock, Inc. (5.00Mn), Atlas Venture Life Science Advisors, LLC (4.66Mn), WELLINGTON MANAGEMENT GROUP LLP (4.41Mn), Siren, L.L.C. (3.29Mn), STATE STREET CORP (2.21Mn).

244 Institutional Holders

7,350,660 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
FMR LLC	31 Dec, 2025	8,928,574	3,048,963	51.86%	$694,732,353.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	8,657,242	2,005,813	30.16%	$673,620,000.00
Avoro Capital Advisors LLC	31 Dec, 2025	7,474,747	1,124,747	17.71%	$581,610,064.00
VANGUARD GROUP INC	31 Dec, 2025	6,267,644	845,922	15.60%	$487,685,380.00
BVF INC/IL	31 Dec, 2025	5,502,710	0	0.00%	$428,165,865.00
BlackRock, Inc.	31 Dec, 2025	5,004,095	638,647	14.63%	$389,368,651.00
Atlas Venture Life Science Advisors, LLC	31 Dec, 2025	4,659,874	-236,588	-4.83%	$362,584,796.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	4,412,933	-782,758	-15.07%	$343,370,317.00
Siren, L.L.C.	31 Dec, 2025	3,286,830	-141,320	-4.12%	$255,748,242.00
STATE STREET CORP	31 Dec, 2025	2,209,837	190,383	9.43%	$171,947,417.00
Capital Research Global Investors	31 Dec, 2025	1,560,791	298,609	23.66%	$121,445,148.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,417,389	140,623	11.01%	$110,306,963.00
DRIEHAUS CAPITAL MANAGEMENT LLC	31 Dec, 2025	1,069,238	130,144	13.86%	$83,197,409.00
ALLIANCEBERNSTEIN L.P.	31 Dec, 2025	952,065	903,296	1,852.19%	$74,080,178.00
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	31 Dec, 2025	912,498	48,736	5.64%	$71,001,470.00
Merck & Co., Inc.	31 Dec, 2025	772,165	0	0.00%	$60,082,159.00
FEDERATED HERMES, INC.	31 Dec, 2025	763,920	205,220	36.73%	$59,440,615.00
Holocene Advisors, LP	31 Dec, 2025	761,209	-79,124	-9.42%	$59,229,672.00
Commodore Capital LP	31 Dec, 2025	750,000	0	0.00%	$58,357,500.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	740,306	28,862	4.06%	$57,603,210.00

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