Kymera Therapeutics, Inc. (KYMR) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

87,300,286Shares Outstanding

91,714,464Shares held by institutions

$7,915,875,388Value of institutional holdings

105.06%Institutional ownership %

20.77%Shares Changed QoQ

249No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Kymera Therapeutics, Inc. (NASDAQ:KYMR) is held by 249 institutional investors per 13F filings through December 2025.

Their combined ownership stood at 95.6% of outstanding shares in December 2025, up from 93.5% in September 2025.
Their total shares held in KYMR increased 10.27% from the prior quarter, while the number of investors in Kymera Therapeutics increased 39.11% year over year.
Activity in KYMR broke down as 157 buyers, 67 sellers, and 25 unchanged among 249 total holders.
In total, institutional investors held 83.47Mn shares in Kymera Therapeutics as of December 2025, up by 7.77Mn shares quarter on quarter, and up 11.46Mn shares year over year.
Avoro Capital Advisors LLC leads ownership in KYMR with 14.95Mn shares as of December 31, 2025, equal to 17.12% of outstanding shares.
Leading buyers of Kymera Therapeutics shares for the quarter ending December 2025 were Avoro Capital Advisors LLC (8.6Mn), FMR LLC (3.05Mn), BAKER BROS. ADVISORS LP (2.01Mn), ALLIANCEBERNSTEIN L.P. (903.3K), VANGUARD GROUP INC (845.92K).
The largest sellers of Kymera Therapeutics for the quarter ending December 2025 were WELLINGTON MANAGEMENT GROUP LLP (782.76K), JENNISON ASSOCIATES LLC (531.07K), AJU IB Investment Co., Ltd. (437.41K), MARSHALL WACE, LLP (321.05K), Boxer Capital Management, LLC (309.1K).
Business Quant data shows the 10 biggest positions in Kymera Therapeutics as of December 2025 are held by Avoro Capital Advisors LLC (14.95Mn), FMR LLC (8.93Mn), BAKER BROS. ADVISORS LP (8.66Mn), VANGUARD GROUP INC (6.27Mn), BVF INC/IL (5.5Mn), BlackRock, Inc. (5.0Mn), Atlas Venture Life Science Advisors, LLC (4.66Mn), WELLINGTON MANAGEMENT GROUP LLP (4.41Mn), Siren, L.L.C. (3.29Mn), State Street Corp (2.21Mn).

249 Institutional Holders

91,714,464 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Avoro Capital Advisors LLC	31 Dec, 2025	14,949,494	8,599,494	135.43%	$1,163,220,128.00
FMR LLC	31 Dec, 2025	8,928,574	3,048,963	51.86%	$694,732,353.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	8,657,242	2,005,813	30.16%	$673,620,000.00
VANGUARD GROUP INC	31 Dec, 2025	6,267,644	845,922	15.60%	$487,685,380.00
BVF INC/IL	31 Dec, 2025	5,502,710	0	0.00%	$428,165,865.00
BlackRock, Inc.	31 Dec, 2025	5,004,095	638,647	14.63%	$389,368,651.00
Atlas Venture Life Science Advisors, LLC	31 Dec, 2025	4,659,874	-236,588	-4.83%	$362,584,796.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	4,412,933	-782,758	-15.07%	$343,370,317.00
Siren, L.L.C.	31 Dec, 2025	3,286,830	-141,320	-4.12%	$255,748,242.00
State Street Corp	31 Dec, 2025	2,209,837	190,383	9.43%	$171,947,417.00
Capital Research Global Investors	31 Dec, 2025	1,560,791	298,609	23.66%	$121,445,148.00
Goldman Sachs Group Inc	31 Dec, 2025	1,480,612	769,168	108.11%	$115,206,420.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,417,389	140,623	11.01%	$110,306,963.00
DRIEHAUS CAPITAL MANAGEMENT LLC	31 Dec, 2025	1,069,238	130,144	13.86%	$83,197,409.00
ALLIANCEBERNSTEIN L.P.	31 Dec, 2025	952,065	903,296	1,852.19%	$74,080,178.00
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	31 Dec, 2025	912,498	48,736	5.64%	$71,001,470.00
Merck & Co., Inc.	31 Dec, 2025	772,165	0	0.00%	$60,082,159.00
Federated Hermes, Inc.	31 Dec, 2025	763,920	205,220	36.73%	$59,440,615.00
Holocene Advisors, LP	31 Dec, 2025	761,209	-79,124	-9.42%	$59,229,672.00
Commodore Capital LP	31 Dec, 2025	750,000	0	0.00%	$58,357,500.00

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