iSpecimen Inc. (ISPC) Institutional Ownership

Ownership Summary

The institutional landscape for iSpecimen Inc. (NASDAQ:ISPC) includes 12 filers as of the latest reporting cycle ending September 2025.

• iSpecimen saw its institutional ownership percentage rose to 23.5% in September 2025 from 1.9% in June 2025.
• Institutional share ownership changed by 1338.36% QoQ, while the number of institutional owners saw an increase of 71.43% YoY.
• A review of institutional activity for iSpecimen shows 8 of 12 filers increasing their positions, while 2 reduced their stake, and 2 remained unchanged.
• The total number of shares held by institutions in iSpecimen increased to 343.09K as of September 2025, a net change of up by 319.24K shares quarter on quarter, and up 304.17K shares year over year.
• RENAISSANCE TECHNOLOGIES LLC's holding of 153.46K shares as of September 30, 2025 makes it the primary institutional investor in iSpecimen, owning 10.50% of the stock.
• Among the most significant buyers of iSpecimen during September 2025 were RENAISSANCE TECHNOLOGIES LLC (153.46K), Virtu Financial LLC (63.26K), Scientech Research LLC (29.49K), VANGUARD GROUP INC (29.41K), GEODE CAPITAL MANAGEMENT, LLC (26.88K).
• Leading sellers of iSpecimen stock in September 2025 included Tower Research Capital LLC (TRC) (3.83K), SBI Securities Co., Ltd. (3).
• The top 10 institutional holders of iSpecimen for the quarter ending September 2025 included RENAISSANCE TECHNOLOGIES LLC (153.46K), Virtu Financial LLC (63.26K), GEODE CAPITAL MANAGEMENT, LLC (41.69K), Scientech Research LLC (29.49K), VANGUARD GROUP INC (29.41K), JANE STREET GROUP, LLC (20.26K), BlackRock, Inc. (2.83K), Tower Research Capital LLC (TRC) (2.36K), FMR LLC (300), BANK OF AMERICA CORP /DE/ (45).