Disc Medicine, Inc. (IRON) Institutional Ownership

Ownership Summary

Disc Medicine, Inc. (NASDAQ:IRON) has 192 institutional investors with active 13F positions as of December 2025.

• Collectively, these holders controlled 103.5% of Disc Medicine's outstanding shares in December 2025, up from 100.1% in September 2025.
• They increased total shares held in Disc Medicine by 13.09% from the prior quarter, while the number of investors in IRON increased 28.0% year over year.
• Activity in IRON broke down as 125 buyers, 48 sellers, and 19 unchanged among 192 total holders.
• Combined, these investors held 36.41Mn shares in IRON for December 2025, up by 4.21Mn shares quarter on quarter, and up 9.56Mn shares year over year.
• As of December 31, 2025, the biggest holder of Disc Medicine is FMR LLC at 5.59Mn shares, representing 15.88% of shares outstanding.
• The most significant purchases of IRON for the quarter ending December 2025 came from PRICE T ROWE ASSOCIATES INC /MD/ (1.55Mn), VANGUARD CAPITAL MANAGEMENT LLC (1.38Mn), TCG Crossover Management, LLC (1.34Mn), BVF INC/IL (622.31K), State Street Corp (510.25K).
• Top sellers of IRON stock for the quarter ending December 2025 included Goldman Sachs Group Inc (868.55K), Jpmorgan Chase & Co (209.65K), Checkpoint Capital L.P. (166.33K), Nantahala Capital Management, LLC (107.15K), MILLENNIUM MANAGEMENT LLC (101.52K).
• According to Business Quant data, leading holders of IRON for December 2025 are FMR LLC (5.59Mn), RA CAPITAL MANAGEMENT, L.P. (2.45Mn), BlackRock, Inc. (2.27Mn), WELLINGTON MANAGEMENT GROUP LLP (1.74Mn), State Street Corp (1.7Mn), PRICE T ROWE ASSOCIATES INC /MD/ (1.55Mn), Atlas Venture Life Science Advisors, LLC (1.51Mn), VANGUARD CAPITAL MANAGEMENT LLC (1.38Mn), Jpmorgan Chase & Co (1.37Mn), Frazier Life Sciences Management, L.P. (1.35Mn).