Disc Medicine, Inc. (IRON) Institutional Ownership

Ownership Summary

Disc Medicine, Inc. (NASDAQ:IRON) is held by 192 institutional investors per 13F filings through December 2025.

• They owned 103.5% of outstanding stock in December 2025, up from 100.1% the prior quarter.
• They increased total shares held in Disc Medicine by 13.09% from last quarter, and the number of investors in IRON increased 28.0% annually.
• During the quarter, 125 of these 192 funds increased positions in IRON, 48 reduced exposure, and 19 held steady.
• In total, institutional investors held 36.41Mn shares in Disc Medicine as of December 2025, up by 4.21Mn shares quarter on quarter, and up 9.56Mn shares year over year.
• FMR LLC holds the largest position in IRON at 5.45Mn shares as of December 31, 2025, or 15.49% of shares outstanding.
• The most significant purchases of IRON for the quarter ending December 2025 came from BVF INC/IL (650.0K), JENNISON ASSOCIATES LLC (532.08K), FMR LLC (515.06K), PERCEPTIVE ADVISORS LLC (450.74K), RA CAPITAL MANAGEMENT, L.P. (399.03K).
• The largest sellers of Disc Medicine for the quarter ending December 2025 were Atlas Venture Life Science Advisors, LLC (628.74K), DEERFIELD MANAGEMENT COMPANY, L.P. (408.24K), Janus Henderson Group Plc (350.15K), ORBIMED ADVISORS LLC (347.47K), First Turn Management, LLC (244.49K).
• Disc Medicine's 10 largest shareholders as of December 2025 include FMR LLC (5.45Mn), BlackRock, Inc. (2.27Mn), RA CAPITAL MANAGEMENT, L.P. (1.98Mn), VANGUARD GROUP INC (1.77Mn), Jpmorgan Chase & Co (1.58Mn), WELLINGTON MANAGEMENT GROUP LLP (1.52Mn), Atlas Venture Life Science Advisors, LLC (1.51Mn), Frazier Life Sciences Management, L.P. (1.26Mn), State Street Corp (1.19Mn), ORBIMED ADVISORS LLC (1.07Mn) per Business Quant data.