Disc Medicine's top three insider shareholders as of September 29, 2026 are Dmi Llc Ai (TenPercentOwner, 2.81Mn shares), Venture Fund X, L.P. Atlas (TenPercentOwner, 1.60Mn shares), Holdings A/S Novo (TenPercentOwner, 1.09Mn shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Dmi Llc Ai | TenPercentOwner | 2,814,379 | 0 | 2,814,379 | 43.0% | 24 Oct, 2025 |
| 2 | Venture Fund X, L.P. Atlas | TenPercentOwner | 1,402,186 | 198,326 | 1,600,512 | 24.4% | 25 Jan, 2024 |
| 3 | Holdings A/S Novo | TenPercentOwner | 1,090,772 | 0 | 1,090,772 | 16.7% | 28 Jun, 2023 |
| 4 | John D Quisel | Chief Executive Officer | 262,064 | 0 | 262,064 | 4.0% | 16 Sep, 2026 |
| 5 | Advisors Llc Orbimed | Director | 0 | 186,541 | 186,541 | 2.8% | 26 Mar, 2025 |
| 6 | Mona Ashiya | Director | 0 | 186,541 | 186,541 | 2.8% | 26 Mar, 2025 |
| 7 | Pamela Stephenson | Chief Commercial Officer | 80,998 | 0 | 80,998 | 1.2% | 17 Feb, 2026 |
| 8 | William Jacob Savage | Chief Medical Officer | 79,480 | 0 | 79,480 | 1.2% | 15 Apr, 2026 |
| 9 | Jean M. Franchi | Chief Financial Officer | 64,333 | 0 | 64,333 | 1.0% | 15 Apr, 2026 |
| 10 | Jonathan Yen-Wen Yu | Chief Operating Officer | 54,324 | 0 | 54,324 | 0.8% | 26 Aug, 2026 |
| 11 | Rahul Khara | Chief Legal Officer | 52,324 | 0 | 52,324 | 0.8% | 07 Aug, 2026 |
| 12 | Braden Michael Leonard | TenPercentOwner | 24,750 | 0 | 24,750 | 0.4% | 27 Oct, 2022 |
| 13 | Joanne Bryce | Chief Financial Officer | 23,665 | 0 | 23,665 | 0.4% | 01 Mar, 2024 |
| 14 | Kevin Bitterman | Director | 0 | 13,427 | 13,427 | 0.2% | 09 Sep, 2026 |
| 15 | Brian Richard Macdonald | Chief Innovation Officer | 12,276 | 0 | 12,276 | 0.2% | 30 Jun, 2023 |
| 16 | Brian Piekos | Cfo | 1,762 | 0 | 1,762 | 0.0% | 02 Jun, 2022 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 04 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 912 | $79.96 | $72.92K | 318,866 | Indirect |
| 04 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 759 | $79.96 | $60.69K | 312,230 | Indirect |
| 04 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 18 | $79.96 | $1.44K | 13,427 | Indirect |
| 01 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 70 | $79.95 | $5.60K | 349,140 | Indirect |
| 01 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 58 | $79.95 | $4.64K | 337,427 | Indirect |
| 01 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 1 | $79.95 | $80 | 14,012 | Indirect |
| 02 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 26,542 | $80.17 | $2.13Mn | 322,598 | Indirect |
| 02 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 22,090 | $80.17 | $1.77Mn | 315,337 | Indirect |
| 02 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 511 | $80.17 | $40.97K | 13,501 | Indirect |
| 02 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 10 | $80.98 | $810 | 322,588 | Indirect |
| 02 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 9 | $80.98 | $729 | 315,328 | Indirect |
| 02 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 2 | $80.98 | $162 | 13,499 | Indirect |
| 03 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 2,810 | $79.98 | $224.74K | 319,778 | Indirect |
| 03 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 2,339 | $79.98 | $187.07K | 312,989 | Indirect |
| 03 Sep, 2026 | Kevin Bitterman | Director | Disposed S | 54 | $79.98 | $4.32K | 13,445 | Indirect |
| 24 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Acquired M | 300 | $13.50 | $4.05K | 54,624 | Direct |
| 24 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Disposed S | 300 | $82.53 | $24.76K | 54,324 | Direct |
| 25 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Acquired M | 8,796 | $13.50 | $118.75K | 63,120 | Direct |
| 25 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Disposed S | 8,796 | $83.12 | $731.09K | 54,324 | Direct |
| 24 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Disposed M | 300 | $0.00 | $0 | 22,643 | Direct |