As of August 29, 2026, the three largest insider holders of IRON are Dmi Llc Ai (TenPercentOwner, 2.81Mn shares), Dmi Llc Ai (TenPercentOwner, 2.81Mn shares), Venture Fund X, L.P. Atlas (TenPercentOwner, 1.60Mn shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Dmi Llc Ai | TenPercentOwner | 2,814,379 | 0 | 2,814,379 | 44.5% | 24 Oct, 2025 |
| 2 | Venture Fund X, L.P. Atlas | TenPercentOwner | 1,402,186 | 198,326 | 1,600,512 | 25.3% | 25 Jan, 2024 |
| 3 | Holdings A/S Novo | TenPercentOwner | 1,090,772 | 0 | 1,090,772 | 17.2% | 28 Jun, 2023 |
| 4 | John D Quisel | Chief Executive Officer | 226,064 | 0 | 226,064 | 3.6% | 18 Aug, 2026 |
| 5 | Mona Ashiya | Director | 0 | 186,541 | 186,541 | 2.9% | 26 Mar, 2025 |
| 6 | Pamela Stephenson | Chief Commercial Officer | 80,998 | 0 | 80,998 | 1.3% | 17 Feb, 2026 |
| 7 | William Jacob Savage | Chief Medical Officer | 79,480 | 0 | 79,480 | 1.3% | 15 Apr, 2026 |
| 8 | Jean M. Franchi | Chief Financial Officer | 64,333 | 0 | 64,333 | 1.0% | 15 Apr, 2026 |
| 9 | Jonathan Yen-Wen Yu | Chief Operating Officer | 54,324 | 0 | 54,324 | 0.9% | 26 Aug, 2026 |
| 10 | Rahul Khara | Chief Legal Officer | 52,324 | 0 | 52,324 | 0.8% | 07 Aug, 2026 |
| 11 | Braden Michael Leonard | TenPercentOwner | 24,750 | 0 | 24,750 | 0.4% | 27 Oct, 2022 |
| 12 | Joanne Bryce | Chief Financial Officer | 23,665 | 0 | 23,665 | 0.4% | 01 Mar, 2024 |
| 13 | Kevin Bitterman | Director | 0 | 14,013 | 14,013 | 0.2% | 18 Dec, 2025 |
| 14 | Brian Richard Macdonald | Chief Innovation Officer | 12,276 | 0 | 12,276 | 0.2% | 30 Jun, 2023 |
| 15 | Brian Piekos | Cfo | 1,762 | 0 | 1,762 | 0.0% | 02 Jun, 2022 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 24 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Acquired M | 300 | $13.50 | $4.05K | 54,624 | Direct |
| 24 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Disposed S | 300 | $82.53 | $24.76K | 54,324 | Direct |
| 25 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Acquired M | 8,796 | $13.50 | $118.75K | 63,120 | Direct |
| 25 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Disposed S | 8,796 | $83.12 | $731.09K | 54,324 | Direct |
| 24 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Disposed M | 300 | $0.00 | $0 | 22,643 | Direct |
| 25 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Disposed M | 8,796 | $0.00 | $0 | 13,847 | Direct |
| 17 Aug, 2026 | John D Quisel | Chief Executive Officer | Acquired M | 33,000 | $13.50 | $445.50K | 259,064 | Direct |
| 17 Aug, 2026 | John D Quisel | Chief Executive Officer | Disposed S | 8,400 | $78.11 | $656.09K | 250,664 | Direct |
| 17 Aug, 2026 | John D Quisel | Chief Executive Officer | Disposed S | 12,712 | $79.20 | $1.01Mn | 237,952 | Direct |
| 17 Aug, 2026 | John D Quisel | Chief Executive Officer | Disposed S | 11,888 | $79.84 | $949.16K | 226,064 | Direct |
| 17 Aug, 2026 | John D Quisel | Chief Executive Officer | Disposed M | 33,000 | $0.00 | $0 | 91,586 | Direct |
| 12 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Acquired M | 804 | $13.50 | $10.85K | 55,128 | Direct |
| 12 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Disposed S | 804 | $82.64 | $66.44K | 54,324 | Direct |
| 12 Aug, 2026 | Jonathan Yen-Wen Yu | Chief Operating Officer | Disposed M | 804 | $0.00 | $0 | 22,943 | Direct |
| 06 Aug, 2026 | Rahul Khara | Chief Legal Officer | Acquired M | 5,000 | $14.69 | $73.45K | 57,324 | Direct |
| 06 Aug, 2026 | Rahul Khara | Chief Legal Officer | Disposed S | 5,000 | $80.00 | $400.00K | 52,324 | Direct |
| 06 Aug, 2026 | Rahul Khara | Chief Legal Officer | Disposed M | 5,000 | $0.00 | $0 | 49,804 | Direct |
| 13 Jul, 2026 | John D Quisel | Chief Executive Officer | Acquired M | 25,584 | $9.86 | $252.26K | 251,648 | Direct |
| 13 Jul, 2026 | John D Quisel | Chief Executive Officer | Acquired M | 7,416 | $13.50 | $100.12K | 259,064 | Direct |
| 13 Jul, 2026 | John D Quisel | Chief Executive Officer | Disposed S | 9,704 | $74.27 | $720.74K | 249,360 | Direct |