Inovio Pharmaceuticals, Inc. (INO) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

22,071,139Shares Outstanding

19,559Shares held by institutions

$31,881Value of institutional holdings

27.10%Institutional ownership %

-35.06%Shares Changed QoQ

135No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Inovio Pharmaceuticals, Inc. (NASDAQ:INO) includes 98 filers as of the latest reporting cycle ending December 2025.

The percentage of Inovio Pharmaceuticals owned by institutions changed from 39.3% in September 2025 to 63.4% in December 2025, marking a slight up trend.
On a quarter-over-quarter basis, institutional holdings shifted by 64.90%, with a year-over-year a decrease of 5.77% in the count of filers.
The latest 13F cycle for Inovio Pharmaceuticals reveals that of 98 total investors, 45 funds grew their exposure, whereas 21 reduced theirs and 32 made no changes.
This class of investors increased its holdings in Inovio Pharmaceuticals to 33.13Mn shares for the 13F-cycle ending December 2025, up by 13.04Mn shares quarter on quarter, and up 19.87Mn shares year over year.
FMR LLC's holding of 9.85Mn shares as of December 31, 2025 makes it the primary institutional investor in Inovio Pharmaceuticals, owning 18.83% of the stock.
Among the most significant buyers of Inovio Pharmaceuticals during December 2025 were FMR LLC (9.85Mn), ADAR1 Capital Management, LLC (1.56Mn), D. E. Shaw & Co., Inc. (1.43Mn), DIADEMA PARTNERS LP (633.68K), VANGUARD GROUP INC (602.71K).
Leading sellers of Inovio Pharmaceuticals stock in December 2025 included ADAGE CAPITAL PARTNERS GP, L.L.C. (875.00K), MORGAN STANLEY (680.95K), BANK OF AMERICA CORP /DE/ (570.27K), MILLENNIUM MANAGEMENT LLC (569.14K), RENAISSANCE TECHNOLOGIES LLC (263.18K).
The top 10 institutional holders of Inovio Pharmaceuticals for the quarter ending December 2025 included FMR LLC (9.85Mn), VANGUARD GROUP INC (3.32Mn), JANUS HENDERSON GROUP PLC (3.31Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (2.55Mn), Boxer Capital Management, LLC (2.42Mn), D. E. Shaw & Co., Inc. (2.23Mn), ADAR1 Capital Management, LLC (1.56Mn), MILLENNIUM MANAGEMENT LLC (1.40Mn), GEODE CAPITAL MANAGEMENT, LLC (769.36K), DIADEMA PARTNERS LP (633.68K).

98 Institutional Holders

19,559 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
FMR LLC	31 Dec, 2025	9,846,664	9,845,363	756,753.50%	$17,133,195.00
VANGUARD GROUP INC	31 Dec, 2025	3,315,580	602,708	22.22%	$5,769,110.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	3,308,406	42,146	1.29%	$5,773,168.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	2,553,571	-875,000	-25.52%	$4,443,214.00
Boxer Capital Management, LLC	31 Dec, 2025	2,420,122	120,122	5.22%	$4,211,012.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	2,231,811	1,425,069	176.64%	$3,883,351.00
ADAR1 Capital Management, LLC	31 Dec, 2025	1,560,508	1,560,508	0.00%	$2,715,284.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	1,403,379	-569,139	-28.85%	$2,441,879.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	769,356	222,609	40.72%	$1,339,699.00
DIADEMA PARTNERS LP	31 Dec, 2025	633,682	633,682	0.00%	$1,102,607.00
BlackRock, Inc.	31 Dec, 2025	617,869	118,466	23.72%	$1,075,092.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	553,164	-263,175	-32.24%	$962,505.00
GSA CAPITAL PARTNERS LLP	31 Dec, 2025	459,828	16,724	3.77%	$800.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	322,739	31,939	10.98%	$561,566.00
NORTHERN TRUST CORP	31 Dec, 2025	299,984	61,513	25.79%	$521,973.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	250,950	199,768	390.31%	$436,653.00
683 Capital Management, LLC	31 Dec, 2025	248,790	248,790	0.00%	$432,895.00
STATE STREET CORP	31 Dec, 2025	247,410	61,200	32.87%	$430,493.00
OMERS ADMINISTRATION Corp	31 Dec, 2025	223,000	223,000	0.00%	$388,020.00
BRIDGEWAY CAPITAL MANAGEMENT, LLC	31 Dec, 2025	173,000	173,000	0.00%	$301,020.00

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