Across the past 12 months, open-market trades by Iambic Therapeutics insiders were all purchases, totaling $11.5 million (718.75K shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Frederick R Manby | Chief Technology Officer | 1,862,665 | 0 | 1,862,665 | 34.5% | 16 Oct, 2026 |
| 2 | Thomas F. Miller | Chief Executive Officer | 1,410,756 | 0 | 1,410,756 | 26.1% | 16 Oct, 2026 |
| 3 | Capital Management, Lp Catalio | TenPercentOwner | 0 | 742,546 | 742,546 | 13.8% | 19 Oct, 2026 |
| 4 | R Jacob Vogelstein | Director | 0 | 742,546 | 742,546 | 13.8% | 19 Oct, 2026 |
| 5 | Michael Secora | Cfo Chief Corp Dev Ofcr | 279,902 | 0 | 279,902 | 5.2% | 19 Oct, 2026 |
| 6 | William H Rastetter | Director, Other | 0 | 200,920 | 200,920 | 3.7% | 19 Oct, 2026 |
| 7 | Neil Josephson | Chief Medical Officer | 71,459 | 0 | 71,459 | 1.3% | 16 Oct, 2026 |
| 8 | Evan Lockwood Rachlin | Director | 0 | 57,754 | 57,754 | 1.1% | 19 Oct, 2026 |
| 9 | Peter A Olson | Chief Scientific Officer | 30,909 | 0 | 30,909 | 0.6% | 16 Oct, 2026 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 16 Oct, 2026 | Capital Management, Lp Catalio | TenPercentOwner | Acquired C | 1,995,749 | — | — | 1,995,749 | Indirect |
| 16 Oct, 2026 | Evan Lockwood Rachlin | Director | Acquired C | 1,458,736 | — | — | 1,458,736 | Indirect |
| 16 Oct, 2026 | R Jacob Vogelstein | Director | Acquired C | 1,995,749 | — | — | 1,995,749 | Indirect |
| 16 Oct, 2026 | William H Rastetter | Director, Other | Acquired C | 192,579 | — | — | 192,579 | Indirect |
| 16 Oct, 2026 | Michael Secora | Cfo Chief Corp Dev Ofcr | Acquired C | 61,342 | — | — | 279,902 | Direct |
| 16 Oct, 2026 | R Jacob Vogelstein | Director | Acquired C | 1,458,290 | — | — | 1,458,290 | Indirect |
| 16 Oct, 2026 | William H Rastetter | Director, Other | Acquired C | 8,341 | — | — | 200,920 | Indirect |
| 16 Oct, 2026 | Capital Management, Lp Catalio | TenPercentOwner | Acquired C | 1,458,290 | — | — | 1,458,290 | Indirect |
| 16 Oct, 2026 | Evan Lockwood Rachlin | Director | Acquired C | 410,762 | — | — | 1,869,498 | Indirect |
| 16 Oct, 2026 | Michael Secora | Cfo Chief Corp Dev Ofcr | Disposed C | 61,342 | $0.00 | $0 | 0 | Direct |
| 16 Oct, 2026 | Capital Management, Lp Catalio | TenPercentOwner | Acquired C | 742,546 | — | — | 742,546 | Indirect |
| 16 Oct, 2026 | Evan Lockwood Rachlin | Director | Acquired P | 718,750 | $16.00 | $11.50Mn | 2,588,248 | Indirect |
| 16 Oct, 2026 | William H Rastetter | Director, Other | Disposed C | 76,801 | $0.00 | $0 | 0 | Indirect |
| 16 Oct, 2026 | R Jacob Vogelstein | Director | Acquired C | 742,546 | — | — | 742,546 | Indirect |
| 16 Oct, 2026 | R Jacob Vogelstein | Director | Disposed C | 1,141,878 | $0.00 | $0 | 0 | Indirect |
| 16 Oct, 2026 | Capital Management, Lp Catalio | TenPercentOwner | Disposed C | 1,141,878 | $0.00 | $0 | 0 | Indirect |
| 16 Oct, 2026 | William H Rastetter | Director, Other | Disposed C | 64,001 | $0.00 | $0 | 0 | Indirect |
| 16 Oct, 2026 | Evan Lockwood Rachlin | Director | Acquired C | 57,754 | — | — | 57,754 | Indirect |
| 16 Oct, 2026 | William H Rastetter | Director, Other | Disposed C | 36,805 | $0.00 | $0 | 0 | Indirect |
| 16 Oct, 2026 | Capital Management, Lp Catalio | TenPercentOwner | Disposed C | 731,187 | $0.00 | $0 | 0 | Indirect |