Heron Therapeutics, Inc. /De/ (HRTX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

170,348,000Shares Outstanding

157,475,641Shares held by institutions

$160,625,154Value of institutional holdings

92.44%Institutional ownership %

6.68%Shares Changed QoQ

168No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Heron Therapeutics, Inc. /De/ (NASDAQ:HRTX) appears in 168 institutional 13F filings for the quarter ending December 2025.

These investors collectively held 91.8% of Heron Therapeutics's outstanding shares in December 2025, up from 90.8% in September 2025.
They increased total shares held in Heron Therapeutics by 6.35% from the prior quarter, while the number of investors in HRTX increased 6.33% year over year.
Of these 168 holders, 81 added to their stakes in Heron Therapeutics, 44 trimmed positions, and 43 made no changes.
The aggregate institutional position in Heron Therapeutics amounted to 156.45Mn shares as of December 2025, up by 9.34Mn shares quarter on quarter, and up 36.82Mn shares year over year.
As of December 31, 2025, the biggest holder of Heron Therapeutics is Rubric Capital Management LP at 30.05Mn shares, representing 17.64% of shares outstanding.
The biggest buyers of Heron Therapeutics for the quarter ending December 2025 included MILLENNIUM MANAGEMENT LLC (6.92Mn), TANG CAPITAL MANAGEMENT LLC (2.8Mn), Clearline Capital LP (2.52Mn), VANGUARD GROUP INC (1.36Mn), JANE STREET GROUP, LLC (1.15Mn).
Leading sellers of Heron Therapeutics shares for the quarter ending December 2025 were Jpmorgan Chase & Co (2.52Mn), Citigroup Inc (2.47Mn), AQR CAPITAL MANAGEMENT LLC (1.56Mn), Morgan Stanley (1.5Mn), Bank Of America Corp /De/ (1.33Mn).
According to Business Quant data, leading holders of HRTX for December 2025 are Rubric Capital Management LP (30.05Mn), Clearline Capital LP (12.24Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (11.19Mn), BlackRock, Inc. (10.22Mn), VANGUARD GROUP INC (9.82Mn), Velan Capital Investment Management LP (8.75Mn), MILLENNIUM MANAGEMENT LLC (7.17Mn), PALISADE CAPITAL MANAGEMENT, LP (6.33Mn), TANG CAPITAL MANAGEMENT LLC (6.25Mn), Tejara Capital Ltd (5.13Mn).

168 Institutional Holders

157,475,641 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Rubric Capital Management LP	31 Dec, 2025	30,046,828	946,100	3.25%	$39,060,876.00
Clearline Capital LP	31 Dec, 2025	12,235,239	2,522,712	25.97%	$15,905,811.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	11,185,325	946,100	9.24%	$14,540,923.00
BlackRock, Inc.	31 Dec, 2025	10,218,236	230,776	2.31%	$13,283,708.00
VANGUARD GROUP INC	31 Dec, 2025	9,820,384	1,360,600	16.08%	$12,766,499.00
Velan Capital Investment Management LP	31 Dec, 2025	8,753,290	0	0.00%	$11,379,277.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	7,169,908	6,921,405	2,785.24%	$9,320,880.00
PALISADE CAPITAL MANAGEMENT, LP	31 Dec, 2025	6,326,113	-1,001,334	-13.67%	$8,223,947.00
TANG CAPITAL MANAGEMENT LLC	31 Dec, 2025	6,250,000	2,800,000	81.16%	$8,125,000.00
Tejara Capital Ltd	31 Dec, 2025	5,131,426	541,711	11.80%	$6,670,854.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	4,081,222	438,240	12.03%	$5,306,435.00
State Street Corp	31 Dec, 2025	3,778,043	126,540	3.47%	$4,911,456.00
JW Asset Management, LLC	31 Dec, 2025	3,671,073	378,440	11.49%	$4,772,395.00
Congress Park Capital LLC	31 Dec, 2025	3,067,475	177,318	6.14%	$3,987,718.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	3,004,640	-83,852	-2.71%	$3,906,032.00
NEW YORK STATE COMMON RETIREMENT FUND	31 Dec, 2025	2,576,716	0	0.00%	$3,349,731.00
CITADEL ADVISORS LLC	31 Dec, 2025	2,095,045	-613,412	-22.65%	$2,723,559.00
UBS Group AG	31 Dec, 2025	2,091,669	-842,412	-28.71%	$2,719,170.00
Goldman Sachs Group Inc	31 Dec, 2025	1,979,483	654,681	49.42%	$2,573,329.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	1,915,900	-939,099	-32.89%	$2,490,670.00

1 - 20 of 168

Research Tools