As of September 29, 2026, the three largest insider holders of HRTX are Capital Management Lp Rubric (TenPercentOwner, 30.05Mn shares), Adam Morgan (Director, 8.75Mn shares), Adam Morgan (Director, 6.99Mn shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Capital Management Lp Rubric | TenPercentOwner | 0 | 30,046,828 | 30,046,828 | 76.1% | 17 Oct, 2025 |
| 2 | Adam Morgan | Director | 123,737 | 6,986,744 | 7,110,481 | 18.0% | 03 Feb, 2026 |
| 3 | Craig A Collard | Chief Executive Officer | 856,492 | 0 | 856,492 | 2.2% | 03 Aug, 2026 |
| 4 | Ira Duarte | Evp, Chief Financial Officer | 281,899 | 0 | 281,899 | 0.7% | 03 Aug, 2026 |
| 5 | William P Forbes | Evp, Chief Development Officer | 241,173 | 0 | 241,173 | 0.6% | 03 Aug, 2026 |
| 6 | Barry D Quart | Chief Executive Officer | 177,989 | 0 | 177,989 | 0.5% | 17 Jan, 2023 |
| 7 | Mark Earl Hensley | Chief Operating Officer | 170,901 | 0 | 170,901 | 0.4% | 10 Aug, 2026 |
| 8 | Susan Rodriguez | Director | 87,180 | 0 | 87,180 | 0.2% | 04 Feb, 2025 |
| 9 | Lisa Peraza | Vp, Chief Accounting Officer | 55,907 | 0 | 55,907 | 0.1% | 16 Jan, 2024 |
| 10 | Waage Christian | Director | 53,960 | 0 | 53,960 | 0.1% | 03 Feb, 2026 |
| 11 | Craig A Johnson | Director | 53,960 | 0 | 53,960 | 0.1% | 03 Feb, 2026 |
| 12 | Michael Kaseta | Director | 53,960 | 0 | 53,960 | 0.1% | 03 Feb, 2026 |
| 13 | Thomas Cusack | Director | 53,960 | 0 | 53,960 | 0.1% | 03 Feb, 2026 |
| 14 | Sharmila Dissanaike | Director | 53,960 | 0 | 53,960 | 0.1% | 03 Feb, 2026 |
| 15 | Stephen Davis | Director | 52,032 | 0 | 52,032 | 0.1% | 20 Dec, 2022 |
| 16 | John Poyhonen | President Cco | 46,648 | 0 | 46,648 | 0.1% | 17 Apr, 2023 |
| 17 | David Leslie Szekeres | Evp, Chief Operating Officer | 33,754 | 0 | 33,754 | 0.1% | 17 Jul, 2023 |
| 18 | Kimberly Manhard | Evp, Drug Development | 28,330 | 0 | 28,330 | 0.1% | 17 Apr, 2023 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 06 Aug, 2026 | Mark Earl Hensley | Chief Operating Officer | Acquired M | 31,250 | — | — | 179,789 | Direct |
| 06 Aug, 2026 | Mark Earl Hensley | Chief Operating Officer | Disposed F | 8,888 | $0.50 | $4.44K | 170,901 | Direct |
| 06 Aug, 2026 | Mark Earl Hensley | Chief Operating Officer | Disposed M | 31,250 | $0.00 | $0 | 343,750 | Direct |
| 30 Jul, 2026 | Craig A Collard | Chief Executive Officer | Acquired M | 50,021 | — | — | 821,703 | Direct |
| 30 Jul, 2026 | William P Forbes | Evp, Chief Development Officer | Acquired M | 11,769 | — | — | 236,153 | Direct |
| 30 Jul, 2026 | Ira Duarte | Evp, Chief Financial Officer | Acquired M | 13,535 | — | — | 277,381 | Direct |
| 31 Jul, 2026 | Mark Earl Hensley | Chief Operating Officer | Acquired M | 11,769 | — | — | 148,539 | Direct |
| 30 Jul, 2026 | William P Forbes | Evp, Chief Development Officer | Disposed F | 3,348 | $0.50 | $1.67K | 232,805 | Direct |
| 31 Jul, 2026 | Mark Earl Hensley | Chief Operating Officer | Disposed M | 11,769 | $0.00 | $0 | 164,776 | Direct |
| 31 Jul, 2026 | Craig A Collard | Chief Executive Officer | Acquired M | 34,789 | — | — | 856,492 | Direct |
| 30 Jul, 2026 | Ira Duarte | Evp, Chief Financial Officer | Disposed F | 3,850 | $0.50 | $1.93K | 273,531 | Direct |
| 31 Jul, 2026 | William P Forbes | Evp, Chief Development Officer | Acquired M | 11,694 | — | — | 244,499 | Direct |
| 30 Jul, 2026 | Craig A Collard | Chief Executive Officer | Disposed M | 50,021 | $0.00 | $0 | 700,295 | Direct |
| 31 Jul, 2026 | Ira Duarte | Evp, Chief Financial Officer | Acquired M | 11,694 | — | — | 285,225 | Direct |
| 31 Jul, 2026 | Craig A Collard | Chief Executive Officer | Disposed M | 34,789 | $0.00 | $0 | 347,886 | Direct |
| 31 Jul, 2026 | William P Forbes | Evp, Chief Development Officer | Disposed F | 3,326 | $0.50 | $1.66K | 241,173 | Direct |
| 31 Jul, 2026 | Ira Duarte | Evp, Chief Financial Officer | Disposed F | 3,326 | $0.50 | $1.66K | 281,899 | Direct |
| 30 Jul, 2026 | William P Forbes | Evp, Chief Development Officer | Disposed M | 11,769 | $0.00 | $0 | 164,776 | Direct |
| 30 Jul, 2026 | Ira Duarte | Evp, Chief Financial Officer | Disposed M | 13,535 | $0.00 | $0 | 189,492 | Direct |
| 31 Jul, 2026 | Ira Duarte | Evp, Chief Financial Officer | Disposed M | 11,694 | $0.00 | $0 | 116,944 | Direct |